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Mechanistic model of radiotherapy-induced lung fibrosis using coupled 3D agent-based and Monte Carlo simulations.
Cogno N, Bauer R, Durante M. Cogno N, et al. Among authors: bauer r. Commun Med (Lond). 2024 Feb 9;4(1):16. doi: 10.1038/s43856-024-00442-w. Commun Med (Lond). 2024. PMID: 38336802 Free PMC article.
Among the various approaches, agent-based models are appealing as they provide the means to include patient-specific parameters and simulate long-term effects in complex systems. However, Monte Carlo tools remain the state-of-the-art for modelling radiation transport and p …
Among the various approaches, agent-based models are appealing as they provide the means to include patient-specific parameters and simulate …
Evaluation of the Rotational Stability of Directional Deep Brain Stimulation Leads: A Case Series and Systematic Review.
Cavalloni F, Brugger F, Kägi G, Naseri Y, Brogle D, Bozinov O, Bauer R, Hägele-Link S, Krüger MT. Cavalloni F, et al. Among authors: bauer r. J Neurol Surg A Cent Eur Neurosurg. 2024 May;85(3):288-293. doi: 10.1055/s-0043-1775759. Epub 2023 Oct 13. J Neurol Surg A Cent Eur Neurosurg. 2024. PMID: 37832590
Data on directional lead stability are limited and controversial. METHODS: We aimed to evaluate the long-term rotational stability of directional leads and define confounding factors in our own population and the current literature. ...CONCLUSION: Directional leads for dee …
Data on directional lead stability are limited and controversial. METHODS: We aimed to evaluate the long-term rotational stability of …
Longitudinal Digital Mood Charting in Bipolar Disorder: Experiences with ChronoRecord Over 20 Years.
Bauer M, Glenn T, Alda M, Grof P, Bauer R, Ebner-Priemer UW, Ehrlich S, Pfennig A, Pilhatsch M, Rasgon N, Whybrow PC. Bauer M, et al. Among authors: bauer r. Pharmacopsychiatry. 2023 Sep;56(5):182-187. doi: 10.1055/a-2156-5667. Epub 2023 Sep 7. Pharmacopsychiatry. 2023. PMID: 37678394 Free PMC article.
INTRODUCTION: Longitudinal study is an essential methodology for understanding disease trajectories, treatment effects, symptom changes, and long-term outcomes of affective disorders. Daily self-charting of mood and other illness-related variables is a commonly recommended …
INTRODUCTION: Longitudinal study is an essential methodology for understanding disease trajectories, treatment effects, symptom changes, and …
Possible role of the gut microbiome in mediating the beneficial effects of the six-herbal formulation STW 5-II on digestive health.
Ammar RM, Pferschy-Wenzig EM, Van den Abbeele P, Verstrepen L, Ghyselinck J, Thumann T, Bauer R. Ammar RM, et al. Among authors: bauer r. Phytomedicine. 2023 Oct;119:154996. doi: 10.1016/j.phymed.2023.154996. Epub 2023 Aug 4. Phytomedicine. 2023. PMID: 37595389 Free article.
METHODS: STW 5-II was incubated with human fecal microbiota in a short-term colonic model. In the samples, the impact of STW 5-II on microbial fermentation capacity (pH, gas production), short chain fatty acid (SCFA) production, and microbial composition (Illumina 16S rRNA …
METHODS: STW 5-II was incubated with human fecal microbiota in a short-term colonic model. In the samples, the impact of STW 5-II on …
Individualized network analysis: A novel approach to investigate tau PET using graph theory in the Alzheimer's disease continuum.
Protas H, Ghisays V, Goradia DD, Bauer R 3rd, Devadas V, Chen K, Reiman EM, Su Y. Protas H, et al. Among authors: bauer r 3rd. Front Neurosci. 2023 Mar 2;17:1089134. doi: 10.3389/fnins.2023.1089134. eCollection 2023. Front Neurosci. 2023. PMID: 36937677 Free PMC article.
We also investigate the correlation of these network and regional measures and a measure of memory performance, auditory verbal learning test for long-term recall memory (AVLT-LTM). Finally, we determine the stages based on global efficiency and limbic strength using condi …
We also investigate the correlation of these network and regional measures and a measure of memory performance, auditory verbal learning tes …
Functional RNA Dynamics Are Progressively Governed by RNA Destabilization during the Adaptation to Chronic Hypoxia.
Bauer R, Meyer SP, Kloss KA, Guerrero Ruiz VM, Reuscher S, Zhou Y, Fuhrmann DC, Zarnack K, Schmid T, Brüne B. Bauer R, et al. Int J Mol Sci. 2022 May 22;23(10):5824. doi: 10.3390/ijms23105824. Int J Mol Sci. 2022. PMID: 35628634 Free PMC article. Review.
While total mRNA changes correlated well with enhanced transcription during short-term hypoxia, mRNA destabilization gained importance under chronic conditions. ...
While total mRNA changes correlated well with enhanced transcription during short-term hypoxia, mRNA destabilization gained importanc …
Tocilizumab in patients hospitalised with COVID-19 pneumonia: Efficacy, safety, viral clearance, and antibody response from a randomised controlled trial (COVACTA).
Rosas IO, Bräu N, Waters M, Go RC, Malhotra A, Hunter BD, Bhagani S, Skiest D, Savic S, Douglas IS, Garcia-Diaz J, Aziz MS, Cooper N, Youngstein T, Sorbo LD, Zerda DJ, Ustianowski A, Gracian AC, Blyth KG, Carratalà J, François B, Benfield T, Haslem D, Bonfanti P, van der Leest CH, Rohatgi N, Wiese L, Luyt CE, Bauer RN, Cai F, Lee IT, Matharu B, Metcalf L, Wildum S, Graham E, Tsai L, Bao M. Rosas IO, et al. Among authors: bauer rn. EClinicalMedicine. 2022 May;47:101409. doi: 10.1016/j.eclinm.2022.101409. Epub 2022 Apr 21. EClinicalMedicine. 2022. PMID: 35475258 Free PMC article.
BACKGROUND: In COVACTA, a randomised, placebo-controlled trial in patients hospitalised with coronavirus disease-19 (COVID-19), tocilizumab did not improve 28-day mortality, but shortened hospital and intensive care unit stay. Longer-term effects of tocilizumab in patients …
BACKGROUND: In COVACTA, a randomised, placebo-controlled trial in patients hospitalised with coronavirus disease-19 (COVID-19), tocilizumab …
Predicting Clinical Outcomes 7-10 Years after Severe Traumatic Brain Injury: Exploring the Prognostic Utility of the IMPACT Lab Model and Cerebrospinal Fluid UCH-L1 and MAP-2.
Svingos AM, Robicsek SA, Hayes RL, Wang KK, Robertson CS, Brophy GM, Papa L, Gabrielli A, Hannay HJ, Bauer RM, Heaton SC. Svingos AM, et al. Among authors: bauer rm. Neurocrit Care. 2022 Aug;37(1):172-183. doi: 10.1007/s12028-022-01461-y. Epub 2022 Mar 1. Neurocrit Care. 2022. PMID: 35229233
METHODS: Very long-term global outcome was assessed in a total of 59 participants (41 of whom did not survive their injuries) using the Glasgow Outcome Scale-Extended and Disability Rating Scale. ...Higher IMPACT lab model risk scores predicted greater extent of very long- …
METHODS: Very long-term global outcome was assessed in a total of 59 participants (41 of whom did not survive their injuries) using t …
Age at surgery is not a prognostic factor for the AdVance-XP male sling efficacy: A post-hoc analysis of a prospective 7-year multicentric study.
Mumm JN, Abrarova B, Schütz J, Klehr B, Rodler S, Vilsmaier T, Gozzi C, Rehder P, May F, Homberg R, Gebhartl P, Stief CG, Buchner A, Bauer RM. Mumm JN, et al. Among authors: bauer rm. Neurourol Urodyn. 2021 Aug;40(6):1616-1624. doi: 10.1002/nau.24727. Epub 2021 Jun 3. Neurourol Urodyn. 2021. PMID: 34082470
OBJECTIVE: To evaluate the factor age at the surgery on long-term postoperative outcomes in patients with postprostatectomy incontinence (PPI) after AdVance XP transobturator male sling implantation. ...
OBJECTIVE: To evaluate the factor age at the surgery on long-term postoperative outcomes in patients with postprostatectomy incontine …
The Role of the Pathogen Dose and PI3Kγ in Immunometabolic Reprogramming of Microglia for Innate Immune Memory.
Lajqi T, Marx C, Hudalla H, Haas F, Große S, Wang ZQ, Heller R, Bauer M, Wetzker R, Bauer R. Lajqi T, et al. Among authors: bauer r. Int J Mol Sci. 2021 Mar 4;22(5):2578. doi: 10.3390/ijms22052578. Int J Mol Sci. 2021. PMID: 33806610 Free PMC article.
Microglia, the innate immune cells of the CNS, exhibit long-term response changes indicative of innate immune memory (IIM). Our previous studies revealed IIM patterns of microglia with opposing immune phenotypes: trained immunity after a low dose and immune tolerance after …
Microglia, the innate immune cells of the CNS, exhibit long-term response changes indicative of innate immune memory (IIM). Our previ …
127 results