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Page 1
Pulmonary aspergillosis: diagnosis and treatment.
Lamoth F, Calandra T. Lamoth F, et al. Among authors: calandra t. Eur Respir Rev. 2022 Nov 29;31(166):220114. doi: 10.1183/16000617.0114-2022. Print 2022 Dec 31. Eur Respir Rev. 2022. PMID: 36450372 Free PMC article.
CPA mainly affects patients with pre-existing lung lesions and is recognised increasingly frequently among patients with long-term survival following cure of tuberculosis or lung cancer. The diagnosis of pulmonary aspergillosis is complex as it relies on the presence of cl …
CPA mainly affects patients with pre-existing lung lesions and is recognised increasingly frequently among patients with long-term su …
A placebo-controlled trial of oral fingolimod in relapsing multiple sclerosis.
Kappos L, Radue EW, O'Connor P, Polman C, Hohlfeld R, Calabresi P, Selmaj K, Agoropoulou C, Leyk M, Zhang-Auberson L, Burtin P; FREEDOMS Study Group. Kappos L, et al. N Engl J Med. 2010 Feb 4;362(5):387-401. doi: 10.1056/NEJMoa0909494. Epub 2010 Jan 20. N Engl J Med. 2010. PMID: 20089952 Free article. Clinical Trial.
These benefits will need to be weighed against possible long-term risks. (ClinicalTrials.gov number, NCT00289978.)...
These benefits will need to be weighed against possible long-term risks. (ClinicalTrials.gov number, NCT00289978.)...
Early diagnosis of invasive mould infections and disease.
Lamoth F, Calandra T. Lamoth F, et al. Among authors: calandra t. J Antimicrob Chemother. 2017 Mar 1;72(suppl_1):i19-i28. doi: 10.1093/jac/dkx030. J Antimicrob Chemother. 2017. PMID: 28355464 Review.
Invasive mould infections (IMIs), such as invasive aspergillosis or mucormycosis, are a major cause of death in patients with haematological cancer and in patients receiving long-term immunosuppressive therapy. Early diagnosis and prompt initiation of antifungal therapy ar …
Invasive mould infections (IMIs), such as invasive aspergillosis or mucormycosis, are a major cause of death in patients with haematological …
Understanding and Enhancing Sepsis Survivorship. Priorities for Research and Practice.
Prescott HC, Iwashyna TJ, Blackwood B, Calandra T, Chlan LL, Choong K, Connolly B, Dark P, Ferrucci L, Finfer S, Girard TD, Hodgson C, Hopkins RO, Hough CL, Jackson JC, Machado FR, Marshall JC, Misak C, Needham DM, Panigrahi P, Reinhart K, Yende S, Zafonte R, Rowan KM, Angus DC. Prescott HC, et al. Among authors: calandra t. Am J Respir Crit Care Med. 2019 Oct 15;200(8):972-981. doi: 10.1164/rccm.201812-2383CP. Am J Respir Crit Care Med. 2019. PMID: 31161771 Free PMC article.
However, clinical trials and guidelines have focused on shorter-term survival, so there are few data on promoting longer-term recovery. ...The top longer-term priorities were to study mechanisms of long-term morbidity through large cohort studies with …
However, clinical trials and guidelines have focused on shorter-term survival, so there are few data on promoting longer-term
Bacteremia due to viridans streptococci in neutropenic patients: a review.
Bochud PY, Calandra T, Francioli P. Bochud PY, et al. Among authors: calandra t. Am J Med. 1994 Sep;97(3):256-64. doi: 10.1016/0002-9343(94)90009-4. Am J Med. 1994. PMID: 8092175 Review.
The introduction of penicillin in prophylactic antibiotic treatments has reduced the incidence of these infections, but the long-term use of penicillin could be compromised by the emergence of resistant strains....
The introduction of penicillin in prophylactic antibiotic treatments has reduced the incidence of these infections, but the long-term
Outcome measures for clinical research in sepsis: a report of the 2nd Cambridge Colloquium of the International Sepsis Forum.
Marshall JC, Vincent JL, Guyatt G, Angus DC, Abraham E, Bernard G, Bombardier C, Calandra T, Jørgensen HS, Sylvester R, Boers M. Marshall JC, et al. Among authors: calandra t. Crit Care Med. 2005 Aug;33(8):1708-16. doi: 10.1097/01.ccm.0000174478.70338.03. Crit Care Med. 2005. PMID: 16096445 Review.
After in vivo biology has been demonstrated and the possibility of efficacy inferred by plausible improvements in surrogate physiologic measures, definitive studies should seek robust evidence of benefit using end points that measure important, patient-centered benefit, including …
After in vivo biology has been demonstrated and the possibility of efficacy inferred by plausible improvements in surrogate physiologic meas …
Trends of the Epidemiology of Candidemia in Switzerland: A 15-Year FUNGINOS Survey.
Adam KM, Osthoff M, Lamoth F, Conen A, Erard V, Boggian K, Schreiber PW, Zimmerli S, Bochud PY, Neofytos D, Fleury M, Fankhauser H, Goldenberger D, Mühlethaler K, Riat A, Zbinden R, Kronenberg A, Quiblier C, Marchetti O, Khanna N; Fungal Infection Network of Switzerland (FUNGINOS). Adam KM, et al. Open Forum Infect Dis. 2021 Sep 17;8(10):ofab471. doi: 10.1093/ofid/ofab471. eCollection 2021 Oct. Open Forum Infect Dis. 2021. PMID: 34660836 Free PMC article.
BACKGROUND: The increasing incidence of candidemia and emergence of drug-resistant Candida species are major concerns worldwide. Long-term surveillance studies are needed. METHODS: The Fungal Infection Network of Switzerland (FUNGINOS) conducted a 15-year (2004-2018), nati …
BACKGROUND: The increasing incidence of candidemia and emergence of drug-resistant Candida species are major concerns worldwide. Long-ter
IRF5 Is a Key Regulator of Macrophage Response to Lipopolysaccharide in Newborns.
Schneider A, Weier M, Herderschee J, Perreau M, Calandra T, Roger T, Giannoni E. Schneider A, et al. Among authors: calandra t. Front Immunol. 2018 Jul 11;9:1597. doi: 10.3389/fimmu.2018.01597. eCollection 2018. Front Immunol. 2018. PMID: 30050534 Free PMC article.
The purpose of this study was to characterize differences in monocyte to macrophage differentiation and polarization between newborns and adults. Monocytes from umbilical cord blood of healthy term newborns and from peripheral blood of adult healthy subjects were exposed t …
The purpose of this study was to characterize differences in monocyte to macrophage differentiation and polarization between newborns and ad …
Impact of fingolimod therapy on magnetic resonance imaging outcomes in patients with multiple sclerosis.
Radue EW, O'Connor P, Polman CH, Hohlfeld R, Calabresi P, Selmaj K, Mueller-Lenke N, Agoropoulou C, Holdbrook F, de Vera A, Zhang-Auberson L, Francis G, Burtin P, Kappos L; FTY720 Research Evaluating Effects of Daily Oral Therapy in Multiple Sclerosis (FREEDOMS) Study Group. Radue EW, et al. Arch Neurol. 2012 Oct;69(10):1259-69. doi: 10.1001/archneurol.2012.1051. Arch Neurol. 2012. PMID: 22751847 Clinical Trial.
CONCLUSION: These results, coupled with the significant reductions in relapse rates and disability progression reported previously, support the positive impact on long-term disease evolution. TRIAL REGISTRATION: clinicaltrials.gov Identifier: NCT00289978...
CONCLUSION: These results, coupled with the significant reductions in relapse rates and disability progression reported previously, support …