Functional diversification and dynamics of CAR-T cells in patients with B-ALL.
Li Z, Zhao L, Zhang Y, Zhu L, Mu W, Ge T, Jin J, Tan J, Cheng J, Wang J, Wang N, Zhou X, Chen L, Chang Z, Liu C, Bian Z, Liu B, Ye L, Lan Y, Huang L, Zhou J.
Li Z, et al. Among authors: bian z.
Cell Rep. 2023 Oct 31;42(10):113263. doi: 10.1016/j.celrep.2023.113263. Epub 2023 Oct 17.
Cell Rep. 2023.
PMID: 37851569
Free article.
We molecularly identify eight CAR-T cell subtypes, including three cytotoxic subtypes with distinct kinetics and three dual-identity subtypes with non-T cell characteristics. Remarkably, long-term remission is coincident with the dominance of cytotoxic subtypes, while leuk …
We molecularly identify eight CAR-T cell subtypes, including three cytotoxic subtypes with distinct kinetics and three dual-identity subtype …