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Quantitative Magnetic Resonance Imaging of Lateral Compartment Articular Cartilage After Lateral Extra-articular Tenodesis.
Firth AD, Pritchett SL, Milner JS, Atkinson HF, Bryant DM, Holdsworth DW, Getgood AMJ. Firth AD, et al. Among authors: bryant dm. Am J Sports Med. 2024 Mar;52(4):909-918. doi: 10.1177/03635465241228193. Epub 2024 Feb 22. Am J Sports Med. 2024. PMID: 38385189
CONCLUSION: Increased relaxation times demonstrating small to medium effect sizes suggested early biochemical changes in articular cartilage of the anterolateral compartment in the ACLR + LET group compared with the ACLR alone group. Further evidence and long-term follow-u …
CONCLUSION: Increased relaxation times demonstrating small to medium effect sizes suggested early biochemical changes in articular cartilage …
Effects of Surgical Approach and Tourniquet Use on Patient-Reported Outcomes Following Total Knee Arthroplasty: A Pilot Randomized Clinical Trial.
Sogbein OA, Zomar BO, Bryant DM, Howard JL, Marsh JD, Lanting BA. Sogbein OA, et al. Among authors: bryant dm. Orthop Res Rev. 2022 Nov 15;14:407-417. doi: 10.2147/ORR.S381894. eCollection 2022. Orthop Res Rev. 2022. PMID: 36411862 Free PMC article.
As the midvastus approach does not disrupt the extensor mechanism, it may be advantageous for functional recovery, however length of stay and long-term function are similar between approaches. Tourniquet use during TKA has conflicting results in the literature. ...
As the midvastus approach does not disrupt the extensor mechanism, it may be advantageous for functional recovery, however length of stay an …
Meniscal repair at the time of primary ACLR does not negatively influence short term knee stability, graft rupture rates, or patient-reported outcome measures: the STABILITY experience.
Marmura H, Firth A, Batty L, Bryant DM, Getgood AMJ; STABILITY Study Group. Marmura H, et al. Among authors: bryant dm. Knee Surg Sports Traumatol Arthrosc. 2022 Nov;30(11):3689-3699. doi: 10.1007/s00167-022-06962-z. Epub 2022 Apr 22. Knee Surg Sports Traumatol Arthrosc. 2022. PMID: 35451638
PURPOSE: To assess how meniscal repair and excision impact short term patient-reported outcome measures (PROMs), knee stability, and early graft rupture rates following primary hamstring anterior cruciate ligament reconstruction (ACLR) with or without lateral extra-articul …
PURPOSE: To assess how meniscal repair and excision impact short term patient-reported outcome measures (PROMs), knee stability, and …
An ARF GTPase module promoting invasion and metastasis through regulating phosphoinositide metabolism.
Nacke M, Sandilands E, Nikolatou K, Román-Fernández Á, Mason S, Patel R, Lilla S, Yelland T, Galbraith LCA, Freckmann EC, McGarry L, Morton JP, Shanks E, Leung HY, Markert E, Ismail S, Zanivan S, Blyth K, Bryant DM. Nacke M, et al. Among authors: bryant dm. Nat Commun. 2021 Mar 12;12(1):1623. doi: 10.1038/s41467-021-21847-4. Nat Commun. 2021. PMID: 33712589 Free PMC article.
Induction of pro-invasive IQSEC1 variants and elevated IQSEC1 expression occurs in a number of tumour types and is associated with higher-grade metastatic cancer, activation of PI(3,4,5)P(3) signalling, and predicts long-term poor outcome across multiple cancers. IQSEC1-re …
Induction of pro-invasive IQSEC1 variants and elevated IQSEC1 expression occurs in a number of tumour types and is associated with higher-gr …
A functional genomics screen reveals a strong synergistic effect between docetaxel and the mitotic gene DLGAP5 that is mediated by the androgen receptor.
Hewit K, Sandilands E, Martinez RS, James D, Leung HY, Bryant DM, Shanks E, Markert EK. Hewit K, et al. Among authors: bryant dm. Cell Death Dis. 2018 Oct 19;9(11):1069. doi: 10.1038/s41419-018-1115-7. Cell Death Dis. 2018. PMID: 30341281 Free PMC article.
Similarly, androgen desensitized LNCaP-AI cells had a higher IC(50) to docetaxel and did not exhibit the synergistic interaction. Short-term exposure to enzalutamide did not significantly alter the behaviour of parental LNCaP cells. ...
Similarly, androgen desensitized LNCaP-AI cells had a higher IC(50) to docetaxel and did not exhibit the synergistic interaction. Short-t
Medial opening wedge high tibial osteotomy: a prospective cohort study of gait, radiographic, and patient-reported outcomes.
Birmingham TB, Giffin JR, Chesworth BM, Bryant DM, Litchfield RB, Willits K, Jenkyn TR, Fowler PJ. Birmingham TB, et al. Among authors: bryant dm. Arthritis Rheum. 2009 May 15;61(5):648-57. doi: 10.1002/art.24466. Arthritis Rheum. 2009. PMID: 19405016 Free article.
Changes in knee adduction moment observed in the first 2 years postoperatively should be explored as potential predictors of longer-term success and subgroups of patients with poor outcomes....
Changes in knee adduction moment observed in the first 2 years postoperatively should be explored as potential predictors of longer-term
Resistance training for medial compartment knee osteoarthritis and malalignment.
King LK, Birmingham TB, Kean CO, Jones IC, Bryant DM, Giffin JR. King LK, et al. Among authors: bryant dm. Med Sci Sports Exerc. 2008 Aug;40(8):1376-84. doi: 10.1249/MSS.0b013e31816f1c4a. Med Sci Sports Exerc. 2008. PMID: 18614957 Clinical Trial.
These findings provide support for future clinical trials with longer-term outcomes....
These findings provide support for future clinical trials with longer-term outcomes....