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Cysteine string protein-alpha prevents activity-dependent degeneration in GABAergic synapses.
García-Junco-Clemente P, Cantero G, Gómez-Sánchez L, Linares-Clemente P, Martínez-López JA, Luján R, Fernández-Chacón R. García-Junco-Clemente P, et al. J Neurosci. 2010 May 26;30(21):7377-91. doi: 10.1523/JNEUROSCI.0924-10.2010. J Neurosci. 2010. PMID: 20505105 Free PMC article.
However, the mEPSC amplitude progressively decreases. Remarkably, long-term block of glutamatergic transmission in cultures lacking CSP-alpha substantially rescues Syt2-expressing GABAergic synapses from neurodegeneration. ...
However, the mEPSC amplitude progressively decreases. Remarkably, long-term block of glutamatergic transmission in cult …