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Genetic and multi-omic risk assessment of Alzheimer's disease implicates core associated biological domains.
Cary GA, Wiley JC, Gockley J, Keegan S, Amirtha Ganesh SS, Heath L, Butler RR 3rd, Mangravite LM, Logsdon BA, Longo FM, Levey A, Greenwood AK, Carter GW. Cary GA, et al. Among authors: butler rr 3rd. Alzheimers Dement (N Y). 2024 Apr 22;10(2):e12461. doi: 10.1002/trc2.12461. eCollection 2024 Apr-Jun. Alzheimers Dement (N Y). 2024. PMID: 38650747 Free PMC article.
The biological domains are constructed from exhaustive Gene Ontology (GO) term compilations, allowing automated assignment of genes into objectively defined disease-associated biology. ...
The biological domains are constructed from exhaustive Gene Ontology (GO) term compilations, allowing automated assignment of genes i …
Active contact proximity to the cerebellothalamic tract predicts initial therapeutic current requirement with DBS for ET: an application of 7T MRI.
Ikramuddin SS, Brinda AK, Butler RD, Hill ME, Dharnipragada R, Aman JE, Schrock LE, Cooper SE, Palnitkar T, Patriat R, Harel N, Vitek JL, Johnson MD. Ikramuddin SS, et al. Among authors: butler rd. Front Neurol. 2023 Nov 9;14:1258895. doi: 10.3389/fneur.2023.1258895. eCollection 2023. Front Neurol. 2023. PMID: 38020603 Free PMC article.
Active contact distance to the CTT did not predict post-operative tremor control at the time of the longer term clinical follow up (R(2) = -0.073, p = 0.58). CONCLUSION: Active DBS contact proximity to the CTT was associated with lower therapeutic current requirement follo …
Active contact distance to the CTT did not predict post-operative tremor control at the time of the longer term clinical follow up (R …
Surgical Options for the Treatment of Perianal and Anovaginal Fistulas in the Setting of Ileoanal Pouch Crohn's Disease: Experience of a Tertiary Center.
Otero-Piñeiro AM, Hull T, Holubar S, Pedersen KE, Aykun N, Obi M, Butler R, Steele SR, Lightner AL. Otero-Piñeiro AM, et al. Among authors: butler r. J Gastrointest Surg. 2023 Dec;27(12):2867-2875. doi: 10.1007/s11605-023-05603-1. Epub 2023 Nov 20. J Gastrointest Surg. 2023. PMID: 37985619
LIMITATIONS: Retrospective single-center study which lacks a control arm and consistent long-term follow-up specific to a population-based dataset. CONCLUSIONS: Pouch patients who develop perianal disease are difficult to treat, sometimes requiring pouch excision. ...
LIMITATIONS: Retrospective single-center study which lacks a control arm and consistent long-term follow-up specific to a population- …
P2Y6 Receptor-Dependent Microglial Phagocytosis of Synapses during Development Regulates Synapse Density and Memory.
Dundee JM, Puigdellívol M, Butler R, Brown GC. Dundee JM, et al. Among authors: butler r. J Neurosci. 2023 Nov 29;43(48):8090-8103. doi: 10.1523/JNEUROSCI.1089-23.2023. J Neurosci. 2023. PMID: 37758475
We also show that adult P2Y(6)R KO mice have impaired short- and long-term spatial memory and impaired short- and long-term recognition memory compared with WT mice, as measured by novel location recognition, novel object recognition, and Y-maze memory tests. ...
We also show that adult P2Y(6)R KO mice have impaired short- and long-term spatial memory and impaired short- and long-term re …
Analysis of shared underlying mechanism in neurodegenerative disease.
Butler R, Bradford D, Rodgers KE. Butler R, et al. Front Aging Neurosci. 2022 Nov 29;14:1006089. doi: 10.3389/fnagi.2022.1006089. eCollection 2022. Front Aging Neurosci. 2022. PMID: 36523957 Free PMC article. Review.
In this review, the relationship between bioenergetics, mitochondrial dysfunction, and inflammation will be and how they contribute to neurodegeneration, specifically in Alzheimer's disease (AD), amyotrophic lateral sclerosis (ALS), and multiple sclerosis (MS) will be reviewed. L …
In this review, the relationship between bioenergetics, mitochondrial dysfunction, and inflammation will be and how they contribute to neuro …
Post-infarction ventricular septal defect: percutaneous or surgical management in the UK national registry.
Giblett JP, Matetic A, Jenkins D, Ng CY, Venuraju S, MacCarthy T, Vibhishanan J, O'Neill JP, Kirmani BH, Pullan DM, Stables RH, Andrews J, Buttinger N, Kim WC, Kanyal R, Butler MA, Butler R, George S, Khurana A, Crossland DS, Marczak J, Smith WHT, Thomson JDR, Bentham JR, Clapp BR, Buch M, Hayes N, Byrne J, MacCarthy P, Aggarwal SK, Shapiro LM, Turner MS, de Giovanni J, Northridge DB, Hildick-Smith D, Mamas MA, Calvert PA. Giblett JP, et al. Among authors: butler r. Eur Heart J. 2022 Dec 21;43(48):5020-5032. doi: 10.1093/eurheartj/ehac511. Eur Heart J. 2022. PMID: 36124729
Case note review was undertaken. The primary outcome was long-term mortality. Patient groups were allocated based upon initial management (percutaneous or surgical). ...There was no difference in post-discharge long-term mortality between patients, although in-hospi …
Case note review was undertaken. The primary outcome was long-term mortality. Patient groups were allocated based upon initial manage …
Colour Response in Western Flower Thrips Varies Intraspecifically.
Lopez-Reyes K, Armstrong KF, Teulon DAJ, Butler RC, van Dooremalen C, Roher M, van Tol RWHM. Lopez-Reyes K, et al. Among authors: butler rc. Insects. 2022 Jun 10;13(6):538. doi: 10.3390/insects13060538. Insects. 2022. PMID: 35735875 Free PMC article.
Results suggest that differing responses of WFT populations to colour is, in this case, independent of the experimental situation. Long-term separate isolation from the wild cannot be excluded as a cause, and the implications of this for optimising the trap colour is discu …
Results suggest that differing responses of WFT populations to colour is, in this case, independent of the experimental situation. Long-t …
Nutrition-Related Information Shared by Latine Influencers: A YouTube Content Analysis.
Clark L, Lopez ED, Woods L, Yockey A, Butler R, Barroso CS. Clark L, et al. Among authors: butler r. Health Promot Pract. 2023 Jul;24(4):713-722. doi: 10.1177/15248399221083302. Epub 2022 Apr 6. Health Promot Pract. 2023. PMID: 35382623
Latines are the fastest growing populace in the United States. Latine is a new, inclusive term for Hispanic and Latino populations regardless of gender identity. ...
Latines are the fastest growing populace in the United States. Latine is a new, inclusive term for Hispanic and Latino populations re …
Biodiversity across space and time in the fossil record.
Benson RBJ, Butler R, Close RA, Saupe E, Rabosky DL. Benson RBJ, et al. Among authors: butler r. Curr Biol. 2021 Oct 11;31(19):R1225-R1236. doi: 10.1016/j.cub.2021.07.071. Curr Biol. 2021. PMID: 34637736 Free article. Review.
The fossil record is the primary source of information on how biodiversity has varied in deep time, providing unique insight on the long-term dynamics of diversification and their drivers. However, interpretations of fossil record diversity patterns have been much debated, …
The fossil record is the primary source of information on how biodiversity has varied in deep time, providing unique insight on the long- …
107 results