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Involvement of CFTR in the pathogenesis of pulmonary arterial hypertension.
Eur Respir J. 2021 Nov 25;58(5):2000653. doi: 10.1183/13993003.00653-2020. Print 2021 Nov.
Eur Respir J. 2021.
PMID: 33926975
Free article.
CFTR-mediated pulmonary artery relaxation was reduced in pulmonary arteries from iPAH patients and rats with monocrotaline- or chronic hypoxia-induced PH. Long-term in vivo CFTR inhibition in rats significantly increased right ventricular systolic pressure, which was relat …
CFTR-mediated pulmonary artery relaxation was reduced in pulmonary arteries from iPAH patients and rats with monocrotaline- or chronic hypox …
Short-term consequences of F508del-CFTR thermal instability on CFTR-dependent transepithelial currents in human airway epithelial cells.
Froux L, Coraux C, Sage E, Becq F.
Froux L, et al. Among authors: becq f.
Sci Rep. 2019 Sep 24;9(1):13729. doi: 10.1038/s41598-019-50066-7.
Sci Rep. 2019.
PMID: 31551433
Free PMC article.
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Chronic exposure to EGF affects trafficking and function of ENaC channel in cystic fibrosis cells.
Cao L, Owsianik G, Becq F, Nilius B.
Cao L, et al. Among authors: becq f.
Biochem Biophys Res Commun. 2005 Jun 3;331(2):503-11. doi: 10.1016/j.bbrc.2005.03.201.
Biochem Biophys Res Commun. 2005.
PMID: 15850788
Western-blot analysis showed that in standard medium cells expressed fast-migrating EndoH-insensitive and slow-migrating EndoH-sensitive alphaENaC fractions, while in cells growing in the presence of EGF, alphaENaC was only detected as the fast-migrating EndoH-insensitive fractio …
Western-blot analysis showed that in standard medium cells expressed fast-migrating EndoH-insensitive and slow-migrating EndoH-sensitive alp …
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