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Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021.
GBD 2021 Diseases and Injuries Collaborators. GBD 2021 Diseases and Injuries Collaborators. Lancet. 2024 Apr 15:S0140-6736(24)00757-8. doi: 10.1016/S0140-6736(24)00757-8. Online ahead of print. Lancet. 2024. PMID: 38642570
Age-standardised DALY rates due to injuries decreased globally by 24.0% (20.7-27.2) between 2010 and 2021, although improvements were not uniform across locations, ages, and sexes. Globally, HALE at birth improved slightly, from 61.3 years (58.6-63.6) in 2010 to 62.2 years …
Age-standardised DALY rates due to injuries decreased globally by 24.0% (20.7-27.2) between 2010 and 2021, although improvements were not un …
Global age-sex-specific mortality, life expectancy, and population estimates in 204 countries and territories and 811 subnational locations, 1950-2021, and the impact of the COVID-19 pandemic: a comprehensive demographic analysis for the Global Burden of Disease Study 2021.
GBD 2021 Demographics Collaborators. GBD 2021 Demographics Collaborators. Lancet. 2024 Mar 8:S0140-6736(24)00476-8. doi: 10.1016/S0140-6736(24)00476-8. Online ahead of print. Lancet. 2024. PMID: 38484753 Free article.
Global life expectancy at birth declined by 1.6 years (1.0-2.2) between 2019 and 2021, reversing historical trends. ...The comprehensive demographic estimates reported here will enable researchers, policy makers, health practitioners, and other key stakeholders to better u …
Global life expectancy at birth declined by 1.6 years (1.0-2.2) between 2019 and 2021, reversing historical trends. ...The comprehens …
ECFS standards of care on CFTR-related disorders: Towards a comprehensive program for affected individuals.
De Wachter E, De Boeck K, Sermet-Gaudelus I, Simmonds NJ, Munck A, Naehrlich L, Barben J, Boyd C, Veen SJ, Carr SB, Fajac I, Farrell PM, Girodon E, Gonska T, Grody WW, Jain M, Jung A, Kerem E, Raraigh KS, van Koningsbruggen-Rietschel S, Waller MD, Southern KW, Castellani C; ECFS Diagnostic Network Working Group. De Wachter E, et al. Among authors: carr sb. J Cyst Fibros. 2024 Feb 21:S1569-1993(24)00011-0. doi: 10.1016/j.jcf.2024.01.012. Online ahead of print. J Cyst Fibros. 2024. PMID: 38388234
Topics included are: 1) benefits and obstacles to collect data from pwCFTR-RD are discussed, together with the opportunity to integrate them into established CF-registries; 2) the potential of infants designated CRMS/CFSPID to develop a CFTR-RD and how to communicate this informa …
Topics included are: 1) benefits and obstacles to collect data from pwCFTR-RD are discussed, together with the opportunity to integrate them …
Online Resources for Robin Sequence; an Analysis of Readability.
Browne R, Hurley CM, Carr S, de Blacam C. Browne R, et al. Among authors: carr s. Cleft Palate Craniofac J. 2024 Feb 19:10556656241234587. doi: 10.1177/10556656241234587. Online ahead of print. Cleft Palate Craniofac J. 2024. PMID: 38373442
The objective was to evaluate the readability of easily accessible parent-directed information concerning Robin Sequence (RS) online, compared to the American Medical Association (AMA)-recommended sixth grade (age 11-12) readability level. A Google search of the term "Pier …
The objective was to evaluate the readability of easily accessible parent-directed information concerning Robin Sequence (RS) online, compar …
Association between ethnicity and migration status with the prevalence of single and multiple long-term conditions in UK healthcare workers.
Ekezie W, Martin CA, Baggaley RF, Teece L, Nazareth J, Pan D, Sze S, Bryant L, Woolf K, Gray LJ, Khunti K, Pareek M; UK-REACH study collaborative group. Ekezie W, et al. BMC Med. 2023 Nov 30;21(1):433. doi: 10.1186/s12916-023-03109-w. BMC Med. 2023. PMID: 38031115 Free PMC article.
However, little is known about the prevalence and patterns of long-term medical conditions in HCWs, especially those from ethnic minorities. This study evaluated the burden of multiple long-term conditions (MLTCs), i.e. the presence of two or more single long-ter …
However, little is known about the prevalence and patterns of long-term medical conditions in HCWs, especially those from ethnic mino …
Peer teacher training develops "lifelong skills".
Karia CT, Anderson E, Burgess A, Carr S. Karia CT, et al. Among authors: carr s. Med Teach. 2024 Mar;46(3):373-379. doi: 10.1080/0142159X.2023.2256463. Epub 2023 Oct 2. Med Teach. 2024. PMID: 37783200
However, there is limited literature on preparing students for this role, known as Peer Teacher Training (PTT), and exploring its long-term impact. This study investigates the impact of a previously implemented PTT programme on participants' application to clinical practic …
However, there is limited literature on preparing students for this role, known as Peer Teacher Training (PTT), and exploring its long-te …
Impacts of health care service changes implemented due to COVID-19 on children and young people with long-term disability: A mapping review.
Merrick H, Driver H, Main C, Kenny RPW, Richmond C, Allard A, Bola K, Morris C, Parr JR, Pearson F, Pennington L; Resetting Services Team. Merrick H, et al. Dev Med Child Neurol. 2023 Jul;65(7):885-899. doi: 10.1111/dmcn.15503. Epub 2023 Jan 17. Dev Med Child Neurol. 2023. PMID: 36649197 Review.
AIM: To identify the research on childhood disability service adaptations and their impact on children and young people with long-term disability during the COVID-19 pandemic. METHOD: A mapping review was undertaken. ...Eligible papers reported service changes for children …
AIM: To identify the research on childhood disability service adaptations and their impact on children and young people with long-term …
CALR-mutated cells are vulnerable to combined inhibition of the proteasome and the endoplasmic reticulum stress response.
Jutzi JS, Marneth AE, Jiménez-Santos MJ, Hem J, Guerra-Moreno A, Rolles B, Bhatt S, Myers SA, Carr SA, Hong Y, Pozdnyakova O, van Galen P, Al-Shahrour F, Nam AS, Mullally A. Jutzi JS, et al. Among authors: carr sa. Leukemia. 2023 Feb;37(2):359-369. doi: 10.1038/s41375-022-01781-0. Epub 2022 Dec 6. Leukemia. 2023. PMID: 36473980
In serial transplantation assays following combined proteasome/IRE1 inhibition for six weeks, we did not find preferential depletion of Calr-mutant long-term HSCs. Together, these findings leverage altered proteostasis in Calr-mutant MPN to identify combinatorial dependenc …
In serial transplantation assays following combined proteasome/IRE1 inhibition for six weeks, we did not find preferential depletion of Calr …
Current status of National Institutes of Health funding for thoracic surgeons in the United States: Beacon of hope or candle in the wind?
Villa Hernandez F, Tolunay UT, Demblowski LA, Wang H, Carr SR, Hoang CD, Choo-Wosoba H, Steinberg SM, Zeiger MA, Schrump DS. Villa Hernandez F, et al. Among authors: carr sr. J Thorac Cardiovasc Surg. 2024 Jan;167(1):271-280.e4. doi: 10.1016/j.jtcvs.2022.10.011. Epub 2022 Oct 15. J Thorac Cardiovasc Surg. 2024. PMID: 36456359
Awards to 5 surgeons accounted for 33% of National Institutes of Health costs for thoracic surgeon principal investigators in 2020; a similar phenomenon was observed for 2010 and 2015. CONCLUSIONS: Long-term structural changes must be implemented to more effectively nurtur …
Awards to 5 surgeons accounted for 33% of National Institutes of Health costs for thoracic surgeon principal investigators in 2020; a simila …
The disease-specific clinical trial network for primary ciliary dyskinesia: PCD-CTN.
Raidt J, Maitre B, Pennekamp P, Altenburg J, Anagnostopoulou P, Armengot M, Bloemsma LD, Boon M, Borrelli M, Brinkmann F, Carr SB, Carroll MP, Castillo-Corullón S, Coste A, Cutrera R, Dehlink E, Destouches DMS, Di Cicco ME, Dixon L, Emiralioglu N, Erdem Eralp E, Haarman EG, Hogg C, Karadag B, Kobbernagel HE, Lorent N, Mall MA, Marthin JK, Martinu V, Narayanan M, Ozcelik U, Peckham D, Pifferi M, Pohunek P, Polverino E, Range S, Ringshausen FC, Robson E, Roehmel J, Rovira-Amigo S, Santamaria F, Schlegtendal A, Szépfalusi Z, Tempels P, Thouvenin G, Ullmann N, Walker WT, Wetzke M, Yiallouros P, Omran H, Nielsen KG. Raidt J, et al. Among authors: carr sb. ERJ Open Res. 2022 Aug 15;8(3):00139-2022. doi: 10.1183/23120541.00139-2022. eCollection 2022 Jul. ERJ Open Res. 2022. PMID: 35983540 Free PMC article.
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