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Associations of rs3918242 and rs2285053 MMP-9 and MMP-2 polymorphisms with the risk, severity, and short- and long-term complications of degenerative mitral valve diseases: a 4.8-year prospective cohort study.
Balistreri CR, Allegra A, Crapanzano F, Pisano C, Triolo OF, Argano V, Candore G, Lio D, Ruvolo G. Balistreri CR, et al. Among authors: candore g. Cardiovasc Pathol. 2016 Sep-Oct;25(5):362-70. doi: 10.1016/j.carpath.2016.05.004. Epub 2016 May 20. Cardiovasc Pathol. 2016. PMID: 27288746
Thus, we performed for the first time a perspective study to assess eventual associations of some functional single nucleotide polymorphisms (SNPs) in MMP-2 and MMP-9 genes with the MVD risk, symptom severity, and short- and long-term (4.8 years) complications. MATERIALS A …
Thus, we performed for the first time a perspective study to assess eventual associations of some functional single nucleotide polymorphisms …
Immunosenescence, inflammation and Alzheimer's disease.
Martorana A, Bulati M, Buffa S, Pellicanò M, Caruso C, Candore G, Colonna-Romano G. Martorana A, et al. Among authors: candore g. Longev Healthspan. 2012 Nov 1;1:8. doi: 10.1186/2046-2395-1-8. eCollection 2012. Longev Healthspan. 2012. PMID: 24764513 Free PMC article. Review.
On the other hand, ageing is also characterized by "inflamm-ageing", a term coined to explain the inflammation commonly present in many age-associated diseases. ...
On the other hand, ageing is also characterized by "inflamm-ageing", a term coined to explain the inflammation commonly present in ma …
Mechanisms of immunosenescence.
Caruso C, Buffa S, Candore G, Colonna-Romano G, Dunn-Walters D, Kipling D, Pawelec G. Caruso C, et al. Among authors: candore g. Immun Ageing. 2009 Jul 22;6:10. doi: 10.1186/1742-4933-6-10. Immun Ageing. 2009. PMID: 19624841 Free PMC article.
Alterations to the immune system in the older person are generally viewed as a deterioration of immunity, leading to the use of the catch-all term immunosenescence. Indeed, many immunological parameters are often markedly different in elderly compared to young people, and …
Alterations to the immune system in the older person are generally viewed as a deterioration of immunity, leading to the use of the catch-al …
Association between HFE mutations and acute myocardial infarction: a study in patients from Northern and Southern Italy.
Candore G, Balistreri CR, Lio D, Mantovani V, Colonna-Romano G, Chiappelli M, Tampieri C, Licastro F, Branzi A, Averna M, Caruso M, Hoffmann E, Caruso C. Candore G, et al. Blood Cells Mol Dis. 2003 Jul-Aug;31(1):57-62. doi: 10.1016/s1079-9796(03)00065-2. Blood Cells Mol Dis. 2003. PMID: 12850485
These studies have possible confounding factors, such as the homogeneity of the population in term of geographical origin among others. We studied the relation between HFE mutations and acute myocardial infarction in two case-control studies involving two sets of subjects …
These studies have possible confounding factors, such as the homogeneity of the population in term of geographical origin among other …
IL-10 and TNF-alpha polymorphisms and the recovery from HCV infection.
Lio D, Caruso C, Di Stefano R, Colonna Romano G, Ferraro D, Scola L, Crivello A, Licata A, Valenza LM, Candore G, Craxì A, Almasio PL. Lio D, et al. Among authors: candore g. Hum Immunol. 2003 Jul;64(7):674-80. doi: 10.1016/s0198-8859(03)00080-6. Hum Immunol. 2003. PMID: 12826369
It is conceivable that the host immunogenetic background influences the course of infection in term of recovery. Thus, in this study we have evaluated the effect of functionally relevant polymorphisms at tumor necrosis factor-alpha (TNF-alpha, i.e., 2 biallelic polymorphis …
It is conceivable that the host immunogenetic background influences the course of infection in term of recovery. Thus, in this study …
Association between the HLA-DR alleles and longevity: a study in Sardinian population.
Lio D, Pes GM, Carru C, Listì F, Ferlazzo V, Candore G, Colonna-Romano G, Ferrucci L, Deiana L, Baggio G, Franceschi C, Caruso C. Lio D, et al. Among authors: candore g. Exp Gerontol. 2003 Mar;38(3):313-7. doi: 10.1016/s0531-5565(02)00178-x. Exp Gerontol. 2003. PMID: 12581796
Association studies are subjected to a number of possible confounding factors, the homogeneity of the population in term of geographical origin among others. Because of the lack of large-scale heterogeneity, the Sardinians represent a suitable population for association st …
Association studies are subjected to a number of possible confounding factors, the homogeneity of the population in term of geographi …
In vitro treatment with interleukin-2 normalizes type-1 cytokine production by lymphocytes from elderly.
Lio D, Balistreri CR, Candore G, D'Anna C, Di Lorenzo G, Gervasi F, Listì F, Scola L, Caruso C. Lio D, et al. Among authors: candore g. Immunopharmacol Immunotoxicol. 2000 May;22(2):195-203. doi: 10.3109/08923970009016415. Immunopharmacol Immunotoxicol. 2000. PMID: 10952026
The term immunosenescence is taken to mean the deterioration of immune function seen in elderly, which is manifested in increased susceptibility to infectious diseases, neoplasias, and autoimmune diseases. ...
The term immunosenescence is taken to mean the deterioration of immune function seen in elderly, which is manifested in increased sus …