Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

12 results

Filters applied: . Clear all
Page 1
Intestinal IL-22RA1 signaling regulates intrinsic and systemic lipid and glucose metabolism to alleviate obesity-associated disorders.
Gaudino SJ, Singh A, Huang H, Padiadpu J, Jean-Pierre M, Kempen C, Bahadur T, Shiomitsu K, Blumberg R, Shroyer KR, Beyaz S, Shulzhenko N, Morgun A, Kumar P. Gaudino SJ, et al. Among authors: beyaz s. Nat Commun. 2024 Feb 21;15(1):1597. doi: 10.1038/s41467-024-45568-6. Nat Commun. 2024. PMID: 38383607 Free PMC article.
Here we examine the importance of tissue-specific IL-22RA1 signaling in mediating long-term high fat diet (HFD) driven metabolic disorders. To do so, we generated intestinal epithelium-, liver-, and white adipose tissue (WAT)-specific Il22ra1 knockout and littermate contro …
Here we examine the importance of tissue-specific IL-22RA1 signaling in mediating long-term high fat diet (HFD) driven metabolic diso …
p17/C18-ceramide-mediated mitophagy is an endogenous neuroprotective response in preclinical and clinical brain injury.
Karakaya E, Oleinik N, Edwards J, Tomberlin J, Barker RB, Berber B, Ericsson M, Alsudani H, Ergul A, Beyaz S, Lemasters JJ, Ogretmen B, Albayram O. Karakaya E, et al. Among authors: beyaz s. PNAS Nexus. 2024 Feb 7;3(2):pgae018. doi: 10.1093/pnasnexus/pgae018. eCollection 2024 Feb. PNAS Nexus. 2024. PMID: 38328780 Free PMC article.
Repeat concussions (or repetitive mild traumatic brain injury [rmTBI]) are complex pathological processes consisting of a primary insult and long-term secondary complications and are also a prerequisite for chronic traumatic encephalopathy (CTE). ...Using a novel repetitiv …
Repeat concussions (or repetitive mild traumatic brain injury [rmTBI]) are complex pathological processes consisting of a primary insult and …
Excess Dietary Sugar Alters Colonocyte Metabolism and Impairs the Proliferative Response to Damage.
Burr AHP, Ji J, Ozler K, Mentrup HL, Eskiocak O, Yueh B, Cumberland R, Menk AV, Rittenhouse N, Marshall CW, Chiaranunt P, Zhang X, Mullinax L, Overacre-Delgoffe A, Cooper VS, Poholek AC, Delgoffe GM, Mollen KP, Beyaz S, Hand TW. Burr AHP, et al. Among authors: beyaz s. Cell Mol Gastroenterol Hepatol. 2023;16(2):287-316. doi: 10.1016/j.jcmgh.2023.05.001. Epub 2023 May 11. Cell Mol Gastroenterol Hepatol. 2023. PMID: 37172822 Free PMC article.
CONCLUSIONS: Taken together, our results indicate that short-term, excess dietary sucrose can directly modulate intestinal crypt cell metabolism and inhibit ISC/TA cell regenerative proliferation. ...
CONCLUSIONS: Taken together, our results indicate that short-term, excess dietary sucrose can directly modulate intestinal crypt cell …
Establishing patient-derived organoids from human endometrial cancer and normal endometrium.
Katcher A, Yueh B, Ozler K, Nizam A, Kredentser A, Chung C, Frimer M, Goldberg GL, Beyaz S. Katcher A, et al. Among authors: beyaz s. Front Endocrinol (Lausanne). 2023 Apr 14;14:1059228. doi: 10.3389/fendo.2023.1059228. eCollection 2023. Front Endocrinol (Lausanne). 2023. PMID: 37124727 Free PMC article.
Organoids were created from all major endometrial cancer histologic subtypes. These organoids are passaged long term, banked and can be utilized for downstream histological and genomic characterization as well as functional assays such as assessing the response to therapeu …
Organoids were created from all major endometrial cancer histologic subtypes. These organoids are passaged long term, banked and can …
Neurotensin neurons in the extended amygdala control dietary choice and energy homeostasis.
Furlan A, Corona A, Boyle S, Sharma R, Rubino R, Habel J, Gablenz EC, Giovanniello J, Beyaz S, Janowitz T, Shea SD, Li B. Furlan A, et al. Among authors: beyaz s. Nat Neurosci. 2022 Nov;25(11):1470-1480. doi: 10.1038/s41593-022-01178-3. Epub 2022 Oct 20. Nat Neurosci. 2022. PMID: 36266470 Free PMC article.
Chronic inactivation of IPAC(Nts) neurons recapitulates these effects, reduces preference for sweet, non-caloric tastants and, furthermore, enhances locomotion and energy expenditure; as a result, mice display long-term weight loss and improved metabolic health and are pro …
Chronic inactivation of IPAC(Nts) neurons recapitulates these effects, reduces preference for sweet, non-caloric tastants and, furthermore, …
A brief history of artificial intelligence and robotic surgery in orthopedics & traumatology and future expectations.
Beyaz S. Beyaz S. Jt Dis Relat Surg. 2020;31(3):653-655. doi: 10.5606/ehc.2020.75300. Jt Dis Relat Surg. 2020. PMID: 32962606 Free PMC article. Review.
Although studies indicate that new technologies are more successful than humans, the replacement of technology with experience and long-term results with traditional methods will not be observed in the near future....
Although studies indicate that new technologies are more successful than humans, the replacement of technology with experience and long-t …
Femoral neck fracture detection in X-ray images using deep learning and genetic algorithm approaches.
Beyaz S, Açıcı K, Sümer E. Beyaz S, et al. Jt Dis Relat Surg. 2020;31(2):175-183. doi: 10.5606/ehc.2020.72163. Epub 2020 Mar 26. Jt Dis Relat Surg. 2020. PMID: 32584712 Free PMC article.
Learning rate was dropped by a factor of 0.5 on every five epochs. To reduce overfitting, regularization term was added to the weights of the loss function. The training process was repeated for pixel sizes 50x50, 100x100, 200x200, and 400x400. ...
Learning rate was dropped by a factor of 0.5 on every five epochs. To reduce overfitting, regularization term was added to the weight …
Distribution and storage of inflammatory memory in barrier tissues.
Ordovas-Montanes J, Beyaz S, Rakoff-Nahoum S, Shalek AK. Ordovas-Montanes J, et al. Among authors: beyaz s. Nat Rev Immunol. 2020 May;20(5):308-320. doi: 10.1038/s41577-019-0263-z. Epub 2020 Feb 3. Nat Rev Immunol. 2020. PMID: 32015472 Free PMC article. Review.
To effectively inform future responses, these past experiences can be stored in cell types that are long-term residents or essential constituents of tissues. There is an emerging understanding that, in addition to antigen-specific immune cells, diverse haematopoietic, stro …
To effectively inform future responses, these past experiences can be stored in cell types that are long-term residents or essential …
Six-Month Results of Cervical Intradiscal Oxygen-Ozone Mixture Therapy on Patients with Neck Pain: Preliminary Findings.
Beyaz SG, Sayhan H. Beyaz SG, et al. Pain Physician. 2018 Jul;21(4):E449-E456. Pain Physician. 2018. PMID: 30045611 Free article.
CONCLUSION: Based on our results, intradiscal injection of an O2-O3 mixture treatment showed a beneficial long-term effect. KEY WORDS: Cervical disc herniation, chemonucleolysis, injection, intradiscal, oxygen-ozone mixture, percutaneous treatment....
CONCLUSION: Based on our results, intradiscal injection of an O2-O3 mixture treatment showed a beneficial long-term effect. KEY WORDS …
Long-term Clinical Effects of DiscoGel for Cervical Disc Herniation.
Sayhan H, Beyaz SG, Ülgen AM, Yuce MF, Tomak Y. Sayhan H, et al. Among authors: beyaz sg. Pain Physician. 2018 Jan;21(1):E71-E78. Pain Physician. 2018. PMID: 29357343 Free article.
It has also been used in cervical disc herniations (CDHs), demonstrating the potential efficacy of this substance. OBJECTIVE: The aim of the study is to investigate the long-term effectiveness and safety of DiscoGel in patients with CDH and chronic neck pain. ...LIMITATION …
It has also been used in cervical disc herniations (CDHs), demonstrating the potential efficacy of this substance. OBJECTIVE: The aim of the …
12 results