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Failure of aldosterone suppression despite angiotensin-converting enzyme (ACE) inhibitor administration in chronic heart failure is associated with ACE DD genotype.
Cicoira M, Zanolla L, Rossi A, Golia G, Franceschini L, Cabrini G, Bonizzato A, Graziani M, Anker SD, Coats AJ, Zardini P. Cicoira M, et al. Among authors: bonizzato a. J Am Coll Cardiol. 2001 Jun 1;37(7):1808-12. doi: 10.1016/s0735-1097(01)01237-2. J Am Coll Cardiol. 2001. PMID: 11401115 Free article.
METHODS: We prospectively studied 132 patients with CHF (ejection fraction <45%) receiving long-term therapy with ACE inhibitors for over six months. Patients taking aldosterone antagonists were excluded from the study. ...Angiotensin-converting enzyme gene polymorphism …
METHODS: We prospectively studied 132 patients with CHF (ejection fraction <45%) receiving long-term therapy with ACE inhibitors f …