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Falsified Medicines Directive in a Secondary Care Environment-Impact on Supply Chain.
Merks P, Religioni U, Pinto de Castro N, Augustynowicz A, Plagens-Rotman K, Brindley D, Kowalczuk A, Kaźmierczak J, Neumann-Podczaska A, Blicharska E, Sola KF, Hug MJ, Gajewski K, Piątkiewicz P. Merks P, et al. Among authors: brindley d. Int J Environ Res Public Health. 2022 Mar 10;19(6):3276. doi: 10.3390/ijerph19063276. Int J Environ Res Public Health. 2022. PMID: 35328963 Free PMC article. Review.
Governments should be aware that this regulation will certainly impact public healthcare institutions in the long term....
Governments should be aware that this regulation will certainly impact public healthcare institutions in the long term....
Blockchain vehicles for efficient Medical Record management.
Vazirani AA, O'Donoghue O, Brindley D, Meinert E. Vazirani AA, et al. Among authors: brindley d. NPJ Digit Med. 2020 Jan 6;3:1. doi: 10.1038/s41746-019-0211-0. eCollection 2020. NPJ Digit Med. 2020. PMID: 31934645 Free PMC article. Review.
Furthermore, consideration must be placed on the rise of connected devices, which vastly increase the amount of data that can be collected in order to improve a patient's long-term health outcomes. Increasing numbers of healthcare systems are developing Blockchain-based sy …
Furthermore, consideration must be placed on the rise of connected devices, which vastly increase the amount of data that can be collected i …
Adipose-Derived Stem Cells in Aesthetic Surgery: A Mixed Methods Evaluation of the Current Clinical Trial, Intellectual Property, and Regulatory Landscape.
Arshad Z, Halioua-Haubold CL, Roberts M, Urso-Baiarda F, Branford OA, Brindley DA, Davies BM, Pettitt D. Arshad Z, et al. Among authors: brindley da. Aesthet Surg J. 2018 Feb 17;38(2):199-210. doi: 10.1093/asj/sjx093. Aesthet Surg J. 2018. PMID: 28591768
RESULTS: Completed clinical trials lacked robust controls, employed small sample sizes, and lacked long-term follow-up data. Ongoing clinical trials still do not address such issues. ...CONCLUSIONS: Further rigorous randomized controlled trials are required to delineate lo …
RESULTS: Completed clinical trials lacked robust controls, employed small sample sizes, and lacked long-term follow-up data. Ongoing …
Cell assisted lipotransfer in breast augmentation and reconstruction: A systematic review of safety, efficacy, use of patient reported outcomes and study quality.
Arshad Z, Karmen L, Choudhary R, Smith JA, Branford OA, Brindley DA, Pettitt D, Davies BM. Arshad Z, et al. Among authors: brindley da. JPRAS Open. 2016 Aug 24;10:5-20. doi: 10.1016/j.jpra.2016.08.004. eCollection 2016 Dec. JPRAS Open. 2016. PMID: 28066801 Free PMC article.
Presently, further technical and outcome standardization is required, in addition to rigorous randomized controlled trials and supporting long-term follow-up data to better determine procedural safety and efficacy. ...
Presently, further technical and outcome standardization is required, in addition to rigorous randomized controlled trials and supporting lo …
In vivo effects of polyunsaturated, monounsaturated, and saturated fatty acids on hepatic and peripheral insulin sensitivity.
Pereira S, Breen DM, Naassan AE, Wang PY, Uchino H, Fantus IG, Carpentier AC, Gutierrez-Juarez R, Brindley DN, Lam TK, Giacca A. Pereira S, et al. Among authors: brindley dn. Metabolism. 2015 Feb;64(2):315-22. doi: 10.1016/j.metabol.2014.10.019. Epub 2014 Oct 25. Metabolism. 2015. PMID: 25467844
Chronic ingestion of diets rich in saturated fat induces more insulin resistance than diets rich in unsaturated fat, however, it remains unclear whether different FFAs cause distinct levels of insulin resistance in the short-term, which is relevant to the feeding and fasti …
Chronic ingestion of diets rich in saturated fat induces more insulin resistance than diets rich in unsaturated fat, however, it remains unc …
Increased expression of enzymes for sphingosine 1-phosphate turnover and signaling in human decidua during late pregnancy.
Yamamoto Y, Olson DM, van Bennekom M, Brindley DN, Hemmings DG. Yamamoto Y, et al. Among authors: brindley dn. Biol Reprod. 2010 Mar;82(3):628-35. doi: 10.1095/biolreprod.109.081497. Epub 2009 Dec 9. Biol Reprod. 2010. PMID: 20007411
We found that SPHK1 protein and activity positively correlated with increasing gestational age in human decidua parietalis. This was accompanied at term by increased expression of the S1P lyase, which irreversibly degrades S1P. This implies increased S1P turnover in the de …
We found that SPHK1 protein and activity positively correlated with increasing gestational age in human decidua parietalis. This was accompa …
Cell-permeable ceramides increase basal glucose incorporation into triacylglycerols but decrease the stimulation by insulin in 3T3-L1 adipocytes.
Mei J, Wang CN, O'Brien L, Brindley DN. Mei J, et al. Among authors: brindley dn. Int J Obes Relat Metab Disord. 2003 Jan;27(1):31-9. doi: 10.1038/sj.ijo.0802183. Int J Obes Relat Metab Disord. 2003. PMID: 12532151
CONCLUSIONS: Cell-permeable ceramides can mimic some effects of TNFalpha in producing insulin resistance. However, ceramides also mediate long-term effects that enable 3T3 L1 adipocytes to take up glucose and store triacylglycerols in the absence of insulin. ...
CONCLUSIONS: Cell-permeable ceramides can mimic some effects of TNFalpha in producing insulin resistance. However, ceramides also mediate lo …
Tumor necrosis factor-alpha and ceramides in insulin resistance.
Brindley DN, Wang CN, Mei J, Xu J, Hanna AN. Brindley DN, et al. Lipids. 1999;34 Suppl:S85-8. doi: 10.1007/BF02562240. Lipids. 1999. PMID: 10419100
This effect was inhibited by blocking the activations of mitogen-activated protein kinase, phosphatidylinositol 3-kinase (PI 3-kinase), and ribosomal S6 kinase which mediated an increase in GLUT1 concentrations. Long-term increases in PI 3-kinase activity associated with i …
This effect was inhibited by blocking the activations of mitogen-activated protein kinase, phosphatidylinositol 3-kinase (PI 3-kinase), and …
Effects of cell-permeable ceramides and tumor necrosis factor-alpha on insulin signaling and glucose uptake in 3T3-L1 adipocytes.
Wang CN, O'Brien L, Brindley DN. Wang CN, et al. Among authors: brindley dn. Diabetes. 1998 Jan;47(1):24-31. doi: 10.2337/diab.47.1.24. Diabetes. 1998. PMID: 9421370
This effect was inhibited by PD 98059, LY 294002, and rapamycin, which block the activation of mitogen-activated protein kinase, phosphatidylinositol (PI) 3-kinase, and ribosomal S6 kinase, respectively. Long-term increases in PI 3-kinase activity associated with insulin r …
This effect was inhibited by PD 98059, LY 294002, and rapamycin, which block the activation of mitogen-activated protein kinase, phosphatidy …
Antiatherogenic effects of long-term benfluorex treatment in male insulin resistant JCR:LA-cp rats.
Russell JC, Graham SE, Dolphin PJ, Amy RM, Wood GO, Brindley DN. Russell JC, et al. Among authors: brindley dn. Atherosclerosis. 1997 Jul 25;132(2):187-97. doi: 10.1016/s0021-9150(97)00092-0. Atherosclerosis. 1997. PMID: 9242964
Mature, scarred myocardial lesions were essentially absent in the hearts of 39-week-old benfluorex-treated rats. Long-term major food restriction (18 g/day) decreased the body weights of obese rats to essentially those of lean control animals, with similar beneficial effec …
Mature, scarred myocardial lesions were essentially absent in the hearts of 39-week-old benfluorex-treated rats. Long-term major food …
25 results