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"Bad Luck Mutations": DNA Mutations Are not the Whole Answer to Understanding Cancer Risk.
Trosko JE, Carruba G. Trosko JE, et al. Among authors: carruba g. Dose Response. 2017 Jun 30;15(2):1559325817716585. doi: 10.1177/1559325817716585. eCollection 2017 Apr-Jun. Dose Response. 2017. PMID: 28717349 Free PMC article.
While support for both interpretations provides some validity, both interpretations ignore several concepts of the multistage, multimechanism process of carcinogenesis, namely, (1) mutations can be generated by both "errors of DNA repair" and "errors of DNA replication," during t …
While support for both interpretations provides some validity, both interpretations ignore several concepts of the multistage, multimechanis …
Italian cancer figures, report 2012: Cancer in children and adolescents.
AIRTUM Working Group; CCM; AIEOP Working Group. AIRTUM Working Group, et al. Epidemiol Prev. 2013 Jan-Feb;37(1 Suppl 1):1-225. Epidemiol Prev. 2013. PMID: 23585445 Free article. English, Italian.
Health organizational aspects of treatment services for paediatric patients, based on the AIEOP database, are also discussed, along with long-term complications in cured patients. The third section describes the changes in mortality trends due to improving therapies and he …
Health organizational aspects of treatment services for paediatric patients, based on the AIEOP database, are also discussed, along with lon …
Italian cancer figures, report 2010: Cancer prevalence in Italy. Patients living with cancer, long-term survivors and cured patients.
AIRTUM Working Group. AIRTUM Working Group. Epidemiol Prev. 2010 Sep-Dec;34(5-6 Suppl 2):1-188. Epidemiol Prev. 2010. PMID: 21220827 Free article. English, Italian.
OBJECTIVES: the aim of the present monograph is to update the estimation of the number of people living with cancer in Italy, to describe geographic variability, and estimate the number of long-term survivors, i.e., people living five years or more after a cancer diagnosis …
OBJECTIVES: the aim of the present monograph is to update the estimation of the number of people living with cancer in Italy, to describe ge …
Estrogen and prostate cancer: an eclipsed truth in an androgen-dominated scenario.
Carruba G. Carruba G. J Cell Biochem. 2007 Nov 1;102(4):899-911. doi: 10.1002/jcb.21529. J Cell Biochem. 2007. PMID: 17786930 Review.
Although the mechanisms underlying the hormonal induction of prostate cancer in experimental animals remain uncertain, there is however evidence to support the assumption that long term administration of androgens and estrogens results in an estrogenic milieu in rat prosta …
Although the mechanisms underlying the hormonal induction of prostate cancer in experimental animals remain uncertain, there is however evid …
Tissue content of hydroxyestrogens in relation to survival of breast cancer patients.
Castagnetta LA, Granata OM, Traina A, Ravazzolo B, Amoroso M, Miele M, Bellavia V, Agostara B, Carruba G. Castagnetta LA, et al. Among authors: carruba g. Clin Cancer Res. 2002 Oct;8(10):3146-55. Clin Cancer Res. 2002. PMID: 12374682
PURPOSE: The main goal of our study was to assess estrogen contents of breast tumor tissues, having different estrogen receptor status, in relation to long-term follow-up of patients. EXPERIMENTAL DESIGN: Twenty-one breast cancer cases, all collected from January 1986 to J …
PURPOSE: The main goal of our study was to assess estrogen contents of breast tumor tissues, having different estrogen receptor status, in r …
17 beta-Hydroxysteroid dehydrogenase activity in endometrial cancer cells: different metabolic pathways of estradiol in hormone-responsive and non-responsive intact cells.
Castagnetta LA, Montesanti AM, Granata OM, Oliveri G, Sorci CM, Amodio R, Liquori M, Carruba G. Castagnetta LA, et al. Among authors: carruba g. J Steroid Biochem Mol Biol. 1995 Dec;55(5-6):573-9. doi: 10.1016/0960-0760(95)00208-1. J Steroid Biochem Mol Biol. 1995. PMID: 8547184
In this paper we report that two human long-term endometrial cancer cell lines, Ishikawa and HEC-1A, exhibit quite different abilities in metabolizing estrogens. ...
In this paper we report that two human long-term endometrial cancer cell lines, Ishikawa and HEC-1A, exhibit quite different abilitie …
Steroid-growth factor interaction in human prostate cancer. 1. Short-term effects of transforming growth factors on growth of human prostate cancer cells.
Carruba G, Leake RE, Rinaldi F, Chalmers D, Comito L, Sorci C, Pavone-Macaluso M, Castagnetta LA. Carruba G, et al. Steroids. 1994 Jul;59(7):412-20. doi: 10.1016/0039-128x(94)90010-8. Steroids. 1994. PMID: 7974525
In order to better define potential mechanisms of growth regulation in human prostate cancer cells, we have compared biological responses (such as short-term response to both transforming growth factor alpha and beta; TFG alpha and TFG beta) in relation to hormone sensitiv …
In order to better define potential mechanisms of growth regulation in human prostate cancer cells, we have compared biological responses (s …
Prostate long-term epithelial cell lines. Biological and biochemical features.
Castagnetta L, Carruba G, Granata OM, Lo Casto M, Arcuri F, Mesiti M, Pavone-Macaluso M. Castagnetta L, et al. Among authors: carruba g. Ann N Y Acad Sci. 1990;595:149-64. doi: 10.1111/j.1749-6632.1990.tb34289.x. Ann N Y Acad Sci. 1990. PMID: 2375602
This review reports studies on long-term prostate cell lines using multiple experimental approaches. ...The divergent steroid metabolic pathway we observe in different prostate long-term cells appears to be an intrinsic, consistent, highly reproducible property of e …
This review reports studies on long-term prostate cell lines using multiple experimental approaches. ...The divergent steroid metabol …
Estrone conversion rates by human endometrial cancer cell lines.
Castagnetta L, Granata OM, Lo Casto M, Miserendino V, Calò M, Carruba G. Castagnetta L, et al. Among authors: carruba g. J Steroid Biochem. 1986 Nov;25(5B):803-9. doi: 10.1016/0022-4731(86)90312-2. J Steroid Biochem. 1986. PMID: 3807365
Studies on estrone metabolism by long term human endometrial cancer HEC-1A and Ishikawa cell lines are reported. ...
Studies on estrone metabolism by long term human endometrial cancer HEC-1A and Ishikawa cell lines are reported. ...
Modulation of oestrogen excretion profiles by adjuvant chemotherapy in pre- and postmenopausal breast cancer.
Castagnetta L, Traina A, Ciaccio M, Carruba G, Polito L, Di Carlo A. Castagnetta L, et al. Among authors: carruba g. J Steroid Biochem. 1985 Dec;23(6B):1115-22. doi: 10.1016/0022-4731(85)90029-9. J Steroid Biochem. 1985. PMID: 3005773
However, comparing 9 breast cancer patients, when having had both short-term and non-short-term CMF treatment, the effects on steroid excretion patterns appear to arise at an early stage....
However, comparing 9 breast cancer patients, when having had both short-term and non-short-term CMF treatment, the effects on …
11 results