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COVID-19 health policy evaluation: integrating health and economic perspectives with a data envelopment analysis approach.
Klumpp M, Loske D, Bicciato S. Klumpp M, et al. Among authors: bicciato s. Eur J Health Econ. 2022 Nov;23(8):1263-1285. doi: 10.1007/s10198-021-01425-7. Epub 2022 Jan 11. Eur J Health Econ. 2022. PMID: 35015167 Free PMC article.
From an economic perspective, strategies without general lockdowns were identified as a more efficient strategy than the full lockdown strategy. Additionally, governmental support of short-term work is promising. Improving the efficiency of COVID-19 countermeasures is cruc …
From an economic perspective, strategies without general lockdowns were identified as a more efficient strategy than the full lockdown strat …
Anticancer innovative therapy congress: Highlights from the 10th anniversary edition.
De Santis F, Fucà G, Schadendorf D, Mantovani A, Magnani L, Lisanti M, Pettitt S, Bellone M, Del Sal G, Minucci S, Eggermont A, Bruzzi P, Bicciato S, Conte P, Noberini R, Hiscott J, De Braud F, Del Vecchio M, Di Nicola M. De Santis F, et al. Among authors: bicciato s. Cytokine Growth Factor Rev. 2021 Jun;59:1-8. doi: 10.1016/j.cytogfr.2021.02.001. Epub 2021 Feb 14. Cytokine Growth Factor Rev. 2021. PMID: 33610464 Review.
Overall, this conference provided scientists and clinicians with a broad overview of future challenges and hopes to improve cancer treatment reasonably in the medium-short term....
Overall, this conference provided scientists and clinicians with a broad overview of future challenges and hopes to improve cancer treatment …
Aptamers against mouse and human tumor-infiltrating myeloid cells as reagents for targeted chemotherapy.
De La Fuente A, Zilio S, Caroli J, Van Simaeys D, Mazza EMC, Ince TA, Bronte V, Bicciato S, Weed DT, Serafini P. De La Fuente A, et al. Among authors: bicciato s. Sci Transl Med. 2020 Jun 17;12(548):eaav9760. doi: 10.1126/scitranslmed.aav9760. Sci Transl Med. 2020. PMID: 32554710 Free PMC article.
Local delivery of anticancer agents has the potential to maximize treatment efficacy and minimize the acute and long-term systemic toxicities. Here, we used unsupervised systematic evolution of ligands by exponential enrichment to identify four RNA aptamers that specifical …
Local delivery of anticancer agents has the potential to maximize treatment efficacy and minimize the acute and long-term systemic to …
The tissue inhibitor of metalloproteinases 1 increases the clonogenic efficiency of human hematopoietic progenitor cells through CD63/PI3K/Akt signaling.
Rossi L, Forte D, Migliardi G, Salvestrini V, Buzzi M, Ricciardi MR, Licchetta R, Tafuri A, Bicciato S, Cavo M, Catani L, Lemoli RM, Curti A. Rossi L, et al. Among authors: bicciato s. Exp Hematol. 2015 Nov;43(11):974-985.e1. doi: 10.1016/j.exphem.2015.07.003. Epub 2015 Jul 23. Exp Hematol. 2015. PMID: 26213230 Free article.
We found that rhTIMP-1 affects in vitro cell survival, proliferation, and particularly clonogenic expansion of CD34(+) HSPCs without compromising their short-term engraftment potential after transplantation into immunodeficient mice. ...
We found that rhTIMP-1 affects in vitro cell survival, proliferation, and particularly clonogenic expansion of CD34(+) HSPCs without comprom …
Aryl hydrocarbon receptor control of a disease tolerance defence pathway.
Bessede A, Gargaro M, Pallotta MT, Matino D, Servillo G, Brunacci C, Bicciato S, Mazza EM, Macchiarulo A, Vacca C, Iannitti R, Tissi L, Volpi C, Belladonna ML, Orabona C, Bianchi R, Lanz TV, Platten M, Della Fazia MA, Piobbico D, Zelante T, Funakoshi H, Nakamura T, Gilot D, Denison MS, Guillemin GJ, DuHadaway JB, Prendergast GC, Metz R, Geffard M, Boon L, Pirro M, Iorio A, Veyret B, Romani L, Grohmann U, Fallarino F, Puccetti P. Bessede A, et al. Among authors: bicciato s. Nature. 2014 Jul 10;511(7508):184-90. doi: 10.1038/nature13323. Nature. 2014. PMID: 24930766 Free PMC article.
We found that a first exposure of mice to LPS activated the ligand-operated transcription factor aryl hydrocarbon receptor (AhR) and the hepatic enzyme tryptophan 2,3-dioxygenase, which provided an activating ligand to the former, to downregulate early inflammatory gene expressio …
We found that a first exposure of mice to LPS activated the ligand-operated transcription factor aryl hydrocarbon receptor (AhR) and the hep …
Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells.
Pallotta MT, Orabona C, Volpi C, Vacca C, Belladonna ML, Bianchi R, Servillo G, Brunacci C, Calvitti M, Bicciato S, Mazza EM, Boon L, Grassi F, Fioretti MC, Fallarino F, Puccetti P, Grohmann U. Pallotta MT, et al. Among authors: bicciato s. Nat Immunol. 2011 Jul 31;12(9):870-8. doi: 10.1038/ni.2077. Nat Immunol. 2011. PMID: 21804557
In inflammation, interferon-gamma is the main inducer of IDO for the prevention of hyperinflammatory responses, yet IDO is also responsible for self-tolerance effects in the longer term. Here we show that treatment of mouse plasmacytoid DCs (pDCs) with transforming growth …
In inflammation, interferon-gamma is the main inducer of IDO for the prevention of hyperinflammatory responses, yet IDO is also responsible …
Tumor-induced tolerance and immune suppression depend on the C/EBPbeta transcription factor.
Marigo I, Bosio E, Solito S, Mesa C, Fernandez A, Dolcetti L, Ugel S, Sonda N, Bicciato S, Falisi E, Calabrese F, Basso G, Zanovello P, Cozzi E, Mandruzzato S, Bronte V. Marigo I, et al. Among authors: bicciato s. Immunity. 2010 Jun 25;32(6):790-802. doi: 10.1016/j.immuni.2010.05.010. Epub 2010 Jun 3. Immunity. 2010. PMID: 20605485 Free article.
BM-MDSCs induced by GM-CSF+IL-6 possessed the highest tolerogenic activity, as revealed by the ability to impair the priming of CD8(+) T cells and allow long term acceptance of pancreatic islet allografts. Cytokines inducing MDSCs acted on a common molecular pathway and th …
BM-MDSCs induced by GM-CSF+IL-6 possessed the highest tolerogenic activity, as revealed by the ability to impair the priming of CD8(+) T cel …
Microarray data mining using Bioconductor packages.
Nie H, Neerincx PB, van der Poel J, Ferrari F, Bicciato S, Leunissen JA, Groenen MA. Nie H, et al. Among authors: bicciato s. BMC Proc. 2009 Jul 16;3 Suppl 4(Suppl 4):S9. doi: 10.1186/1753-6561-3-S4-S9. BMC Proc. 2009. PMID: 19615122 Free PMC article.
BACKGROUND: This paper describes the results of a Gene Ontology (GO) term enrichment analysis of chicken microarray data using the Bioconductor packages. ...
BACKGROUND: This paper describes the results of a Gene Ontology (GO) term enrichment analysis of chicken microarray data using the Bi …