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Unexpected cardiac arrests occurring inside the ICU: outcomes of a French prospective multicenter study.
Leloup M, Briatte I, Langlois A, Cariou A, Lesieur O; ACIR study group. Leloup M, et al. Intensive Care Med. 2020 May;46(5):1005-1015. doi: 10.1007/s00134-020-05992-w. Epub 2020 Mar 9. Intensive Care Med. 2020. PMID: 32152653
We hypothesize that certain patient characteristics and treatments are associated with survival and long-term functional outcome following in-ICU cardiac arrest. METHODS: Over a 12-month period, cardiac arrests with resuscitation attempts were prospectively investigated in …
We hypothesize that certain patient characteristics and treatments are associated with survival and long-term functional outcome foll …
Prevention of Early Ventilator-Associated Pneumonia after Cardiac Arrest.
François B, Cariou A, Clere-Jehl R, Dequin PF, Renon-Carron F, Daix T, Guitton C, Deye N, Legriel S, Plantefève G, Quenot JP, Desachy A, Kamel T, Bedon-Carte S, Diehl JL, Chudeau N, Karam E, Durand-Zaleski I, Giraudeau B, Vignon P, Le Gouge A; CRICS-TRIGGERSEP Network and the ANTHARTIC Study Group. François B, et al. N Engl J Med. 2019 Nov 7;381(19):1831-1842. doi: 10.1056/NEJMoa1812379. N Engl J Med. 2019. PMID: 31693806 Clinical Trial.
BACKGROUND: Patients who are treated with targeted temperature management after out-of-hospital cardiac arrest with shockable rhythm are at increased risk for ventilator-associated pneumonia. The benefit of preventive short-term antibiotic therapy has not been shown. METHO …
BACKGROUND: Patients who are treated with targeted temperature management after out-of-hospital cardiac arrest with shockable rhythm are at …
Effect of Human Recombinant Alkaline Phosphatase on 7-Day Creatinine Clearance in Patients With Sepsis-Associated Acute Kidney Injury: A Randomized Clinical Trial.
Pickkers P, Mehta RL, Murray PT, Joannidis M, Molitoris BA, Kellum JA, Bachler M, Hoste EAJ, Hoiting O, Krell K, Ostermann M, Rozendaal W, Valkonen M, Brealey D, Beishuizen A, Meziani F, Murugan R, de Geus H, Payen D, van den Berg E, Arend J; STOP-AKI Investigators. Pickkers P, et al. JAMA. 2018 Nov 20;320(19):1998-2009. doi: 10.1001/jama.2018.14283. JAMA. 2018. PMID: 30357272 Free PMC article. Clinical Trial.
IMPORTANCE: Sepsis-associated acute kidney injury (AKI) adversely affects long-term kidney outcomes and survival. Administration of the detoxifying enzyme alkaline phosphatase may improve kidney function and survival. ...CONCLUSIONS AND RELEVANCE: Among patients who were c …
IMPORTANCE: Sepsis-associated acute kidney injury (AKI) adversely affects long-term kidney outcomes and survival. Administration of t …
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Jakob SM, Ruokonen E, Grounds RM, Sarapohja T, Garratt C, Pocock SJ, Bratty JR, Takala J; Dexmedetomidine for Long-Term Sedation Investigators. Jakob SM, et al. JAMA. 2012 Mar 21;307(11):1151-60. doi: 10.1001/jama.2012.304. JAMA. 2012. PMID: 22436955 Clinical Trial.
CONTEXT: Long-term sedation with midazolam or propofol in intensive care units (ICUs) has serious adverse effects. ...
CONTEXT: Long-term sedation with midazolam or propofol in intensive care units (ICUs) has serious adverse effects. ...