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Which severe COVID-19 patients could benefit from high dose dexamethasone? A Bayesian post-hoc reanalysis of the COVIDICUS randomized clinical trial.
Chevret S, Bouadma L, Dupuis C, Burdet C, Timsit JF; COVIDICUS RCT group. Chevret S, et al. Among authors: burdet c. Ann Intensive Care. 2023 Aug 27;13(1):75. doi: 10.1186/s13613-023-01168-z. Ann Intensive Care. 2023. PMID: 37634234 Free PMC article.
TRIAL REGISTRATION: NCT04344730, date of registration April 14, 2020 ( https://clinicaltrials.gov/ct2/show/NCT04344730?term=NCT04344730&draw=2&rank=1 ); EudraCT: 2020-001457-43 ( https://www.clinicaltrialsregister.eu/ctr-search/search?...
TRIAL REGISTRATION: NCT04344730, date of registration April 14, 2020 ( https://clinicaltrials.gov/ct2/show/NCT04344730?term=NCT043447 …
A Clinical Study Provides the First Direct Evidence That Interindividual Variations in Fecal β-Lactamase Activity Affect the Gut Mycobiota Dynamics in Response to β-Lactam Antibiotics.
Delavy M, Burdet C, Sertour N, Devente S, Docquier JD, Grall N, Volant S, Ghozlane A, Duval X, Mentré F, d'Enfert C, Bougnoux ME; PrediRes Study Group. Delavy M, et al. Among authors: burdet c. mBio. 2022 Dec 20;13(6):e0288022. doi: 10.1128/mbio.02880-22. Epub 2022 Nov 30. mBio. 2022. PMID: 36448778 Free PMC article.
With a specific quantitative approach, we showed that C. albicans prevalence was much higher than previously reported, with all subjects but one being carriers of C. albicans, although with highly variable burdens. 3GCs significantly altered the mycobiota composition and the fung …
With a specific quantitative approach, we showed that C. albicans prevalence was much higher than previously reported, with all subjects but …
Association between urate-lowering therapies and cognitive decline in community-dwelling older adults.
Molet-Benhamou L, Giudici KV, de Souto Barreto P, Cantet C, Rolland Y; MAPT/DSA group. Molet-Benhamou L, et al. Sci Rep. 2022 Sep 12;12(1):15299. doi: 10.1038/s41598-022-17808-6. Sci Rep. 2022. PMID: 36097005 Free PMC article. Clinical Trial.
Long-term use of urate-lowering therapies (ULT) may reduce inflammaging and thus prevent cognitive decline during aging. This article examined the association between long-term use of ULT and cognitive decline among community-dwelling older adults with spontaneous m …
Long-term use of urate-lowering therapies (ULT) may reduce inflammaging and thus prevent cognitive decline during aging. This article …
Biological and Neuroimaging Markers as Predictors of 5-Year Incident Frailty in Older Adults: A Secondary Analysis of the MAPT Study.
Lu WH, de Souto Barreto P, Rolland Y, Bouyahia A, Fischer C, Mangin JF, Giudici KV, Vellas B; MAPT/DSA Group. Lu WH, et al. J Gerontol A Biol Sci Med Sci. 2021 Oct 13;76(11):e361-e369. doi: 10.1093/gerona/glaa296. J Gerontol A Biol Sci Med Sci. 2021. PMID: 33246338
Further longitudinal research with multiple measurements of biomarkers and frailty is needed to evaluate the long-term relationships between changes in biomarkers levels and frailty evolution....
Further longitudinal research with multiple measurements of biomarkers and frailty is needed to evaluate the long-term relationships …
Protection of the Human Gut Microbiome From Antibiotics.
de Gunzburg J, Ghozlane A, Ducher A, Le Chatelier E, Duval X, Ruppé E, Armand-Lefevre L, Sablier-Gallis F, Burdet C, Alavoine L, Chachaty E, Augustin V, Varastet M, Levenez F, Kennedy S, Pons N, Mentré F, Andremont A. de Gunzburg J, et al. Among authors: burdet c. J Infect Dis. 2018 Jan 30;217(4):628-636. doi: 10.1093/infdis/jix604. J Infect Dis. 2018. PMID: 29186529 Free PMC article. Clinical Trial.
BACKGROUND: Antibiotics are life-saving drugs but severely affect the gut microbiome with short-term consequences including diarrhea and selection of antibiotic-resistant bacteria. Long-term links to allergy and obesity are also suggested. We devised a product, DAV1 …
BACKGROUND: Antibiotics are life-saving drugs but severely affect the gut microbiome with short-term consequences including diarrhea …
Effect of long-term omega 3 polyunsaturated fatty acid supplementation with or without multidomain intervention on cognitive function in elderly adults with memory complaints (MAPT): a randomised, placebo-controlled trial.
Andrieu S, Guyonnet S, Coley N, Cantet C, Bonnefoy M, Bordes S, Bories L, Cufi MN, Dantoine T, Dartigues JF, Desclaux F, Gabelle A, Gasnier Y, Pesce A, Sudres K, Touchon J, Robert P, Rouaud O, Legrand P, Payoux P, Caubere JP, Weiner M, Carrié I, Ousset PJ, Vellas B; MAPT Study Group. Andrieu S, et al. Lancet Neurol. 2017 May;16(5):377-389. doi: 10.1016/S1474-4422(17)30040-6. Epub 2017 Mar 27. Lancet Neurol. 2017. PMID: 28359749 Clinical Trial.
Persistence of yellow fever vaccine-induced antibodies after solid organ transplantation.
Wyplosz B, Burdet C, François H, Durrbach A, Duclos-Vallée JC, Mamzer-Bruneel MF, Poujol P, Launay O, Samuel D, Vittecoq D, Consigny PH; GEVACCIM. Wyplosz B, et al. Among authors: burdet c. Am J Transplant. 2013 Sep;13(9):2458-61. doi: 10.1111/ajt.12338. Epub 2013 Jul 8. Am J Transplant. 2013. PMID: 23834702 Free article.
For the 46 patients with a known or estimated date of vaccination, yellow-fever antibodies were still detectable after a median time of 13 years (range: 2-32 years) post-immunization. Our data suggest there is long-term persistence of antibodies to yellow fever in SOT reci …
For the 46 patients with a known or estimated date of vaccination, yellow-fever antibodies were still detectable after a median time of 13 y …
How performing a repetitive one-legged stance modifies two-legged postural control.
Burdet C, Vuillerme N, Rougier PR. Burdet C, et al. J Strength Cond Res. 2011 Oct;25(10):2911-8. doi: 10.1519/JSC.0b013e31820f6ef5. J Strength Cond Res. 2011. PMID: 21912279
However, little is known about its possible increased contribution to postural control consecutive to repetitive muscular activations. To test this, the short-term effects induced by a 1-legged exercise on 2-legged postural control with the eyes closed were assessed in hea …
However, little is known about its possible increased contribution to postural control consecutive to repetitive muscular activations. To te …