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Profiling the autoantibody repertoire reveals autoantibodies associated with mild cognitive impairment and dementia.
Ehtewish H, Mesleh A, Ponirakis G, Lennard K, Al Hamad H, Chandran M, Parray A, Abdesselem H, Wijten P, Decock J, Alajez NM, Ramadan M, Khan S, Ayadathil R, Own A, Elsotouhy A, Albagha O, Arredouani A, Blackburn JM, Malik RA, El-Agnaf OMA. Ehtewish H, et al. Front Neurol. 2023 Nov 30;14:1256745. doi: 10.3389/fneur.2023.1256745. eCollection 2023. Front Neurol. 2023. PMID: 38107644 Free PMC article.
Additionally, several proteins targeted by autoantibodies dysregulated in dementia were significantly enriched in the neurotrophin signaling pathway, axon guidance, cholinergic synapse, long-term potentiation, apoptosis, glycolysis and gluconeogenesis. CONCLUSION: We have …
Additionally, several proteins targeted by autoantibodies dysregulated in dementia were significantly enriched in the neurotrophin signaling …