Prolonged airway explant culture enables study of health, disease, and viral pathogenesis.
Lee-Ferris RE, Okuda K, Galiger JR, Schworer SA, Rogers TD, Dang H, Gilmore R, Edwards C, Nakano S, Cawley AM, Pickles RJ, Gallant SC, Crisci E, Rivier L, Hagood JS, O'Neal WK, Baric RS, Grubb BR, Boucher RC, Randell SH.
Lee-Ferris RE, et al. Among authors: boucher rc.
bioRxiv [Preprint]. 2024 Feb 5:2024.02.03.578756. doi: 10.1101/2024.02.03.578756.
bioRxiv. 2024.
PMID: 38370820
Free PMC article.
Preprint.
Ex vivo tissue models could overcome in vitro limitations, but methods for long-term maintenance of ex vivo tissue has not been established. We describe methods to culture human large airway explants, small airway explants, and precision-cut lung slices for at least 14 day …
Ex vivo tissue models could overcome in vitro limitations, but methods for long-term maintenance of ex vivo tissue has not been estab …