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Development of Frail RISC-HIV: a Risk Score for Predicting Frailty Risk in the Short-term for Care of People with HIV.
Ruderman SA, Nance RM, Drumright LN, Whitney BM, Hahn AW, Ma J, Haidar L, Eltonsy S, Mayer KH, Eron JJ, Greene M, Mathews WC, Webel A, Saag MS, Willig AL, Kamen C, McCaul M, Chander G, Cachay E, Lober WB, Pandya C, Cartujano-Barrera F, Kritchevsky SB, Austad SN, Landay A, Kitahata MM, Crane HM, Delaney JAC. Ruderman SA, et al. Among authors: austad sn. AIDS. 2023 May 1;37(6):967-975. doi: 10.1097/QAD.0000000000003501. Epub 2023 Jan 31. AIDS. 2023. PMID: 36723488
OBJECTIVE: Frailty is common among people with HIV (PWH), so we developed frail risk in the short-term for care (RISC)-HIV, a frailty prediction risk score for HIV clinical decision-making. DESIGN: We followed PWH for up to 2 years to identify short-term predictors …
OBJECTIVE: Frailty is common among people with HIV (PWH), so we developed frail risk in the short-term for care (RISC)-HIV, a frailty …
Senescence in natural populations of animals: widespread evidence and its implications for bio-gerontology.
Nussey DH, Froy H, Lemaitre JF, Gaillard JM, Austad SN. Nussey DH, et al. Among authors: austad sn. Ageing Res Rev. 2013 Jan;12(1):214-25. doi: 10.1016/j.arr.2012.07.004. Epub 2012 Aug 4. Ageing Res Rev. 2013. PMID: 22884974 Free PMC article. Review.
We identify the roots of this fallacy in the otherwise seminal works of Medawar and Comfort, and explain that under antagonistic pleiotropy or disposable soma explanations for the evolution of senescence there is no reason why senescence cannot evolve to be manifest within the li …
We identify the roots of this fallacy in the otherwise seminal works of Medawar and Comfort, and explain that under antagonistic pleiotropy …
An experimental paradigm for the study of slowly aging organisms.
Austad SN. Austad SN. Exp Gerontol. 2001 Apr;36(4-6):599-605. doi: 10.1016/s0531-5565(00)00229-1. Exp Gerontol. 2001. PMID: 11295502 Review.
The advantage of this paradigm is that it requires neither the long-term monitoring of individuals nor the use of exceptionally old individuals. ...
The advantage of this paradigm is that it requires neither the long-term monitoring of individuals nor the use of exceptionally old i …
The evolution of the antiaging action of dietary restriction: a hypothesis.
Masoro EJ, Austad SN. Masoro EJ, et al. Among authors: austad sn. J Gerontol A Biol Sci Med Sci. 1996 Nov;51(6):B387-91. doi: 10.1093/gerona/51a.6.b387. J Gerontol A Biol Sci Med Sci. 1996. PMID: 8914486
We hypothesize that this DR response arose because of its evolutionary advantage with respect to survival during periods of unpredictable, short-term food shortage. In our evolutionary scenario, food shortage led to an adaptive redirection of resources away from reproducti …
We hypothesize that this DR response arose because of its evolutionary advantage with respect to survival during periods of unpredictable, s …