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Establishing a consensus on wound infection definitions.
Haesler E, Swanson T, Ousey K, Larsen D, Carville K, Bjarnsholt T, Haesler P. Haesler E, et al. Among authors: bjarnsholt t. J Wound Care. 2022 Dec 1;31(Sup12):S48-S59. doi: 10.12968/jowc.2022.31.Sup12.S48. J Wound Care. 2022. PMID: 36475847
Recent guidelines/consensus documents were reviewed to identify 2-4 definitions for each term. An online consensus process was undertaken using the RAND Appropriateness Method, a consensus method for panels to reach agreement. ...The consensus process then proceeded, with …
Recent guidelines/consensus documents were reviewed to identify 2-4 definitions for each term. An online consensus process was undert …
Prophylactic treatment of breast implants with a solution of gentamicin, vancomycin and cefazolin antibiotics for women undergoing breast reconstructive surgery: protocol for a randomised, double-blind, placebo-controlled trial (The BREAST-AB trial).
Hemmingsen MN, Larsen A, Weltz TK, Ørholt M, Wiberg S, Bennedsen AK, Bille C, Carstensen LF, Jensen LT, Bredgaard R, Koudahl V, Schmidt VJ, Vester-Glowinski P, Hölmich LR, Sørensen SJ, Bjarnsholt T, Damsgaard T, Herly M. Hemmingsen MN, et al. Among authors: bjarnsholt t. BMJ Open. 2022 Sep 17;12(9):e058697. doi: 10.1136/bmjopen-2021-058697. BMJ Open. 2022. PMID: 36115667 Free PMC article.
This excludes cases where the implant is replaced with a new permanent implant, for example, for cosmetic reasons. Key long-term outcomes include capsular contracture and quality of life. The trial started on 26 January 2021 and is currently recruiting. ...
This excludes cases where the implant is replaced with a new permanent implant, for example, for cosmetic reasons. Key long-term outc …
The structure-function relationship of Pseudomonas aeruginosa in infections and its influence on the microenvironment.
Lichtenberg M, Jakobsen TH, Kühl M, Kolpen M, Jensen PØ, Bjarnsholt T. Lichtenberg M, et al. Among authors: bjarnsholt t. FEMS Microbiol Rev. 2022 Sep 2;46(5):fuac018. doi: 10.1093/femsre/fuac018. FEMS Microbiol Rev. 2022. PMID: 35472245 Free PMC article. Review.
While intensively studied, the basic mechanisms enabling the long-term survival of P. aeruginosa in the host, despite massive immune system attack and heavy antimicrobial treatment, remain to be identified. ...
While intensively studied, the basic mechanisms enabling the long-term survival of P. aeruginosa in the host, despite massive immune …
Biofilm Survival Strategies in Chronic Wounds.
Thaarup IC, Iversen AKS, Lichtenberg M, Bjarnsholt T, Jakobsen TH. Thaarup IC, et al. Among authors: bjarnsholt t. Microorganisms. 2022 Apr 5;10(4):775. doi: 10.3390/microorganisms10040775. Microorganisms. 2022. PMID: 35456825 Free PMC article. Review.
Bacterial biofilms residing in chronic wounds are thought to have numerous survival strategies, making them extremely difficult to eradicate and resulting in long-term infections. However, much of our knowledge regarding biofilm persistence stems from in vitro models and e …
Bacterial biofilms residing in chronic wounds are thought to have numerous survival strategies, making them extremely difficult to eradicate …
The zone model: A conceptual model for understanding the microenvironment of chronic wound infection.
Kirketerp-Møller K, Stewart PS, Bjarnsholt T. Kirketerp-Møller K, et al. Among authors: bjarnsholt t. Wound Repair Regen. 2020 Sep;28(5):593-599. doi: 10.1111/wrr.12841. Epub 2020 Jun 30. Wound Repair Regen. 2020. PMID: 32529778 Free PMC article.
Furthermore, we propose use of the terminology "bacterial phenotype" when describing the actions and reactions of bacteria, and the term "biofilms" to describe the morphology of the bacterial community....
Furthermore, we propose use of the terminology "bacterial phenotype" when describing the actions and reactions of bacteria, and the term …
Revival of Krebs-Ringer balanced salt solution for the investigation of polymorphonuclear leukocytes and Pseudomonas aeruginosa biofilm interaction.
Bjarnsholt T, Jensen PØ, Alhede M. Bjarnsholt T, et al. Pathog Dis. 2019 Jul 1;77(5):ftz052. doi: 10.1093/femspd/ftz052. Pathog Dis. 2019. PMID: 31529027
We show that Krebs-Ringer BSS prolonged the survival of PMNs compared to HBSS and RPMI 1640 and that the addition of 10% FBS significantly enhanced the long-term survival (20 h) compared to HS. Furthermore, we observed aggregation of Pseudomonas aeruginosa when grown in th …
We show that Krebs-Ringer BSS prolonged the survival of PMNs compared to HBSS and RPMI 1640 and that the addition of 10% FBS significantly e …
Maxillary Sinus Impaction of a Core Carrier Causing Sustained Apical Periodontitis, Sinusitis, and Nasal Stenosis: A 3-year Follow-up.
Bjørndal L, Amaloo C, Markvart M, Rud V, Qvortrup K, Stavnsbjerg C, Bjarnsholt T. Bjørndal L, et al. Among authors: bjarnsholt t. J Endod. 2016 Dec;42(12):1851-1858. doi: 10.1016/j.joen.2016.07.027. Epub 2016 Oct 18. J Endod. 2016. PMID: 27769679
Scanning electron microscopy and transmission electron microscopy showed evidence of microbial biofilm on the core carrier as well as remnants of sinus mucosa. At the long-term follow-ups, the tooth had healed apically, and symptoms of nasal stenosis were markedly reduced. …
Scanning electron microscopy and transmission electron microscopy showed evidence of microbial biofilm on the core carrier as well as remnan …
Achromobacter Species Isolated from Cystic Fibrosis Patients Reveal Distinctly Different Biofilm Morphotypes.
Nielsen SM, Nørskov-Lauritsen N, Bjarnsholt T, Meyer RL. Nielsen SM, et al. Among authors: bjarnsholt t. Microorganisms. 2016 Sep 14;4(3):33. doi: 10.3390/microorganisms4030033. Microorganisms. 2016. PMID: 27681927 Free PMC article.
The clinical significance of Achromobacter infection is not yet fully elucidated; however, their intrinsic resistance to antimicrobials and ability to form biofilms renders them capable of establishing long-term chronic infections. Still, many aspects of Achromobacter biof …
The clinical significance of Achromobacter infection is not yet fully elucidated; however, their intrinsic resistance to antimicrobials and …
The phenotypic evolution of Pseudomonas aeruginosa populations changes in the presence of subinhibitory concentrations of ciprofloxacin.
Wassermann T, Meinike Jørgensen K, Ivanyshyn K, Bjarnsholt T, Khademi SMH, Jelsbak L, Høiby N, Ciofu O. Wassermann T, et al. Among authors: bjarnsholt t. Microbiology (Reading). 2016 May;162(5):865-875. doi: 10.1099/mic.0.000273. Epub 2016 Mar 7. Microbiology (Reading). 2016. PMID: 26953154 Free article.
The immediate response of P. aeruginosa to subinhibitory concentrations of ciprofloxacin has been investigated previously. However, the long-term phenotypic adaptation, which identifies the fitted phenotypes that have been selected during evolution with subinhibitory conce …
The immediate response of P. aeruginosa to subinhibitory concentrations of ciprofloxacin has been investigated previously. However, the long …
Biofilms in wounds: a review of present knowledge.
Cooper RA, Bjarnsholt T, Alhede M. Cooper RA, et al. Among authors: bjarnsholt t. J Wound Care. 2014 Nov;23(11):570, 572-4, 576-80 passim. doi: 10.12968/jowc.2014.23.11.570. J Wound Care. 2014. PMID: 25375405 Review.
Following confirmation of the presence of biofilms in chronic wounds, the term biofilm became a buzzword within the wound healing community. ...
Following confirmation of the presence of biofilms in chronic wounds, the term biofilm became a buzzword within the wound healing com …
14 results