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Evaluating the impact of a hospital scale-up phase of a quality improvement intervention in Ghana on mortality for children under five.
Singh K, Speizer I, Barker PM, Agyeman-Duah JNA, Agula J, Akpakli JK, Akparibo S, Dasoberi IN, Kanyoke E, Steenwijk JH, Yabang E, Twum-Danso NAY, Sodzi-Tettey S. Singh K, et al. Among authors: barker pm. Int J Qual Health Care. 2019 Dec 31;31(10):752-758. doi: 10.1093/intqhc/mzz073. Int J Qual Health Care. 2019. PMID: 31322678
The multivariable interrupted time series analysis indicated that over the long-term the prompt provision of care change category was significantly associated with reduced postneonatal under five mortality (beta = -0.0024, 95% CI -0.0051, 0.0003, P < 0.10). ...
The multivariable interrupted time series analysis indicated that over the long-term the prompt provision of care change category was …
Using adapted quality-improvement approaches to strengthen community-based health systems and improve care in high HIV-burden sub-Saharan African countries.
Horwood CM, Youngleson MS, Moses E, Stern AF, Barker PM. Horwood CM, et al. Among authors: barker pm. AIDS. 2015 Jul;29 Suppl 2:S155-64. doi: 10.1097/QAD.0000000000000716. AIDS. 2015. PMID: 26102626
INTRODUCTION: Achieving long-term retention in HIV care is an important challenge for HIV management and achieving elimination of mother-to-child transmission. ...
INTRODUCTION: Achieving long-term retention in HIV care is an important challenge for HIV management and achieving elimination of mot …
Setting ART initiation targets in response to changing guidelines: The importance of addressing both steady-state and backlog.
Martin C, Naidoo NP, Venter WD, Jaffer A, Barker PM. Martin C, et al. Among authors: barker pm. S Afr Med J. 2014 May 12;104(6):428-30. doi: 10.7196/samj.7507. S Afr Med J. 2014. PMID: 25214253
CONCLUSION: South Africa has two pools of patients who need ART: the steady-state of HIV-infected patients entering the programme each year, determined by historical infection rates; and the backlog created by the shift in eligibility. The healthcare system needs to build long- …
CONCLUSION: South Africa has two pools of patients who need ART: the steady-state of HIV-infected patients entering the programme each year, …
Macrolide antibiotics for cystic fibrosis.
Southern KW, Barker PM, Solis-Moya A, Patel L. Southern KW, et al. Among authors: barker pm. Cochrane Database Syst Rev. 2012 Nov 14;11(11):CD002203. doi: 10.1002/14651858.CD002203.pub4. Cochrane Database Syst Rev. 2012. PMID: 23152214 Free PMC article. Updated. Review.
Treatment appeared safe over a six-month period; however, emergence of macrolide resistance was a concern. A multi-centre trial examining long-term effects of this antibiotic treatment is needed, especially for infants recognised through newborn screening....
Treatment appeared safe over a six-month period; however, emergence of macrolide resistance was a concern. A multi-centre trial examining lo …
Macrolide antibiotics for cystic fibrosis.
Southern KW, Barker PM, Solis-Moya A, Patel L. Southern KW, et al. Among authors: barker pm. Cochrane Database Syst Rev. 2011 Dec 7;(12):CD002203. doi: 10.1002/14651858.CD002203.pub3. Cochrane Database Syst Rev. 2011. PMID: 22161368 Updated. Review.
Treatment appeared safe over a six-month period; however, emergence of macrolide resistance was a concern. A multi-centre trial examining long-term effects of this antibiotic treatment is needed, especially for infants recognised through newborn screening....
Treatment appeared safe over a six-month period; however, emergence of macrolide resistance was a concern. A multi-centre trial examining lo …
Strategies for the scale-up of antiretroviral therapy in South Africa through health system optimization.
Barker PM, McCannon CJ, Mehta N, Green C, Youngleson MS, Yarrow J, Bennett B, Berwick DM. Barker PM, et al. J Infect Dis. 2007 Dec 1;196 Suppl 3:S457-63. doi: 10.1086/521110. J Infect Dis. 2007. PMID: 18181694 Review.
Although infusions of personnel, supplies, and diagnostics would make a major contribution to expanding the capacity to treat these diseases, the lack of these resources creates a long-term challenge, and there is a need for additional approaches to spread effective interv …
Although infusions of personnel, supplies, and diagnostics would make a major contribution to expanding the capacity to treat these diseases …
Sweat-testing in preterm and full-term infants less than 6 weeks of age.
Eng W, LeGrys VA, Schechter MS, Laughon MM, Barker PM. Eng W, et al. Among authors: barker pm. Pediatr Pulmonol. 2005 Jul;40(1):64-7. doi: 10.1002/ppul.20235. Pediatr Pulmonol. 2005. PMID: 15880420

Our objective was to examine the characteristics of preterm and full-term infants < or = 6 weeks old that influence the success of obtaining sufficient sweat for diagnosis of CF, and corresponding sweat chloride concentrations. A retrospective chart review of 119 sweat

…

Our objective was to examine the characteristics of preterm and full-term infants < or = 6 weeks old that influence the success of

…
Macrolide antibiotics for cystic fibrosis.
Southern KW, Barker PM, Solis A. Southern KW, et al. Among authors: barker pm. Cochrane Database Syst Rev. 2003;(3):CD002203. doi: 10.1002/14651858.CD002203. Cochrane Database Syst Rev. 2003. PMID: 12917924 Updated. Review.
REVIEWER'S CONCLUSIONS: The role of macrolides in the management of CF lung disease remains unclear and there are many unanswered questions. Two small randomised controlled trials have suggested short-term improvement in respiratory function with azithromycin. Until the re …
REVIEWER'S CONCLUSIONS: The role of macrolides in the management of CF lung disease remains unclear and there are many unanswered questions. …
Effects of adenosine, ATP, and UTP on chloride secretion by epithelia explanted from fetal rat lung.
Barker PM, Gatzy JT. Barker PM, et al. Pediatr Res. 1998 May;43(5):652-9. doi: 10.1203/00006450-199805000-00014. Pediatr Res. 1998. PMID: 9585012
We looked for evidence for P1 and P2 receptors that mediate Cl- secretion in 14-d distal lungs and 14- and 18-d tracheas explanted from fetal rats (term = 22 d). We measured amiloride-insensitive transepithelial voltage changes induced by ATP, UTP, or adenosine. ...
We looked for evidence for P1 and P2 receptors that mediate Cl- secretion in 14-d distal lungs and 14- and 18-d tracheas explanted from feta …
Effect of gas composition on liquid secretion by explants of distal lung of fetal rat in submersion culture.
Barker PM, Gatzy JT. Barker PM, et al. Am J Physiol. 1993 Nov;265(5 Pt 1):L512-7. doi: 10.1152/ajplung.1993.265.5.L512. Am J Physiol. 1993. PMID: 8238540
We studied effects of "fetal" (3% O2-8% CO2) and "postnatal" (21% O2-5% CO2) gas tensions and of low hormone concentrations [media with 10% charcoal-stripped fetal bovine serum (stFBS) or unstripped FBS] on water content and morphology of distal lung explanted from 14-, 20-, and …
We studied effects of "fetal" (3% O2-8% CO2) and "postnatal" (21% O2-5% CO2) gas tensions and of low hormone concentrations [media with 10% …
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