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The Puerto Rican Infant Metagenomic and Epidemiologic Study of Respiratory Outcomes (PRIMERO): Design and Baseline Characteristics for a Birth Cohort Study of Early-life Viral Respiratory Illnesses and Airway Dysfunction in Puerto Rican Children.
Witonsky JI, Elhawary JR, Eng C, Oh SS, Salazar S, Contreras MG, Medina V, Secor EA, Zhang P, Everman JL, Fairbanks-Mahnke A, Pruesse E, Sajuthi SP, Chang CH, Guerrero TR, Fuentes KC, Lopez N, Montanez-Lopez CA, Otero RA, Rivera RC, Rodriguez L, Vazquez G, Hu D, Huntsman S, Jackson ND, Li Y, Morin A, Nieves NA, Rios C, Serrano G, Williams BJM, Ziv E, Moore CM, Sheppard D, Burchard EG, Seibold MA, Rodriguez Santana JR. Witonsky JI, et al. Among authors: burchard eg. medRxiv [Preprint]. 2024 Apr 16:2024.04.15.24305359. doi: 10.1101/2024.04.15.24305359. medRxiv. 2024. PMID: 38699325 Free PMC article. Preprint.
PRIMERO, the Puerto Rican Infant Metagenomics and Epidemiologic Study of Respiratory Outcomes , recruited pregnant women and their newborns to investigate how the airways develop in early life among infants exposed to different viral RIs, and will thus provide a critical understa …
PRIMERO, the Puerto Rican Infant Metagenomics and Epidemiologic Study of Respiratory Outcomes , recruited pregnant women and their newborns …
Racial/ethnic differences in eligibility for asthma biologics among pediatric populations.
Wohlford EM, Huang PF, Elhawary JR, Millette LA, Contreras MG, Witonsky J, Holweg CTJ, Oh SS, Lee C, Merenda C, Rabin RL, Araojo R, Mak ACY, Eng CS, Hu D, Huntsman S, LeNoir MA, Rodríguez-Santana JR, Borrell LN, Burchard EG. Wohlford EM, et al. Among authors: burchard eg. J Allergy Clin Immunol. 2021 Nov;148(5):1324-1331.e12. doi: 10.1016/j.jaci.2021.09.005. Epub 2021 Sep 16. J Allergy Clin Immunol. 2021. PMID: 34536416 Free PMC article.
Heterogeneity of these associations was tested using an interaction term between race/ethnicity and each exposure. Differences in therapeutic eligibility were investigated using chi-square tests. ...
Heterogeneity of these associations was tested using an interaction term between race/ethnicity and each exposure. Differences in the …
Outdoor Air Pollution and New-Onset Airway Disease. An Official American Thoracic Society Workshop Report.
Thurston GD, Balmes JR, Garcia E, Gilliland FD, Rice MB, Schikowski T, Van Winkle LS, Annesi-Maesano I, Burchard EG, Carlsten C, Harkema JR, Khreis H, Kleeberger SR, Kodavanti UP, London SJ, McConnell R, Peden DB, Pinkerton KE, Reibman J, White CW. Thurston GD, et al. Among authors: burchard eg. Ann Am Thorac Soc. 2020 Apr;17(4):387-398. doi: 10.1513/AnnalsATS.202001-046ST. Ann Am Thorac Soc. 2020. PMID: 32233861 Free PMC article.
Although it is well accepted that air pollution exposure exacerbates preexisting airway disease, it has not been firmly established that long-term pollution exposure increases the risk of new-onset asthma or chronic obstruction pulmonary disease (COPD). ...The Mechanistic …
Although it is well accepted that air pollution exposure exacerbates preexisting airway disease, it has not been firmly established that lon …
Expression of SMARCD1 interacts with age in association with asthma control on inhaled corticosteroid therapy.
McGeachie MJ, Sordillo JE, Dahlin A, Wang AL, Lutz SM, Tantisira KG, Panganiban R, Lu Q, Sajuthi S, Urbanek C, Kelly R, Saef B, Eng C, Oh SS, Kho AT, Croteau-Chonka DC, Weiss ST, Raby BA, Mak ACY, Rodriguez-Santana JR, Burchard EG, Seibold MA, Wu AC. McGeachie MJ, et al. Among authors: burchard eg. Respir Res. 2020 Jan 28;21(1):31. doi: 10.1186/s12931-020-1295-4. Respir Res. 2020. PMID: 31992292 Free PMC article.
Genomic associations were performed using regression of chronic asthma control score on gene expression with age in years as a covariate, including a multiplicative interaction term for gene expression times age. RESULTS: The SMARCD1 gene (SWI/SNF-related matrix-associated …
Genomic associations were performed using regression of chronic asthma control score on gene expression with age in years as a covariate, in …
Ancestry and genetic associations with bronchopulmonary dysplasia in preterm infants.
Torgerson DG, Ballard PL, Keller RL, Oh SS, Huntsman S, Hu D, Eng C, Burchard EG, Ballard RA; TOLSURF Study Group. Torgerson DG, et al. Among authors: burchard eg. Am J Physiol Lung Cell Mol Physiol. 2018 Nov 1;315(5):L858-L869. doi: 10.1152/ajplung.00073.2018. Epub 2018 Aug 16. Am J Physiol Lung Cell Mol Physiol. 2018. PMID: 30113228 Free PMC article. Clinical Trial.
Bronchopulmonary dysplasia in premature infants is a common and often severe lung disease with long-term sequelae. A genetic component is suspected but not fully defined. ...
Bronchopulmonary dysplasia in premature infants is a common and often severe lung disease with long-term sequelae. A genetic componen …
Apolipoprotein E epsilon 4 (APOE-ε4) genotype is associated with decreased 6-month verbal memory performance after mild traumatic brain injury.
Yue JK, Robinson CK, Burke JF, Winkler EA, Deng H, Cnossen MC, Lingsma HF, Ferguson AR, McAllister TW, Rosand J, Burchard EG, Sorani MD, Sharma S, Nielson JL, Satris GG, Talbott JF, Tarapore PE, Korley FK, Wang KKW, Yuh EL, Mukherjee P, Diaz-Arrastia R, Valadka AB, Okonkwo DO, Manley GT; TRACK‐TBI Investigators. Yue JK, et al. Among authors: burchard eg. Brain Behav. 2017 Aug 9;7(9):e00791. doi: 10.1002/brb3.791. eCollection 2017 Sep. Brain Behav. 2017. PMID: 28948085 Free PMC article.

CT pathology was the strongest predictor of decreased verbal memory (IRT: B = -8.49, SDFR: B = -2.50, SDCR: B = -1.85, LDFR: B = -2.61, LDCR: B = -2.60; p < .001). Seizure history was associated with decreased short-term memory (SDFR: B = -1.32, p = .037; SDCR: B = -1.4

…
CT pathology was the strongest predictor of decreased verbal memory (IRT: B = -8.49, SDFR: B = -2.50, SDCR: B = -1.85, LDFR: B = -2.61, LDCR …
Self-reported racial/ethnic discrimination and bronchodilator response in African American youth with asthma.
Carlson S, Borrell LN, Eng C, Nguyen M, Thyne S, LeNoir MA, Burke-Harris N, Burchard EG, Thakur N. Carlson S, et al. Among authors: burchard eg. PLoS One. 2017 Jun 13;12(6):e0179091. doi: 10.1371/journal.pone.0179091. eCollection 2017. PLoS One. 2017. PMID: 28609485 Free PMC article.
Linear regression was used to examine the association between self-reported racial/ethnic discrimination and BDR adjusted for selected characteristics. An interaction term between TNF-alpha levels and self-reported racial/ethnic discrimination was tested in the final model …
Linear regression was used to examine the association between self-reported racial/ethnic discrimination and BDR adjusted for selected chara …
Moving toward true inclusion of racial/ethnic minorities in federally funded studies. A key step for achieving respiratory health equality in the United States.
Burchard EG, Oh SS, Foreman MG, Celedón JC. Burchard EG, et al. Am J Respir Crit Care Med. 2015 Mar 1;191(5):514-21. doi: 10.1164/rccm.201410-1944PP. Am J Respir Crit Care Med. 2015. PMID: 25584658 Free PMC article.
This problem could be remedied by implementing short-, medium-, and long-term strategies, such as creating incentives to conduct minority research, ensuring fair review of grant applications focusing on minorities, developing the careers of minority scientists, and facilit …
This problem could be remedied by implementing short-, medium-, and long-term strategies, such as creating incentives to conduct mino …
Genome-wide association study of lung function phenotypes in a founder population.
Yao TC, Du G, Han L, Sun Y, Hu D, Yang JJ, Mathias R, Roth LA, Rafaels N, Thompson EE, Loisel DA, Anderson R, Eng C, Arruabarrena Orbegozo M, Young M, Klocksieben JM, Anderson E, Shanovich K, Lester LA, Williams LK, Barnes KC, Burchard EG, Nicolae DL, Abney M, Ober C. Yao TC, et al. Among authors: burchard eg. J Allergy Clin Immunol. 2014 Jan;133(1):248-55.e1-10. doi: 10.1016/j.jaci.2013.06.018. Epub 2013 Aug 6. J Allergy Clin Immunol. 2014. PMID: 23932459 Free PMC article.
BACKGROUND: Lung function is a long-term predictor of mortality and morbidity. OBJECTIVE: We sought to identify single nucleotide polymorphisms (SNPs) associated with lung function. ...
BACKGROUND: Lung function is a long-term predictor of mortality and morbidity. OBJECTIVE: We sought to identify single nucleotide pol …
Early-life air pollution and asthma risk in minority children. The GALA II and SAGE II studies.
Nishimura KK, Galanter JM, Roth LA, Oh SS, Thakur N, Nguyen EA, Thyne S, Farber HJ, Serebrisky D, Kumar R, Brigino-Buenaventura E, Davis A, LeNoir MA, Meade K, Rodriguez-Cintron W, Avila PC, Borrell LN, Bibbins-Domingo K, Rodriguez-Santana JR, Sen Ś, Lurmann F, Balmes JR, Burchard EG. Nishimura KK, et al. Among authors: burchard eg. Am J Respir Crit Care Med. 2013 Aug 1;188(3):309-18. doi: 10.1164/rccm.201302-0264OC. Am J Respir Crit Care Med. 2013. PMID: 23750510 Free PMC article.
RATIONALE: Air pollution is a known asthma trigger and has been associated with short-term asthma symptoms, airway inflammation, decreased lung function, and reduced response to asthma rescue medications. ...
RATIONALE: Air pollution is a known asthma trigger and has been associated with short-term asthma symptoms, airway inflammation, decr …