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NCCN Guidelines® Insights: Hodgkin Lymphoma, Version 2.2022.
Hoppe RT, Advani RH, Ai WZ, Ambinder RF, Armand P, Bello CM, Benitez CM, Chen W, Dabaja B, Daly ME, Gordon LI, Hansen N, Herrera AF, Hochberg EP, Johnston PB, Kaminski MS, Kelsey CR, Kenkre VP, Khan N, Lynch RC, Maddocks K, McConathy J, Metzger M, Morgan D, Mulroney C, Pullarkat ST, Rabinovitch R, Rosenspire KC, Seropian S, Tao R, Torka P, Winter JN, Yahalom J, Yang JC, Burns JL, Campbell M, Sundar H. Hoppe RT, et al. Among authors: burns jl. J Natl Compr Canc Netw. 2022 Apr;20(4):322-334. doi: 10.6004/jnccn.2022.0021. J Natl Compr Canc Netw. 2022. PMID: 35390768
The cure rates for HL have increased so markedly with the advent of modern treatment options that overriding treatment considerations often relate to long-term toxicity. These NCCN Guidelines Insights discuss the recent updates to the NCCN Guidelines for HL focusing on (1) …
The cure rates for HL have increased so markedly with the advent of modern treatment options that overriding treatment considerations often …
NCCN Guidelines Insights: Ovarian Cancer, Version 1.2019.
Armstrong DK, Alvarez RD, Bakkum-Gamez JN, Barroilhet L, Behbakht K, Berchuck A, Berek JS, Chen LM, Cristea M, DeRosa M, ElNaggar AC, Gershenson DM, Gray HJ, Hakam A, Jain A, Johnston C, Leath CA III, Liu J, Mahdi H, Matei D, McHale M, McLean K, O'Malley DM, Penson RT, Percac-Lima S, Ratner E, Remmenga SW, Sabbatini P, Werner TL, Zsiros E, Burns JL, Engh AM. Armstrong DK, et al. Among authors: burns jl. J Natl Compr Canc Netw. 2019 Aug 1;17(8):896-909. doi: 10.6004/jnccn.2019.0039. J Natl Compr Canc Netw. 2019. PMID: 31390583
Research efforts are focused on primary neoadjuvant treatments that may improve resectability, as well as systemic therapies providing improved long-term survival. These NCCN Guidelines Insights focus on recent updates to neoadjuvant chemotherapy recommendations, including …
Research efforts are focused on primary neoadjuvant treatments that may improve resectability, as well as systemic therapies providing impro …
Hodgkin lymphoma, version 2.2015.
Hoppe RT, Advani RH, Ai WZ, Ambinder RF, Aoun P, Bello CM, Benitez CM, Bierman PJ, Blum KA, Chen R, Dabaja B, Forero A, Gordon LI, Hernandez-Ilizaliturri FJ, Hochberg EP, Huang J, Johnston PB, Khan N, Maloney DG, Mauch PM, Metzger M, Moore JO, Morgan D, Moskowitz CH, Mulroney C, Poppe M, Rabinovitch R, Seropian S, Tsien C, Winter JN, Yahalom J, Burns JL, Sundar H; National comprehensive cancer network. Hoppe RT, et al. Among authors: burns jl. J Natl Compr Canc Netw. 2015 May;13(5):554-86. doi: 10.6004/jnccn.2015.0075. J Natl Compr Canc Netw. 2015. PMID: 25964641 Free PMC article.
Brentuximab vedotin, a CD30-directed antibody-drug conjugate, has produced encouraging results in the treatment of relapsed or refractory disease. The potential long-term effects of treatment remain an important consideration, and long-term follow-up is essential af …
Brentuximab vedotin, a CD30-directed antibody-drug conjugate, has produced encouraging results in the treatment of relapsed or refractory di …
Trends in Weight Regain Following Roux-en-Y Gastric Bypass (RYGB) Bariatric Surgery.
Cooper TC, Simmons EB, Webb K, Burns JL, Kushner RF. Cooper TC, et al. Among authors: burns jl. Obes Surg. 2015 Aug;25(8):1474-81. doi: 10.1007/s11695-014-1560-z. Obes Surg. 2015. PMID: 25595383
Greater initial absolute weight loss leads to more successful long-term weight outcomes....
Greater initial absolute weight loss leads to more successful long-term weight outcomes....
Evolution of Pseudomonas aeruginosa virulence in infected patients revealed in a Dictyostelium discoideum host model.
Lelong E, Marchetti A, Simon M, Burns JL, van Delden C, Köhler T, Cosson P. Lelong E, et al. Among authors: burns jl. Clin Microbiol Infect. 2011 Sep;17(9):1415-20. doi: 10.1111/j.1469-0691.2010.03431.x. Epub 2011 Feb 3. Clin Microbiol Infect. 2011. PMID: 21091830 Free article.
However, loss of virulence is not caused predominantly by mutations in lasR. During short-term colonization of intubated patients for up to 20 days, a decrease in virulence was exceptional, despite the accumulation of lasR mutations....
However, loss of virulence is not caused predominantly by mutations in lasR. During short-term colonization of intubated patients for …
Genetic adaptation by Pseudomonas aeruginosa to the airways of cystic fibrosis patients.
Smith EE, Buckley DG, Wu Z, Saenphimmachak C, Hoffman LR, D'Argenio DA, Miller SI, Ramsey BW, Speert DP, Moskowitz SM, Burns JL, Kaul R, Olson MV. Smith EE, et al. Among authors: burns jl. Proc Natl Acad Sci U S A. 2006 May 30;103(22):8487-92. doi: 10.1073/pnas.0602138103. Epub 2006 May 10. Proc Natl Acad Sci U S A. 2006. PMID: 16687478 Free PMC article.
With the exception of intensively studied viral infections such as HIV/AIDs, little is known about the extent to which the clonal expansion that occurs during long-term infection by pathogens involves important genetic adaptations. ...
With the exception of intensively studied viral infections such as HIV/AIDs, little is known about the extent to which the clonal expansion …
Use of random amplified polymorphic DNA PCR to examine epidemiology of Stenotrophomonas maltophilia and Achromobacter (Alcaligenes) xylosoxidans from patients with cystic fibrosis.
Krzewinski JW, Nguyen CD, Foster JM, Burns JL. Krzewinski JW, et al. Among authors: burns jl. J Clin Microbiol. 2001 Oct;39(10):3597-602. doi: 10.1128/JCM.39.10.3597-3602.2001. J Clin Microbiol. 2001. PMID: 11574579 Free PMC article.
These findings suggest RAPD-PCR typing can distinguish unique CF isolates of S. maltophilia and A. xylosoxidans, person-to-person transmission may occur, there are not a small number of clones infecting CF airways, and patients with long-term colonization may either have a …
These findings suggest RAPD-PCR typing can distinguish unique CF isolates of S. maltophilia and A. xylosoxidans, person-to-person transmissi …
Calcineurin is required for skeletal muscle hypertrophy.
Dunn SE, Burns JL, Michel RN. Dunn SE, et al. Among authors: burns jl. J Biol Chem. 1999 Jul 30;274(31):21908-12. doi: 10.1074/jbc.274.31.21908. J Biol Chem. 1999. PMID: 10419511 Free article.
CsA treatment influenced the expression of muscle myofibrillar protein genes in a way reflective of fiber phenotype transformations but only in the long term of the overload condition, suggesting that the control of this growth response by calcineurin is not limited to the …
CsA treatment influenced the expression of muscle myofibrillar protein genes in a way reflective of fiber phenotype transformations but only …