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Patch augmentation surgery for rotator cuff repair: the PARCS mixed-methods feasibility study.
Cook JA, Baldwin M, Cooper C, Nagra NS, Crocker JC, Glaze M, Greenall G, Rangan A, Kottam L, Rees JL, Farrar-Hockley D, Merritt N, Hopewell S, Beard D, Thomas M, Dritsaki M, Carr AJ. Cook JA, et al. Among authors: carr aj. Health Technol Assess. 2021 Feb;25(13):1-138. doi: 10.3310/hta25130. Health Technol Assess. 2021. PMID: 33646096 Free PMC article.
Disease and injury of these tendons can cause significant long-term disability. Early treatment of these tendon problems usually involves painkillers, injections and physiotherapy. ...
Disease and injury of these tendons can cause significant long-term disability. Early treatment of these tendon problems usually invo …
Wrist pain: a systematic review of prevalence and risk factors- what is the role of occupation and activity?
Ferguson R, Riley ND, Wijendra A, Thurley N, Carr AJ, Bjf D. Ferguson R, et al. Among authors: carr aj. BMC Musculoskelet Disord. 2019 Nov 14;20(1):542. doi: 10.1186/s12891-019-2902-8. BMC Musculoskelet Disord. 2019. PMID: 31727033 Free PMC article.
The median prevalence of wrist pain in the general population and non-manual workers within the short term (within last week) was 6 and 4.2% within the medium term (> 1 week and within a year). The median prevalence of wrist pain in physically demanding occupatio …
The median prevalence of wrist pain in the general population and non-manual workers within the short term (within last week) was 6 a …
Injection therapy for base of thumb osteoarthritis: a systematic review and meta-analysis.
Riley N, Vella-Baldacchino M, Thurley N, Hopewell S, Carr AJ, Dean BJF. Riley N, et al. Among authors: carr aj. BMJ Open. 2019 Sep 11;9(9):e027507. doi: 10.1136/bmjopen-2018-027507. BMJ Open. 2019. PMID: 31511280 Free PMC article.
Comparative treatment effects were analysed by random-effects model for short-term and medium-term follow-up. RESULTS: In total, 9 RCTs involving 504 patients were identified for inclusion. ...Meta-analysis of two RCTs (92 patients) demonstrated reduced Visual Analo …
Comparative treatment effects were analysed by random-effects model for short-term and medium-term follow-up. RESULTS: In tota …
Long-term rates of knee arthroplasty in a cohort of 834 393 patients with a history of arthroscopic partial meniscectomy.
Abram SGF, Judge A, Beard DJ, Carr AJ, Price AJ. Abram SGF, et al. Among authors: carr aj. Bone Joint J. 2019 Sep;101-B(9):1071-1080. doi: 10.1302/0301-620X.101B9.BJJ-2019-0335.R1. Bone Joint J. 2019. PMID: 31474146
AIMS: The aim of this study was to determine the long-term risk of undergoing knee arthroplasty in a cohort of patients with meniscal tears who had undergone arthroscopic partial meniscectomy (APM). ...
AIMS: The aim of this study was to determine the long-term risk of undergoing knee arthroplasty in a cohort of patients with meniscal …
Registry stakeholders.
Lübbeke A, Carr AJ, Hoffmeyer P. Lübbeke A, et al. Among authors: carr aj. EFORT Open Rev. 2019 Jun 3;4(6):330-336. doi: 10.1302/2058-5241.4.180077. eCollection 2019 Jun. EFORT Open Rev. 2019. PMID: 31210971 Free PMC article. Review.
Clinical registries are health information systems, which have the mission to collect multidimensional real-world data over the long term, and to generate relevant information and actionable knowledge to address current serious healthcare problems.This article provides an …
Clinical registries are health information systems, which have the mission to collect multidimensional real-world data over the long term …
Cost-effectiveness analysis of a placebo-controlled randomized trial evaluating the effectiveness of arthroscopic subacromial decompression in patients with subacromial shoulder pain.
Rombach I, Merritt N, Shirkey BA, Rees JL, Cook JA, Cooper C, Carr AJ, Beard DJ, Gray AM. Rombach I, et al. Among authors: carr aj. Bone Joint J. 2019 Jan;101-B(1):55-62. doi: 10.1302/0301-620X.101B1.BJJ-2018-0555.R1. Bone Joint J. 2019. PMID: 30601058 Free article. Clinical Trial.
DISCUSSION: The evidence for cost-effectiveness at 12 months was inconclusive. Decompression could be cost-effective in the longer-term, but results of this analysis are sensitive to the assumptions made about how costs and QALYs are extrapolated beyond the follow-up of th …
DISCUSSION: The evidence for cost-effectiveness at 12 months was inconclusive. Decompression could be cost-effective in the longer-term …
Phase 1 clinical study of an embryonic stem cell-derived retinal pigment epithelium patch in age-related macular degeneration.
da Cruz L, Fynes K, Georgiadis O, Kerby J, Luo YH, Ahmado A, Vernon A, Daniels JT, Nommiste B, Hasan SM, Gooljar SB, Carr AF, Vugler A, Ramsden CM, Bictash M, Fenster M, Steer J, Harbinson T, Wilbrey A, Tufail A, Feng G, Whitlock M, Robson AG, Holder GE, Sagoo MS, Loudon PT, Whiting P, Coffey PJ. da Cruz L, et al. Nat Biotechnol. 2018 Apr;36(4):328-337. doi: 10.1038/nbt.4114. Epub 2018 Mar 19. Nat Biotechnol. 2018. PMID: 29553577 Free article. Clinical Trial.
We report successful delivery and survival of the RPE patch by biomicroscopy and optical coherence tomography, and a visual acuity gain of 29 and 21 letters in the two patients, respectively, over 12 months. Only local immunosuppression was used long-term. We also present …
We report successful delivery and survival of the RPE patch by biomicroscopy and optical coherence tomography, and a visual acuity gain of 2 …
The Use of Electrospun Scaffolds in Musculoskeletal Tissue Engineering: A Focus on Tendon and the Rotator Cuff.
Stace ET, Nagra NS, Tiberwel S, Khan W, Carr AJ. Stace ET, et al. Among authors: carr aj. Curr Stem Cell Res Ther. 2018;13(8):619-631. doi: 10.2174/1574888X13666180129105707. Curr Stem Cell Res Ther. 2018. PMID: 29380705 Review.
Current operative techniques and repair adjuncts are associated with unacceptably high failure rates, stimulating investigation into novel tissue engineering and regenerative medicine (TERM) approaches in the field of rotator cuff surgery. In this review we explore the mos …
Current operative techniques and repair adjuncts are associated with unacceptably high failure rates, stimulating investigation into novel t …
Past and projected temporal trends in arthroscopic hip surgery in England between 2002 and 2013.
Palmer AJ, Malak TT, Broomfield J, Holton J, Majkowski L, Thomas GE, Taylor A, Andrade AJ, Collins G, Watson K, Carr AJ, Glyn-Jones S. Palmer AJ, et al. Among authors: carr aj. BMJ Open Sport Exerc Med. 2016 Mar 21;2(1):e000082. doi: 10.1136/bmjsem-2015-000082. eCollection 2016. BMJ Open Sport Exerc Med. 2016. PMID: 27900161 Free PMC article.
Studies from USA demonstrate a 365% increase in the number of procedures performed between 2004 and 2009 and 250% increase between 2007 and 2011. There is limited evidence of long-term efficacy for this procedure and hip arthroscopy is not universally funded across England …
Studies from USA demonstrate a 365% increase in the number of procedures performed between 2004 and 2009 and 250% increase between 2007 and …
The Effects of Glucocorticoid on Tendon and Tendon Derived Cells.
Dean BJ, Carr AJ. Dean BJ, et al. Among authors: carr aj. Adv Exp Med Biol. 2016;920:239-46. doi: 10.1007/978-3-319-33943-6_23. Adv Exp Med Biol. 2016. PMID: 27535266 Review.
Overall the existing in vitro and in vivo evidence suggests that glucocorticoids should be used with caution in treating painful tendinopathy. Certainly a real need exists to follow up the long term clinical effects of glucocorticoid in treating tendinopathy, as there is c …
Overall the existing in vitro and in vivo evidence suggests that glucocorticoids should be used with caution in treating painful tendinopath …
31 results