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Stimulation of cell proliferation and inhibition of gap junctional intercellular communication by linoleic acid.
Hayashi T, Matesic DF, Nomata K, Kang KS, Chang CC, Trosko JE. Hayashi T, et al. Cancer Lett. 1997 Jan 15;112(1):103-11. doi: 10.1016/S0304-3835(96)04553-3. Cancer Lett. 1997. PMID: 9029175
Addition of linoleic acid (0.01-3 mg/ml) to the low serum medium increased the growth rate and inhibited gap junctional intercellular communication (GJIC) in a dose-dependent manner. In a comparison of short-term and long-term treatments with LA, GJIC in short-te …
Addition of linoleic acid (0.01-3 mg/ml) to the low serum medium increased the growth rate and inhibited gap junctional intercellular commun …
Stem cell theory of carcinogenesis.
Trosko JE, Chang CC. Trosko JE, et al. Toxicol Lett. 1989 Dec;49(2-3):283-95. doi: 10.1016/0378-4274(89)90038-6. Toxicol Lett. 1989. PMID: 2690407 Review.
This understanding, plus recent results of the National Toxicology Bioassay program and of the studies of short-term tests for genotoxicity, has challenged the primary paradigm of 'carcinogens as mutagens' which governs our current risk assessment models. ...
This understanding, plus recent results of the National Toxicology Bioassay program and of the studies of short-term tests for genoto …
Characteristics of long-term human epithelial cell cultures derived from normal human fetal kidney.
Gibson-D'Ambrosio RE, Samuel M, Chang CC, Trosko JE, D'Ambrosio SM. Gibson-D'Ambrosio RE, et al. In Vitro Cell Dev Biol. 1987 Apr;23(4):279-87. doi: 10.1007/BF02623711. In Vitro Cell Dev Biol. 1987. PMID: 2437097
Epithelial cell cultures were prepared from normal human fetal kidney and established in long-term culture. The growth characteristics and production of keratin, and alkaline phosphatase (AP) and gamma-glutamyl transpeptidase (GGT) activities were compared in a modified mi …
Epithelial cell cultures were prepared from normal human fetal kidney and established in long-term culture. The growth characteristic …