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Papillary Thyroid Microcarcinoma: Differences between Lesions in Incidental and Nonincidental Settings-Considerations on These Clinical Entities and Personal Experience.
Lucandri G, Fiori G, Falbo F, Pende V, Farina M, Mazzocchi P, Santonati A, Bosco D, Spada A, Santoro E. Lucandri G, et al. Among authors: bosco d. Curr Oncol. 2024 Feb 6;31(2):941-951. doi: 10.3390/curroncol31020070. Curr Oncol. 2024. PMID: 38392064 Free PMC article.

Other differences found in the niPTMC subgroup included a higher preoperative serum TSH level, higher hospital morbidity and a greater need for postoperative iodine ablation therapy (p < 0.05), while disease-free long-term survival did not differ between subgroups (p =

…
Other differences found in the niPTMC subgroup included a higher preoperative serum TSH level, higher hospital morbidity and a greater need …
Identification of newly synthetized proteins by mass spectrometry to understand palmitate-induced early cellular changes in pancreatic islets.
Cottet-Dumoulin D, Fonseca LM, Bignard J, Hanna R, Parnaud G, Lebreton F, Bellofatto K, Berishvili E, Berney T, Bosco D. Cottet-Dumoulin D, et al. Among authors: bosco d. Am J Physiol Endocrinol Metab. 2023 Jul 1;325(1):E21-E31. doi: 10.1152/ajpendo.00194.2022. Epub 2023 May 31. Am J Physiol Endocrinol Metab. 2023. PMID: 37257886 Free article.
These data provide information to understand the mechanisms of beta cell failure induced by lipotoxicity via the identification of all newly synthesized proteins in islets in response to short-term exposure to palmitate....
These data provide information to understand the mechanisms of beta cell failure induced by lipotoxicity via the identification of all newly …
Calcium Citrate Versus Calcium Carbonate in the Management of Chronic Hypoparathyroidism: A Randomized, Double-Blind, Crossover Clinical Trial.
Naciu AM, Tabacco G, Bilezikian JP, Santonati A, Bosco D, Incognito GG, Gaspa G, Manfrini S, Falchetti A, Trimboli P, Mazziotti G, Napoli N, Sanson G, Cesareo R, Vescini F, Palermo A. Naciu AM, et al. Among authors: bosco d. J Bone Miner Res. 2022 Jul;37(7):1251-1259. doi: 10.1002/jbmr.4564. Epub 2022 Jun 24. J Bone Miner Res. 2022. PMID: 35466449 Free PMC article. Clinical Trial.
These results are likely to have clinical implications in HypoPT, particularly those who do not tolerate CaCO(3) and those affected by nephrolithiasis. A longer-term experience is needed to confirm these findings. 2022 The Authors. ...
These results are likely to have clinical implications in HypoPT, particularly those who do not tolerate CaCO(3) and those affected by nephr …
Biosynthetic Activity Differs Between Islet Cell Types and in Beta Cells Is Modulated by Glucose and Not by Secretion.
Cottet-Dumoulin D, Lavallard V, Lebreton F, Wassmer CH, Bellofatto K, Parnaud G, Berishvili E, Berney T, Bosco D. Cottet-Dumoulin D, et al. Among authors: bosco d. Endocrinology. 2021 Mar 1;162(3):bqaa239. doi: 10.1210/endocr/bqaa239. Endocrinology. 2021. PMID: 33367617 Free PMC article.
A correct biosynthetic activity is thought to be essential for the long-term function and survival of islet cells in culture and possibly also after islet transplantation. ...
A correct biosynthetic activity is thought to be essential for the long-term function and survival of islet cells in culture and poss …
Hashimoto encephalopathy: a case report and a short revision of current literature.
Chiarello P, Talarico V, Nicoletti A, Rodio B, Arcuri PP, Bosco D, Gigliotti F, Galati MC, Raiola G. Chiarello P, et al. Among authors: bosco d. Acta Biomed. 2020 Sep 7;91(3):e2020087. doi: 10.23750/abm.v91i3.10157. Acta Biomed. 2020. PMID: 32921783 Free PMC article. Review.
Existing diagnostic criteria for adults require modification to be applied to children and adolescents, who differ from adults in their clinical presentations, clinical findings, autoantibody profiles, treatment response, and long-term outcomes. A combination of neurologic …
Existing diagnostic criteria for adults require modification to be applied to children and adolescents, who differ from adults in their clin …
Generation of insulin-secreting organoids: a step toward engineering and transplanting the bioartificial pancreas.
Wassmer CH, Lebreton F, Bellofatto K, Bosco D, Berney T, Berishvili E. Wassmer CH, et al. Among authors: bosco d. Transpl Int. 2020 Dec;33(12):1577-1588. doi: 10.1111/tri.13721. Epub 2020 Sep 27. Transpl Int. 2020. PMID: 32852858 Free PMC article. Review.
Diabetes is a major health issue of increasing prevalence. ss-cell replacement, by pancreas or islet transplantation, is the only long-term curative option for patients with insulin-dependent diabetes. ...
Diabetes is a major health issue of increasing prevalence. ss-cell replacement, by pancreas or islet transplantation, is the only long-te …
Differential response to hepatic differentiation stimuli of amniotic epithelial cells isolated from four regions of the amniotic membrane.
Passaretta F, Bosco D, Centurione L, Centurione MA, Marongiu F, Di Pietro R. Passaretta F, et al. Among authors: bosco d. J Cell Mol Med. 2020 Apr;24(7):4350-4355. doi: 10.1111/jcmm.14928. Epub 2020 Mar 6. J Cell Mol Med. 2020. PMID: 32142212 Free PMC article.
Human Amniotic Epithelial Cells (hAEC) isolated from term placenta are a promising source for regenerative medicine. However, it has long been debated whether the hAEC population consists of heterogeneous or homogeneous cells. ...The aim of this study was to evaluate the h …
Human Amniotic Epithelial Cells (hAEC) isolated from term placenta are a promising source for regenerative medicine. However, it has …
Insulin-producing organoids engineered from islet and amniotic epithelial cells to treat diabetes.
Lebreton F, Lavallard V, Bellofatto K, Bonnet R, Wassmer CH, Perez L, Kalandadze V, Follenzi A, Boulvain M, Kerr-Conte J, Goodman DJ, Bosco D, Berney T, Berishvili E. Lebreton F, et al. Among authors: bosco d. Nat Commun. 2019 Oct 3;10(1):4491. doi: 10.1038/s41467-019-12472-3. Nat Commun. 2019. PMID: 31582751 Free PMC article.
Maintaining long-term euglycemia after intraportal islet transplantation is hampered by the considerable islet loss in the peri-transplant period attributed to inflammation, ischemia and poor angiogenesis. ...
Maintaining long-term euglycemia after intraportal islet transplantation is hampered by the considerable islet loss in the peri-trans …
Islet transplantation versus insulin therapy in patients with type 1 diabetes with severe hypoglycaemia or poorly controlled glycaemia after kidney transplantation (TRIMECO): a multicentre, randomised controlled trial.
Lablanche S, Vantyghem MC, Kessler L, Wojtusciszyn A, Borot S, Thivolet C, Girerd S, Bosco D, Bosson JL, Colin C, Tetaz R, Logerot S, Kerr-Conte J, Renard E, Penfornis A, Morelon E, Buron F, Skaare K, Grguric G, Camillo-Brault C, Egelhofer H, Benomar K, Badet L, Berney T, Pattou F, Benhamou PY; TRIMECO trial investigators. Lablanche S, et al. Among authors: bosco d. Lancet Diabetes Endocrinol. 2018 Jul;6(7):527-537. doi: 10.1016/S2213-8587(18)30078-0. Epub 2018 May 15. Lancet Diabetes Endocrinol. 2018. PMID: 29776895 Clinical Trial.
INTERPRETATION: For the indications assessed in this study, islet transplantation effectively improves metabolic outcomes. Although studies with longer-term follow-up are needed, islet transplantation seems to be a valid option for patients with severe, unstable type 1 dia …
INTERPRETATION: For the indications assessed in this study, islet transplantation effectively improves metabolic outcomes. Although studies …
Targeting GLP-1 receptor trafficking to improve agonist efficacy.
Jones B, Buenaventura T, Kanda N, Chabosseau P, Owen BM, Scott R, Goldin R, Angkathunyakul N, Corrêa IR Jr, Bosco D, Johnson PR, Piemonti L, Marchetti P, Shapiro AMJ, Cochran BJ, Hanyaloglu AC, Inoue A, Tan T, Rutter GA, Tomas A, Bloom SR. Jones B, et al. Among authors: bosco d. Nat Commun. 2018 Apr 23;9(1):1602. doi: 10.1038/s41467-018-03941-2. Nat Commun. 2018. PMID: 29686402 Free PMC article.
Compared to a panel of FDA-approved GLP-1 mimetics, compounds that retain GLP-1R at the plasma membrane produce greater long-term insulin release, which is dependent on a reduction in beta-arrestin recruitment and faster agonist dissociation rates. ...
Compared to a panel of FDA-approved GLP-1 mimetics, compounds that retain GLP-1R at the plasma membrane produce greater long-term ins …
40 results