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Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021.
GBD 2021 Diseases and Injuries Collaborators. GBD 2021 Diseases and Injuries Collaborators. Lancet. 2024 Apr 15:S0140-6736(24)00757-8. doi: 10.1016/S0140-6736(24)00757-8. Online ahead of print. Lancet. 2024. PMID: 38642570 Free article.
Age-standardised DALY rates due to injuries decreased globally by 24.0% (20.7-27.2) between 2010 and 2021, although improvements were not uniform across locations, ages, and sexes. Globally, HALE at birth improved slightly, from 61.3 years (58.6-63.6) in 2010 to 62.2 years …
Age-standardised DALY rates due to injuries decreased globally by 24.0% (20.7-27.2) between 2010 and 2021, although improvements were not un …
Global age-sex-specific mortality, life expectancy, and population estimates in 204 countries and territories and 811 subnational locations, 1950-2021, and the impact of the COVID-19 pandemic: a comprehensive demographic analysis for the Global Burden of Disease Study 2021.
GBD 2021 Demographics Collaborators. GBD 2021 Demographics Collaborators. Lancet. 2024 Mar 8:S0140-6736(24)00476-8. doi: 10.1016/S0140-6736(24)00476-8. Online ahead of print. Lancet. 2024. PMID: 38484753 Free article.
Global life expectancy at birth declined by 1.6 years (1.0-2.2) between 2019 and 2021, reversing historical trends. ...The comprehensive demographic estimates reported here will enable researchers, policy makers, health practitioners, and other key stakeholders to better u …
Global life expectancy at birth declined by 1.6 years (1.0-2.2) between 2019 and 2021, reversing historical trends. ...The comprehens …
Real-World Effectiveness of PCSK9 Inhibitors in Reducing LDL-C in Patients With Familial Hypercholesterolemia in Italy: A Retrospective Cohort Study Based on the AIFA Monitoring Registries.
Arca M, Celant S, Olimpieri PP, Colatrella A, Tomassini L, D'Erasmo L, Averna M, Zambon A, Catapano AL, Russo P. Arca M, et al. Among authors: catapano al. J Am Heart Assoc. 2023 Nov 7;12(21):e026550. doi: 10.1161/JAHA.122.026550. Epub 2023 Oct 18. J Am Heart Assoc. 2023. PMID: 37850449 Free PMC article.
Background Information on the real-world use of proprotein convertase subtilisin kexin 9 inhibitors (PCKS9is) in familial hypercholesterolemia are limited. We evaluated the pattern of prescription and the long-term efficacy of alirocumab and evolocumab in Italian patients …
Background Information on the real-world use of proprotein convertase subtilisin kexin 9 inhibitors (PCKS9is) in familial hypercholesterolem …
Metabolic syndrome is associated with similar long-term prognosis in those living with and without obesity: an analysis of 45 615 patients from the nationwide LIPIDOGRAM 2004-2015 studies.
Osadnik K, Osadnik T, Gierlotka M, Windak A, Tomasik T, Mastej M, Kuras A, Jóźwiak K, Penson PE, Lip GYH, Mikhailidis DP, Toth PP, Catapano AL, Ray KK, Howard G, Tomaszewski M, Charchar FJ, Sattar N, Williams B, MacDonald TM, Banach M, Jóźwiak J. Osadnik K, et al. Among authors: catapano al. Eur J Prev Cardiol. 2023 Sep 6;30(12):1195-1204. doi: 10.1093/eurjpc/zwad101. Eur J Prev Cardiol. 2023. PMID: 37039119
AIMS: We aimed to evaluate the association between metabolic syndrome (MetS) and long-term all-cause mortality. METHODS AND RESULTS: The LIPIDOGRAM studies were carried out in the primary care in Poland in 2004, 2006, and 2015. ...An additional finding, which is important …
AIMS: We aimed to evaluate the association between metabolic syndrome (MetS) and long-term all-cause mortality. METHODS AND RESULTS: …
Red yeast rice for dyslipidaemias and cardiovascular risk reduction: A position paper of the International Lipid Expert Panel.
Banach M, Catapano AL, Cicero AFG, Escobar C, Foger B, Katsiki N, Latkovskis G, Rakowski M, Reiner Z, Sahebkar A, Sikand G, Penson PE, On Behalf Of The International Lipid Expert Panel Ilep. Banach M, et al. Among authors: catapano al. Pharmacol Res. 2022 Sep;183:106370. doi: 10.1016/j.phrs.2022.106370. Epub 2022 Jul 25. Pharmacol Res. 2022. PMID: 35901940 Free article. Review.
Lipid-lowering therapy (using statins, ezetimibe and PCSK9 inhibitors) substantially ameliorates the risk and is associated with long-term reduction in cardiovascular (CV) events. The robust evidence supporting these therapies supports their continued (and expanding) role …
Lipid-lowering therapy (using statins, ezetimibe and PCSK9 inhibitors) substantially ameliorates the risk and is associated with long-ter …
Long-Term Safety and Efficacy of Bempedoic Acid in Patients With Atherosclerotic Cardiovascular Disease and/or Heterozygous Familial Hypercholesterolemia (from the CLEAR Harmony Open-Label Extension Study).
Ballantyne CM, Banach M, Bays HE, Catapano AL, Laufs U, Stroes ESG, Robinson P, Lei L, Ray KK. Ballantyne CM, et al. Among authors: catapano al. Am J Cardiol. 2022 Jul 1;174:1-11. doi: 10.1016/j.amjcard.2022.03.020. Epub 2022 Apr 26. Am J Cardiol. 2022. PMID: 35483979 Free article. Clinical Trial.
Limited data exist on the long-term safety and efficacy of bempedoic acid, an adenosine triphosphate-citrate lyase inhibitor, for lowering low-density lipoprotein cholesterol (LDL-C). ...
Limited data exist on the long-term safety and efficacy of bempedoic acid, an adenosine triphosphate-citrate lyase inhibitor, for low …
HDL in Atherosclerotic Cardiovascular Disease: In Search of a Role.
Casula M, Colpani O, Xie S, Catapano AL, Baragetti A. Casula M, et al. Among authors: catapano al. Cells. 2021 Jul 23;10(8):1869. doi: 10.3390/cells10081869. Cells. 2021. PMID: 34440638 Free PMC article. Review.
These findings have prompted a reconsideration of the biological functions of HDL that can be summarized with the word "HDL functionality", a term that embraces the many reported biological activities beyond the so-called reverse cholesterol transport, to explain this lack …
These findings have prompted a reconsideration of the biological functions of HDL that can be summarized with the word "HDL functionality", …
Reduction of Cardio-Metabolic Risk and Body Weight through a Multiphasic Very-Low Calorie Ketogenic Diet Program in Women with Overweight/Obesity: A Study in a Real-World Setting.
Tragni E, Vigna L, Ruscica M, Macchi C, Casula M, Santelia A, Catapano AL, Magni P. Tragni E, et al. Among authors: catapano al. Nutrients. 2021 May 26;13(6):1804. doi: 10.3390/nu13061804. Nutrients. 2021. PMID: 34073344 Free PMC article.
Among lifestyle approaches, very low-calorie ketogenic diets (VLCKD) have been shown to lead to rapid initial weight loss, resulting in better long-term weight loss maintenance. As no information on VLCKD studies carried on in a real-world setting are available, we conduct …
Among lifestyle approaches, very low-calorie ketogenic diets (VLCKD) have been shown to lead to rapid initial weight loss, resulting in bett …
Genetically determined hypercholesterolaemia results into premature leucocyte telomere length shortening and reduced haematopoietic precursors.
Baragetti A, Bonacina F, Da Dalt L, Moregola A, Zampoleri V, Pellegatta F, Grigore L, Pirillo A, Spina R, Cefalù AB, Averna M, Norata GD, Catapano AL. Baragetti A, et al. Among authors: catapano al. Eur J Prev Cardiol. 2022 May 5;29(5):721-729. doi: 10.1093/eurjpc/zwaa115. Eur J Prev Cardiol. 2022. PMID: 33624064
Shorter LTL was confirmed in leucocytes of LDLR-KO vs. wild-type mice and associated with lower abundance of long-term haematopoietic stem and progenitor cells (LT-HSPCs) in the bone marrow. ...
Shorter LTL was confirmed in leucocytes of LDLR-KO vs. wild-type mice and associated with lower abundance of long-term haematopoietic …
The Expected 30-Year Benefits of Early Versus Delayed Primary Prevention of Cardiovascular Disease by Lipid Lowering.
Pencina MJ, Pencina KM, Lloyd-Jones D, Catapano AL, Thanassoulis G, Sniderman AD. Pencina MJ, et al. Among authors: catapano al. Circulation. 2020 Sep;142(9):827-837. doi: 10.1161/CIRCULATIONAHA.120.045851. Epub 2020 Jul 23. Circulation. 2020. PMID: 32700572
We estimated the absolute and relative impact of lipid lowering as a function of age, age at initiation, and non-high-density lipoprotein cholesterol (HDL-C) level on the expected rates of atherosclerotic cardiovascular disease over the succeeding 30 years. We modeled expected ri …
We estimated the absolute and relative impact of lipid lowering as a function of age, age at initiation, and non-high-density lipoprotein ch …
32 results