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Relationships of change in Clinical Dementia Rating (CDR) on patient outcomes and probability of progression: observational analysis.
Tariot PN, Boada M, Lanctôt KL, Hahn-Pedersen J, Dabbous F, Udayachalerm S, Raket LL, Halchenko Y, Michalak W, Weidner W, Cummings J. Tariot PN, et al. Among authors: boada m. Alzheimers Res Ther. 2024 Feb 15;16(1):36. doi: 10.1186/s13195-024-01399-7. Alzheimers Res Ther. 2024. PMID: 38355706 Free PMC article.
BACKGROUND: Understanding the relationship among changes in Clinical Dementia Rating (CDR), patient outcomes, and probability of progression is crucial for evaluating the long-term benefits of disease-modifying treatments. We examined associations among changes in Alzheime …
BACKGROUND: Understanding the relationship among changes in Clinical Dementia Rating (CDR), patient outcomes, and probability of progression …
Awareness of Diagnosis in Persons with Early-Stage Alzheimer's Disease: An Observational Study in Spain.
Villarejo-Galende A, García-Arcelay E, Piñol-Ripoll G, Del Olmo-Rodríguez A, Viñuela F, Boada M, Franco-Macías E, de la Peña AI, Riverol M, Puig-Pijoan A, Abizanda-Soler P, Arroyo R, Baquero-Toledo M, Feria-Vilar I, Balasa M, Berbel Á, Rodríguez-Rodríguez E, Vieira-Campos A, García-Ribas G, Rodrigo-Herrero S, Lleó A, Maurino J. Villarejo-Galende A, et al. Among authors: boada m. Neurol Ther. 2022 Sep;11(3):1183-1192. doi: 10.1007/s40120-022-00367-3. Epub 2022 Jun 1. Neurol Ther. 2022. PMID: 35648383 Free PMC article.
Mean MMSE score was 24.6 (2.1) and 87.2% had a CDR-GS score of 0.5. Most participants (n = 84, 57.5%) used a descriptive term related to specific AD symptoms (e.g., memory difficulties) when asked what they called their condition. Participants aware of their diagnosis usin …
Mean MMSE score was 24.6 (2.1) and 87.2% had a CDR-GS score of 0.5. Most participants (n = 84, 57.5%) used a descriptive term related …
Neuropsychological, neuropsychiatric, and quality-of-life assessments in Alzheimer's disease patients treated with plasma exchange with albumin replacement from the randomized AMBAR study.
Boada M, López OL, Olazarán J, Núñez L, Pfeffer M, Puente O, Piñol-Ripoll G, Gámez JE, Anaya F, Kiprov D, Alegret M, Grifols C, Barceló M, Bozzo J, Szczepiorkowski ZM, Páez A; AMBAR Trial Group. Boada M, et al. Alzheimers Dement. 2022 Jul;18(7):1314-1324. doi: 10.1002/alz.12477. Epub 2021 Nov 2. Alzheimers Dement. 2022. PMID: 34726348 Free PMC article. Clinical Trial.
RESULTS: The PE-treated mild-AD cohort improved their language fluency and processing speed versus placebo at month 14 (effect sizes: >100%; P-values: .03 to .001). The moderate-AD cohort significantly improved short-term verbal memory (effect sizes: 94% to >100%; P- …
RESULTS: The PE-treated mild-AD cohort improved their language fluency and processing speed versus placebo at month 14 (effect sizes: >10 …
Monitoring HOTTIP levels on extracellular vesicles for predicting recurrence in surgical non-small cell lung cancer patients.
Han B, Marrades RM, Viñolas N, He Y, Canals J, Díaz T, Molins L, Martinez D, Moisés J, Sánchez D, Boada M, Acosta-Plasencia M, Cros-Font C, Monzo M, Navarro A. Han B, et al. Among authors: boada m. Transl Oncol. 2021 Aug;14(8):101144. doi: 10.1016/j.tranon.2021.101144. Epub 2021 Jun 7. Transl Oncol. 2021. PMID: 34111710 Free PMC article.
In resected non-small cell lung cancer (NSCLC), postsurgical recurrence is the major factor affecting long-term survival. The identification of biomarkers in extracellular vesicles (EV) obtained from serial blood samples after surgery could enhance early detection of relap …
In resected non-small cell lung cancer (NSCLC), postsurgical recurrence is the major factor affecting long-term survival. The identif …
Cognitive and Neuropsychiatric Manifestations of COVID-19 and Effects on Elderly Individuals With Dementia.
Alonso-Lana S, Marquié M, Ruiz A, Boada M. Alonso-Lana S, et al. Among authors: boada m. Front Aging Neurosci. 2020 Oct 26;12:588872. doi: 10.3389/fnagi.2020.588872. eCollection 2020. Front Aging Neurosci. 2020. PMID: 33192483 Free PMC article. Review.
In patients with dementia, COVID-19 frequently has an atypical presentation with mental status changes complicating the early identification of cases. COVID-19 has had a dramatical impact in long-term care facilities, where rates of infection and mortality have been very h …
In patients with dementia, COVID-19 frequently has an atypical presentation with mental status changes complicating the early identification …
Evaluating risk, safety and efficacy of novel reproductive techniques and therapies through the EuroGTP II risk assessment tool.
Trias E, Nijs M, Rugescu IA, Lombardo F, Nikolov G, Provoost V, Tolpe A, Vermeulen N, Veleva Z, Piteira R, Casaroli-Marano R, Tilleman K; EuroGTP II Study Group. Trias E, et al. Hum Reprod. 2020 Aug 1;35(8):1821-1838. doi: 10.1093/humrep/deaa146. Hum Reprod. 2020. PMID: 32728714
The successive steps should include testing in animal models, executing pre-clinical studies using supernumerary gametes or embryos, prospective clinical trials and finally, short- and long-term follow-up studies on the health of the offspring. A framework categorizing tre …
The successive steps should include testing in animal models, executing pre-clinical studies using supernumerary gametes or embryos, prospec …
Early Detection of Mild Cognitive Impairment (MCI) in Primary Care.
Sabbagh MN, Boada M, Borson S, Chilukuri M, Dubois B, Ingram J, Iwata A, Porsteinsson AP, Possin KL, Rabinovici GD, Vellas B, Chao S, Vergallo A, Hampel H. Sabbagh MN, et al. Among authors: boada m. J Prev Alzheimers Dis. 2020;7(3):165-170. doi: 10.14283/jpad.2020.21. J Prev Alzheimers Dis. 2020. PMID: 32463069 Review.
The rising global incidence of AD demands innovation that will help alleviate the burden to healthcare systems when coupled with the potentially near-term approval of disease-modifying therapies. Additionally, we argue that adequate infrastructure, equipment, and resources …
The rising global incidence of AD demands innovation that will help alleviate the burden to healthcare systems when coupled with the potenti …
FACEHBI: A Prospective Study of Risk Factors, Biomarkers and Cognition in a Cohort of Individuals with Subjective Cognitive Decline. Study Rationale and Research Protocols.
Rodriguez-Gomez O, Sanabria A, Perez-Cordon A, Sanchez-Ruiz D, Abdelnour C, Valero S, Hernandez I, Rosende-Roca M, Mauleon A, Vargas L, Alegret M, Espinosa A, Ortega G, Guitart M, Gailhajanet A, Sotolongo-Grau O, Moreno-Grau S, Ruiz S, Tarragona M, Serra J, Martin E, Peleja E, Lomeña F, Campos F, Vivas A, Gomez-Chiari M, Tejero MA, Giménez J, Pesini P, Sarasa M, Martinez G, Ruiz A, Tarraga L, Boada M. Rodriguez-Gomez O, et al. Among authors: boada m. J Prev Alzheimers Dis. 2017;4(2):100-108. doi: 10.14283/jpad.2016.122. J Prev Alzheimers Dis. 2017. PMID: 29186280 Clinical Trial.
BACKGROUND: Long-term longitudinal studies with multimodal biomarkers are needed to delve into the knowledge of preclinical AD. ...Mean age was 65.9 years; mean MMSE was 29.2 with a mean of 14.8 years of education. CONCLUSIONS: FACEHBI is a long-term study of cognit …
BACKGROUND: Long-term longitudinal studies with multimodal biomarkers are needed to delve into the knowledge of preclinical AD. ...Me …
Short- and Long-term Outcomes After Lung Transplantation From Circulatory-Dead Donors: A Single-Center Experience.
Ruttens D, Martens A, Ordies S, Verleden SE, Neyrinck AP, Vos R, Boada MC, Vanaudenaerde BM, Verleden GM, Van Raemdonck D. Ruttens D, et al. Among authors: boada mc. Transplantation. 2017 Nov;101(11):2691-2694. doi: 10.1097/TP.0000000000001678. Transplantation. 2017. PMID: 28207629
BACKGROUND: Donation after cardiac death (DCD) to overcome the donor organ shortage is well accepted in the clinical setting, although long-term outcome after DCD lung transplantation (LTx) remains largely unknown. METHODS: In this retrospective study, DCD LTx recipients ( …
BACKGROUND: Donation after cardiac death (DCD) to overcome the donor organ shortage is well accepted in the clinical setting, although long- …
18 results