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Sex differences in thromboprophylaxis of the critically ill: a secondary analysis of a randomized trial.
Burns KEA, Heels-Ansdell D, Thabane L, Kahn SR, Lauzier F, Mehta S, Ostermann M, Bhuptani P, Crowther MA, Finfer S, Cook DJ; PROTECT Investigators, the Canadian Critical Care Trials Group, and the Australian and New Zealand Intensive Care Society Clinical Trials Group. Burns KEA, et al. Can J Anaesth. 2023 Jun;70(6):1008-1018. doi: 10.1007/s12630-023-02457-8. Epub 2023 Jun 13. Can J Anaesth. 2023. PMID: 37310606 Clinical Trial. English.
METHODS: We conducted unadjusted analyses using Cox proportional hazards analysis, stratified by centre and admission diagnostic category, including sex, treatment, and an interaction term. Additionally, we performed adjusted analyses and assessed the credibility of our fi …
METHODS: We conducted unadjusted analyses using Cox proportional hazards analysis, stratified by centre and admission diagnostic category, i …
Study protocol for a randomized controlled trial of Proportional Assist Ventilation for Minimizing the Duration of Mechanical Ventilation: the PROMIZING study.
Bosma KJ, Martin CM, Burns KEA, Mancebo Cortes J, Suárez Montero JC, Skrobik Y, Thorpe KE, Amaral ACK, Arabi Y, Basmaji J, Beduneau G, Beloncle F, Carteaux G, Charbonney E, Demoule A, Dres M, Fanelli V, Geagea A, Goligher E, Lellouche F, Maraffi T, Mercat A, Rodriguez PO, Shahin J, Sibley S, Spadaro S, Vaporidi K, Wilcox ME, Brochard L; Canadian Critical Care Trials Group and; REVA Network. Bosma KJ, et al. Among authors: burns kea. Trials. 2023 Mar 27;24(1):232. doi: 10.1186/s13063-023-07163-w. Trials. 2023. PMID: 36973743 Free PMC article.
The proportional assistance, called the gain, can be adjusted by the clinician to maintain the patient's respiratory effort or workload within a normal range. Short-term and physiological benefits of this mode compared to pressure support ventilation (PSV) include better p …
The proportional assistance, called the gain, can be adjusted by the clinician to maintain the patient's respiratory effort or workload with …
Haemoglobin transfusion threshold in traumatic brain injury optimisation (HEMOTION): a multicentre, randomised, clinical trial protocol.
Turgeon AF, Fergusson DA, Clayton L, Patton MP, Zarychanski R, English S, Docherty A, Walsh T, Griesdale D, Kramer AH, Scales D, Burns KEA, Boyd JG, Marshall JC, Kutsogiannis DJ, Ball I, Hébert PC, Lamontagne F, Costerousse O, St-Onge M, Lessard Bonaventure P, Moore L, Neveu X, Rigamonti A, Khwaja K, Green RS, Laroche V, Fox-Robichaud A, Lauzier F; HEMOTION Trial Team, the Canadian Critical Care Trials Group, the Canadian Perioperative Anesthesia Clinical Trials Group and the Canadian Traumatic Brain Injury Research Consortium. Turgeon AF, et al. Among authors: burns kea. BMJ Open. 2022 Oct 10;12(10):e067117. doi: 10.1136/bmjopen-2022-067117. BMJ Open. 2022. PMID: 36216432 Free PMC article.
INTRODUCTION: Traumatic brain injury (TBI) is the leading cause of mortality and long-term disability in young adults. Despite the high prevalence of anaemia and red blood cell transfusion in patients with TBI, the optimal haemoglobin (Hb) transfusion threshold is unknown. …
INTRODUCTION: Traumatic brain injury (TBI) is the leading cause of mortality and long-term disability in young adults. Despite the hi …
Noninvasive respiratory support following extubation in critically ill adults: a systematic review and network meta-analysis.
Fernando SM, Tran A, Sadeghirad B, Burns KEA, Fan E, Brodie D, Munshi L, Goligher EC, Cook DJ, Fowler RA, Herridge MS, Cardinal P, Jaber S, Møller MH, Thille AW, Ferguson ND, Slutsky AS, Brochard LJ, Seely AJE, Rochwerg B. Fernando SM, et al. Among authors: burns kea. Intensive Care Med. 2022 Feb;48(2):137-147. doi: 10.1007/s00134-021-06581-1. Epub 2021 Nov 25. Intensive Care Med. 2022. PMID: 34825256 Free article.
Compared to conventional oxygen therapy, neither NIPPV (OR 0.8 [95% CI 0.61-1.04], moderate certainty) or HFNC (OR 0.9 [95% CI 0.66-1.24], low certainty) reduced short-term mortality. Consistent findings were demonstrated across multiple subgroups, including high- and low- …
Compared to conventional oxygen therapy, neither NIPPV (OR 0.8 [95% CI 0.61-1.04], moderate certainty) or HFNC (OR 0.9 [95% CI 0.66-1.24], l …
Short-and long-term outcomes of sustained low efficiency dialysis vs continuous renal replacement therapy in critically ill patients with acute kidney injury.
Harvey AK, Burns KEA, McArthur E, Adhikari NKJ, Li D, Kitchlu A, Meraz-Munõz A, Garg AX, Nash DM, Perez-Sanchez A, Beaubien-Souligny W, Bagshaw SM, Friedrich JO, Silver SA, Wald R. Harvey AK, et al. Among authors: burns kea. J Crit Care. 2021 Apr;62:76-81. doi: 10.1016/j.jcrc.2020.11.003. Epub 2020 Nov 22. J Crit Care. 2021. PMID: 33290929
However, there is limited information on the short- and long-term outcomes of SLED compared to CRRT. METHODS: We conducted a retrospective cohort study of patients with AKI who commenced either SLED or CRRT in ICUs at a tertiary care hospital in Toronto, Canada. ...
However, there is limited information on the short- and long-term outcomes of SLED compared to CRRT. METHODS: We conducted a retrospe …
The role of non-invasive ventilation in weaning and decannulating critically ill patients with tracheostomy: A narrative review of the literature.
Guia M, Ciobanu LD, Sreedharan JK, Abdelrahim ME, Gonçalves G, Cabrita B, Alqahtani JS, Duan J, El-Khatib M, Diaz-Abad M, Wittenstein J, Karim HMR, Bhakta P, Ruggeri P, Garuti G, Burns KEA, Soo Hoo GW, Scala R, Esquinas A; International Association of Non Invasive Ventilation. Guia M, et al. Among authors: burns kea. Pulmonology. 2021 Jan-Feb;27(1):43-51. doi: 10.1016/j.pulmoe.2020.07.002. Epub 2020 Jul 25. Pulmonology. 2021. PMID: 32723618 Free article. Review.
INTRODUCTION: Invasive mechanical ventilation (IMV) is associated with several complications. Placement of a long-term airway (tracheostomy) is also associated with short and long-term risks for patients. ...
INTRODUCTION: Invasive mechanical ventilation (IMV) is associated with several complications. Placement of a long-term airway (trache …
Moderate Certainty Evidence Suggests the Use of High-Flow Nasal Cannula Does Not Decrease Hypoxia When Compared With Conventional Oxygen Therapy in the Peri-Intubation Period: Results of a Systematic Review and Meta-Analysis.
Chaudhuri D, Granton D, Wang DX, Einav S, Helviz Y, Mauri T, Ricard JD, Mancebo J, Frat JP, Jog S, Hernandez G, Maggiore SM, Hodgson C, Jaber S, Brochard L, Burns KEA, Rochwerg B. Chaudhuri D, et al. Among authors: burns kea. Crit Care Med. 2020 Apr;48(4):571-578. doi: 10.1097/CCM.0000000000004217. Crit Care Med. 2020. PMID: 32205604
Secondary outcomes included peri-intubation complications, apneic time, PaO2 before and after intubation, PaCO2 after intubation, ICU length of stay, and short-term mortality. DATA SYNTHESIS: We included 10 randomized clinical trials (n = 1,017 patients). ...
Secondary outcomes included peri-intubation complications, apneic time, PaO2 before and after intubation, PaCO2 after intubation, ICU length …
Noninvasive ventilation: education and training. A narrative analysis and an international consensus document.
Karim HMR, Burns KEA, Ciobanu LD, El-Khatib M, Nicolini A, Vargas N, Hernández-Gilsoul T, Skoczyński S, Falcone VA, Arnal JM, Bach J, De Santo LS, Lucchini A, Steier J, Purro A, Petroianni A, Sassoon CS, Bambi S, Aguiar M, Soubani AO, Taniguchi C, Mollica C, Berlin DA, Piervincenzi E, Rao F, Luigi FS, Ferrari R, Garuti G, Laier-Groeneveld G, Fiorentino G, Ho KM, Alqahtani JS, Luján M, Moerer O, Resta O, Pierucci P, Papadakos P, Steiner S, Stieglitz S, Dikmen Y, Duan J, Bhakta P, Iglesias AU, Corcione N, Caldeira V, Karakurt Z, Valli G, Kondili E, Ruggieri MP, Raposo MS, Bottino F, Soler-González R, Gurjar M, Sandoval-Gutierrez JL, Jafari B, Arroyo-Cozar M, Noval AR, Corcione N, Barjaktarevic I, Sarc I, Mina B, Szkulmowski Z, Taniguchi C, Esquinas AM. Karim HMR, et al. Among authors: burns kea. Adv Respir Med. 2019;87(1):36-45. doi: 10.5603/ARM.a2019.0006. Epub 2019 Mar 4. Adv Respir Med. 2019. PMID: 30830962 Free article.
The use of NIV is expanding over the time and if properly applied, it can save patients' lives and improve long-term prognosis. However, both knowledge and skills of its proper use as life support are paramount. ...
The use of NIV is expanding over the time and if properly applied, it can save patients' lives and improve long-term prognosis. Howev …
Long-Term Outcomes and Health Care Utilization after Prolonged Mechanical Ventilation.
Hill AD, Fowler RA, Burns KE, Rose L, Pinto RL, Scales DC. Hill AD, et al. Ann Am Thorac Soc. 2017 Mar;14(3):355-362. doi: 10.1513/AnnalsATS.201610-792OC. Ann Am Thorac Soc. 2017. PMID: 28033033
RATIONALE: Limited data are available to characterize the long-term outcomes and associated costs for patients who require prolonged mechanical ventilation (PMV; defined here as mechanical ventilation for longer than 21 d). ...
RATIONALE: Limited data are available to characterize the long-term outcomes and associated costs for patients who require prolonged …
Changing incidence and outcomes following dialysis-requiring acute kidney injury among critically ill adults: a population-based cohort study.
Wald R, McArthur E, Adhikari NK, Bagshaw SM, Burns KE, Garg AX, Harel Z, Kitchlu A, Mazer CD, Nash DM, Scales DC, Silver SA, Ray JG, Friedrich JO. Wald R, et al. Am J Kidney Dis. 2015 Jun;65(6):870-7. doi: 10.1053/j.ajkd.2014.10.017. Epub 2014 Dec 18. Am J Kidney Dis. 2015. PMID: 25533599
This was accompanied by a significant decline in mortality, but the risk of long-term dialysis dependence continues to affect a substantial minority of surviving patients with no clear evidence of improvement over time....
This was accompanied by a significant decline in mortality, but the risk of long-term dialysis dependence continues to affect a subst …
14 results