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Hyperprogressors after Immunotherapy: Analysis of Genomic Alterations Associated with Accelerated Growth Rate.
Kato S, Goodman A, Walavalkar V, Barkauskas DA, Sharabi A, Kurzrock R. Kato S, et al. Among authors: barkauskas da. Clin Cancer Res. 2017 Aug 1;23(15):4242-4250. doi: 10.1158/1078-0432.CCR-16-3133. Epub 2017 Mar 28. Clin Cancer Res. 2017. PMID: 28351930 Free PMC article.
Purpose: Checkpoint inhibitors demonstrate salutary anticancer effects, including long-term remissions. PD-L1 expression/amplification, high mutational burden, and mismatch repair deficiency correlate with response. ...
Purpose: Checkpoint inhibitors demonstrate salutary anticancer effects, including long-term remissions. PD-L1 expression/amplificatio …
The cumulative effect of different childhood trauma types on self-reported symptoms of adult male depression and PTSD, substance abuse and health-related quality of life in a large active-duty military cohort.
Agorastos A, Pittman JO, Angkaw AC, Nievergelt CM, Hansen CJ, Aversa LH, Parisi SA, Barkauskas DA; Marine Resiliency Study Team; Baker DG. Agorastos A, et al. Among authors: barkauskas da. J Psychiatr Res. 2014 Nov;58:46-54. doi: 10.1016/j.jpsychires.2014.07.014. Epub 2014 Aug 4. J Psychiatr Res. 2014. PMID: 25139009
History of childhood trauma (CT) is highly prevalent and may lead to long-term consequences on physical and mental health. This study investigated the independent association of CT with symptoms of adult depression and posttraumatic stress disorder (PTSD), mental and physi …
History of childhood trauma (CT) is highly prevalent and may lead to long-term consequences on physical and mental health. This study …
Phase II trial of trastuzumab in combination with cytotoxic chemotherapy for treatment of metastatic osteosarcoma with human epidermal growth factor receptor 2 overexpression: a report from the children's oncology group.
Ebb D, Meyers P, Grier H, Bernstein M, Gorlick R, Lipshultz SE, Krailo M, Devidas M, Barkauskas DA, Siegal GP, Ferguson WS, Letson GD, Marcus K, Goorin A, Beardsley P, Marina N. Ebb D, et al. Among authors: barkauskas da. J Clin Oncol. 2012 Jul 10;30(20):2545-51. doi: 10.1200/JCO.2011.37.4546. Epub 2012 Jun 4. J Clin Oncol. 2012. PMID: 22665540 Free PMC article. Clinical Trial.
For patients without HER2 overexpression, treated with chemotherapy alone, the 30-month event-free and overall survival rates were 32% and 50%, respectively. There was no clinically significant short-term cardiotoxicity in patients treated with trastuzumab and doxorubicin. …
For patients without HER2 overexpression, treated with chemotherapy alone, the 30-month event-free and overall survival rates were 32% and 5 …