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Long-Term Effectiveness and Safety of Femoropopliteal Drug-Coated Balloon Angioplasty : 5-Year Results of the Randomized Controlled EffPac Trial.
Teichgräber U, Lehmann T, Ingwersen M, Aschenbach R, Zeller T, Brechtel K, Blessing E, Lichtenberg M, von Flotow P, Heilmeier B, Sixt S, Brucks S, Erbel C, Beschorner U, Werk M, Riambau V, Wienke A, Klumb C, Thieme M, Scheinert D. Teichgräber U, et al. Among authors: blessing e. Cardiovasc Intervent Radiol. 2022 Dec;45(12):1774-1783. doi: 10.1007/s00270-022-03265-1. Epub 2022 Sep 11. Cardiovasc Intervent Radiol. 2022. PMID: 36088609 Free PMC article. Clinical Trial.
Assessment at 5 years included primary patency, freedom from clinically driven target lesion revascularization (CD-TLR), clinical improvement, and target limb amputation. Long-term vital status was ascertained in 97.1% of the participants. RESULTS: Kaplan-Meier curves at 5 …
Assessment at 5 years included primary patency, freedom from clinically driven target lesion revascularization (CD-TLR), clinical improvemen …
Orbital Atherectomy Prior to Drug-Coated Balloon Angioplasty in Calcified Infrapopliteal Lesions: A Randomized, Multicenter Pilot Study.
Zeller T, Giannopoulos S, Brodmann M, Werner M, Andrassy M, Schmidt A, Blessing E, Tepe G, Armstrong EJ. Zeller T, et al. Among authors: blessing e. J Endovasc Ther. 2022 Dec;29(6):874-884. doi: 10.1177/15266028211070968. Epub 2022 Jan 27. J Endovasc Ther. 2022. PMID: 35086385 Clinical Trial.
PURPOSE: Optimal balloon angioplasty for infrapopliteal lesions is often limited by severe calcification, which has been associated with decreased procedural success and lower long-term patency. MATERIALS AND METHODS: This was a prospective, randomized, multicenter pilot t …
PURPOSE: Optimal balloon angioplasty for infrapopliteal lesions is often limited by severe calcification, which has been associated with dec …
Impact of postoperative acute kidney injury in patients undergoing major gastrointestinal surgery on 1-year survival and renal outcomes: a national multicentre cohort study.
STARSurg Collaborative. STARSurg Collaborative. BJS Open. 2021 Nov 9;5(6):zrab134. doi: 10.1093/bjsopen/zrab134. BJS Open. 2021. PMID: 35029656 Free PMC article.
BACKGROUND: The intermediate-term impact of acute kidney injury (AKI) in patients after major gastrointestinal and liver surgery has not been well characterized. ...
BACKGROUND: The intermediate-term impact of acute kidney injury (AKI) in patients after major gastrointestinal and liver surgery has …
Stents With Torsional Strength for Superficial Femoral Artery Disease: The Prospective Q3-Registry.
Thieme M, Arjumand J, Spanagel M, Tepe G, Blessing E, Kroeg B, Reichert V, Betge S, Wickenhöfer R, Teßarek J, Ingwersen M, Krankenberg H. Thieme M, et al. Among authors: blessing e. J Endovasc Ther. 2022 Dec;29(6):904-912. doi: 10.1177/15266028211067726. Epub 2022 Jan 7. J Endovasc Ther. 2022. PMID: 34994234
CONCLUSIONS: Treatment of SFA occlusive disease in a real-world setting using the POLARIS stent with high bidirectional torsional strength is efficacious and does not raise any safety concern in the medium term. The study is registered with ClinicalTrials.gov (Identifier: …
CONCLUSIONS: Treatment of SFA occlusive disease in a real-world setting using the POLARIS stent with high bidirectional torsional strength i …
The IN.PACT DEEP Clinical Drug-Coated Balloon Trial: 5-Year Outcomes.
Zeller T, Micari A, Scheinert D, Baumgartner I, Bosiers M, Vermassen FEG, Banyai M, Shishehbor MH, Wang H, Brodmann M; IN.PACT DEEP Trial Investigators. Zeller T, et al. JACC Cardiovasc Interv. 2020 Feb 24;13(4):431-443. doi: 10.1016/j.jcin.2019.10.059. JACC Cardiovasc Interv. 2020. PMID: 32081236 Free article. Clinical Trial.
BACKGROUND: Initial studies from randomized controlled trials have shown comparable short-term outcomes of DCB angioplasty versus PTA in patients with CLI with infrapopliteal disease. However, the long-term safety and effectiveness of DCB angioplasty remain unknown …
BACKGROUND: Initial studies from randomized controlled trials have shown comparable short-term outcomes of DCB angioplasty versus PTA …
PROMISE international; a clinical post marketing trial investigating the percutaneous deep vein arterialization (LimFlow) in the treatment of no-option chronic limb ischemia patient.
Schreve MA, Lichtenberg M, Ünlü Ç, Branzan D, Schmidt A, van den Heuvel DAF, Blessing E, Brodmann M, Cabane V, Lin WTQ, Kum S. Schreve MA, et al. Among authors: blessing e. CVIR Endovasc. 2019 Jul 31;2(1):26. doi: 10.1186/s42155-019-0067-z. CVIR Endovasc. 2019. PMID: 32026120 Free PMC article.
The first results in men are promising although more research and long term follow up is needed to establish the efficacy of this new treatment modality. ...
The first results in men are promising although more research and long term follow up is needed to establish the efficacy of this new …
Clinical Trials for Opioid Use Disorder.
Blessing E, Virani S, Rotrosen J. Blessing E, et al. Handb Exp Pharmacol. 2020;258:167-202. doi: 10.1007/164_2019_304. Handb Exp Pharmacol. 2020. PMID: 31889218 Review.
., adolescents, criminal justice, pregnant women, native Americans, etc., have the potential to vastly expand treatment in the near term. Given the range of ongoing and recent trials, this chapter is not intended to be an exhaustive review but rather to present an overview …
., adolescents, criminal justice, pregnant women, native Americans, etc., have the potential to vastly expand treatment in the near term
Anticoagulation in addition to dual antiplatelet therapy has no impact on long-term follow-up after endovascular treatment of (sub)acute lower limb ischemia.
Kronlage M, Blessing E, Müller OJ, Heilmeier B, Katus HA, Erbel C. Kronlage M, et al. Among authors: blessing e. Vasa. 2019 Jul;48(4):321-329. doi: 10.1024/0301-1526/a000786. Epub 2019 Apr 8. Vasa. 2019. PMID: 30958111
Following antithrombotic regimes were compared: 1) dual antiplatelet therapy, DAPT for 4 weeks (aspirin 100 mg/d and clopidogrel 75 mg/d) upon intervention, followed by a lifelong single antiplatelet therapy; 2) DAPT plus short term anticoagulation for 4 weeks, followed by …
Following antithrombotic regimes were compared: 1) dual antiplatelet therapy, DAPT for 4 weeks (aspirin 100 mg/d and clopidogrel 75 mg/d) up …
The evidence to support the use of focal force balloon technology to improve outcomes in the treatment of lower extremity arterial occlusive disease.
Blessing E, Lugenbiel I, Holden A. Blessing E, et al. J Cardiovasc Surg (Torino). 2019 Feb;60(1):14-20. doi: 10.23736/S0021-9509.18.10766-X. Epub 2018 Oct 23. J Cardiovasc Surg (Torino). 2019. PMID: 30350932 Review.
Focal force or other specialty balloons are designed to prepare complex lesions to improve acute technical success and, ideally, long term patency of the vessel. There are numerous dedicated balloons on the market that use different modes of action to prepare the lesions. …
Focal force or other specialty balloons are designed to prepare complex lesions to improve acute technical success and, ideally, long ter
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