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CAR T-cell therapy induces a high rate of prolonged remission in relapsed primary CNS lymphoma: Real-life results of the LOC network.
Choquet S, Soussain C, Azar N, Morel V, Metz C, Ursu R, Waultier-Rascalou A, di Blasi R, Houot R, Souchet L, Roos-Weil D, Uzunov M, Quoc SN, Jacque N, Boussen I, Gauthier N, Ouzegdouh M, Blonski M, Campidelli A, Ahle G, Guffroy B, Willems L, Corvilain E, Barrie M, Alcantara M, le Garff-Tavernier M, Psimaras D, Weiss N, Baron M, Bravetti C, Hoang-Xuan K, Davi F, Shor N, Alentorn A, Houillier C. Choquet S, et al. Among authors: baron m. Am J Hematol. 2024 Apr 8. doi: 10.1002/ajh.27316. Online ahead of print. Am J Hematol. 2024. PMID: 38586986
CAR T-cells are effective in relapsed PCNSL, with a high rate of long-term remission and a reassuring tolerance profile. The results seem clearly superior to those usually observed in this setting....
CAR T-cells are effective in relapsed PCNSL, with a high rate of long-term remission and a reassuring tolerance profile. The results …
Proton pump inhibitors in systemic sclerosis: a reappraisal to optimise treatment of gastro-oesophageal reflux disease.
Hughes M, Allanore Y, Baron M, Del Galdo F, Denton CP, Frech T, Furst DE, Galetti I, Dagna L, Herrick AL, Kuwana M, Matucci-Cerinic P, McMahan ZH, Murray CD, Proudman S, Matucci-Cerinic M. Hughes M, et al. Among authors: baron m. Lancet Rheumatol. 2022 Nov;4(11):e795-e803. doi: 10.1016/S2665-9913(22)00183-7. Epub 2022 Jul 25. Lancet Rheumatol. 2022. PMID: 37936680 Free PMC article.
However, currently there is little evidence currently to support the empiric use of PPIs in SSc which is especially relevant in regard to safety concerns of long-term exposure with have been raised in the general population. The purpose of this viewpoint is to highlight th …
However, currently there is little evidence currently to support the empiric use of PPIs in SSc which is especially relevant in regard to sa …
Intravesical injections of botulinum neurotoxin A to treat overactive bladder and/or detrusor overactivity related to multiple sclerosis: 5-Year continuation rate and specific risk factors for discontinuation-A study from the neuro-urology committee of the French Association of Urology.
Delaval S, Dequirez PL, Hentzen C, Baron M, Mille E, Tariel F, Peyronnet B, Perrouin-Verbe MA, Pierache A, Chartier-Kastler E, Capon G, Cornu JN, Castel-Lacanal E, Gamé X, Karsenty G, Ruffion A, Denys P, Even A, Joussain C, Amarenco G, Phé V, Biardeau X. Delaval S, et al. Among authors: baron m. Mult Scler. 2023 Jul;29(8):1024-1032. doi: 10.1177/13524585231174580. Epub 2023 Jun 2. Mult Scler. 2023. PMID: 37264947
BACKGROUND: While intravesical injections of botulinum neurotoxin A (BoNT-A) are currently recommended for patients experiencing refractory neurogenic overactive bladder and/or detrusor overactivity (OAB/DO), it is unclear how much this therapy is effective and sustainable in the …
BACKGROUND: While intravesical injections of botulinum neurotoxin A (BoNT-A) are currently recommended for patients experiencing refractory …
Effect of pregnancy on scleroderma progression.
Deshauer S, Junek M, Baron M, Beattie KA, Larché MJ. Deshauer S, et al. Among authors: baron m. J Scleroderma Relat Disord. 2023 Feb;8(1):27-30. doi: 10.1177/23971983221101311. Epub 2022 Jun 19. J Scleroderma Relat Disord. 2023. PMID: 36743807 Free PMC article.
CONCLUSION: Results demonstrated that having 1 pregnancy after systemic sclerosis diagnosis did not appear to significantly impact long-term renal, respiratory, or global function outcomes. While this offers a hopeful message to systemic sclerosis patients planning a pregn …
CONCLUSION: Results demonstrated that having 1 pregnancy after systemic sclerosis diagnosis did not appear to significantly impact long-t …
Long-term results of artificial urinary sphincter implantation for urinary incontinence due to intrinsic sphincter deficiency in children.
Paret F, Leclair MD, Karam G, Rigaud J, Baron M, Perrouin-Verbe MA. Paret F, et al. Among authors: baron m. Neurourol Urodyn. 2023 Jan;42(1):355-365. doi: 10.1002/nau.25106. Epub 2022 Nov 26. Neurourol Urodyn. 2023. PMID: 36434815
PURPOSE: To report long-term results of artificial urinary sphincter implantation for urinary incontinence due to intrinsic sphincter deficiency in children. ...CONCLUSION: The artificial urinary sphincter is an effective long-term treatment for urinary incontinence …
PURPOSE: To report long-term results of artificial urinary sphincter implantation for urinary incontinence due to intrinsic sphincter …
Initial PCV Chemotherapy Followed by Radiotherapy Is Associated With a Prolonged Response But Late Neurotoxicity in 20 Diffuse Low-Grade Glioma Patients.
Blonski M, Obara T, Brzenczek C, Pouget C, Dillier C, Meyer M, Lavigne L, Forthoffer N, Broussois A, Gauchotte G, Baron MH, Rech F, Mézières S, Gaudeau Y, Verger A, Vogin G, Anxionnat R, Moureaux JM, Taillandier L. Blonski M, et al. Among authors: baron mh. Front Oncol. 2022 Mar 4;12:827897. doi: 10.3389/fonc.2022.827897. eCollection 2022. Front Oncol. 2022. PMID: 35311144 Free PMC article.
Radiological data were collected and included volume, velocity of diametric expansion (VDE), and MRI aspects. Long-term neurocognitive and QoL were analyzed. RESULTS: Twenty patients fulfilled the eligibility criteria. ...CONCLUSIONS: PCV-RT combination seems to have not o …
Radiological data were collected and included volume, velocity of diametric expansion (VDE), and MRI aspects. Long-term neurocognitiv …
A Bridge Too Far? Real-World Practice Patterns of Early Glucocorticoid Use in the Canadian Early Arthritis Cohort.
Andersen KM, Schieir O, Valois MF, Bartlett SJ, Bessette L, Boire G, Haraoui B, Hazlewood G, Hitchon C, Keystone EC, Pope J, Tin D, Throne JC, Bykerk VP; CATCH Investigators. Andersen KM, et al. ACR Open Rheumatol. 2022 Jan;4(1):57-64. doi: 10.1002/acr2.11334. Epub 2021 Oct 28. ACR Open Rheumatol. 2022. PMID: 34708574 Free PMC article.
Despite Canadian clinical practice guidelines to limit corticosteroid use to short-term or 'bridge' therapy, 30% of patients who used oral glucocorticoids still used them 2 years later. ...
Despite Canadian clinical practice guidelines to limit corticosteroid use to short-term or 'bridge' therapy, 30% of patients who used …
Long-term oncological safety of sentinel lymph node biopsy in early-stage cervical cancer: A post-hoc analysis of SENTICOL I and SENTICOL II cohorts.
Balaya V, Guani B, Morice P, Querleu D, Fourchotte V, Leblanc E, Daraï E, Baron M, Marret H, Levêque J, Magaud L, Mathevet P, Lécuru F; SENTICOL Group. Balaya V, et al. Among authors: baron m. Gynecol Oncol. 2022 Jan;164(1):53-61. doi: 10.1016/j.ygyno.2021.10.074. Epub 2021 Oct 23. Gynecol Oncol. 2022. PMID: 34696894 Free article.
Natural Killer Cells in Post-Transplant Lymphoproliferative Disorders.
Nakid-Cordero C, Baron M, Guihot A, Vieillard V. Nakid-Cordero C, et al. Among authors: baron m. Cancers (Basel). 2021 Apr 12;13(8):1836. doi: 10.3390/cancers13081836. Cancers (Basel). 2021. PMID: 33921413 Free PMC article. Review.
A general assumption is that PTLDs result from the impairment of anti-viral and anti-tumoral immunosurveillance due to the long-term use of immunosuppressants in transplant recipients. T cell impairment is known to play a critical role in the immune-pathogenesis of post-tr …
A general assumption is that PTLDs result from the impairment of anti-viral and anti-tumoral immunosurveillance due to the long-term …
Long-Term Toxicity and Health-Related Quality of Life After Adjuvant Chemoradiation Therapy or Radiation Therapy Alone for High-Risk Endometrial Cancer in the Randomized PORTEC-3 Trial.
Post CCB, de Boer SM, Powell ME, Mileshkin L, Katsaros D, Bessette P, Haie-Meder C, Ottevanger NPB, Ledermann JA, Khaw P, D'Amico R, Fyles A, Baron MH, Kitchener HC, Nijman HW, Lutgens LCHW, Brooks S, Jürgenliemk-Schulz IM, Feeney A, Goss G, Fossati R, Ghatage P, Leary A, Do V, Lissoni AA, McCormack M, Nout RA, Verhoeven-Adema KW, Smit VTHBM, Putter H, Creutzberg CL. Post CCB, et al. Among authors: baron mh. Int J Radiat Oncol Biol Phys. 2021 Mar 15;109(4):975-986. doi: 10.1016/j.ijrobp.2020.10.030. Epub 2020 Oct 28. Int J Radiat Oncol Biol Phys. 2021. PMID: 33129910 Free article. Clinical Trial.
PURPOSE: The survival results of the PORTEC-3 trial showed a significant improvement in both overall and failure-free survival with chemoradiation therapy versus pelvic radiation therapy alone. The present analysis was performed to compare long-term adverse events (AE) and …
PURPOSE: The survival results of the PORTEC-3 trial showed a significant improvement in both overall and failure-free survival with chemorad …
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