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CPR compression strategy 30:2 is difficult to adhere to, but has better survival than continuous chest compressions when done correctly.
Schmicker RH, Nichol G, Kudenchuk P, Christenson J, Vaillancourt C, Wang HE, Aufderheide TP, Idris AH, Daya MR. Schmicker RH, et al. Among authors: aufderheide tp. Resuscitation. 2021 Aug;165:31-37. doi: 10.1016/j.resuscitation.2021.05.027. Epub 2021 Jun 5. Resuscitation. 2021. PMID: 34098033 Free PMC article.
Effect modification with intended strategy was assessed through a multiplicative interaction term. RESULTS: Included were 26,810 adults with out of hospital cardiac arrest, of which 10,942 had an intended strategy of 30:2 and 15,868 an intended strategy of CCC. ...
Effect modification with intended strategy was assessed through a multiplicative interaction term. RESULTS: Included were 26,810 adul …
Long-Term Prognostic Value of Gasping During Out-of-Hospital Cardiac Arrest.
Debaty G, Labarere J, Frascone RJ, Wayne MA, Swor RA, Mahoney BD, Domeier RM, Olinger ML, O'Neil BJ, Yannopoulos D, Aufderheide TP, Lurie KG. Debaty G, et al. Among authors: aufderheide tp. J Am Coll Cardiol. 2017 Sep 19;70(12):1467-1476. doi: 10.1016/j.jacc.2017.07.782. J Am Coll Cardiol. 2017. PMID: 28911510 Free article. Clinical Trial.
Sodium nitroprusside enhanced cardiopulmonary resuscitation improves short term survival in a porcine model of ischemic refractory ventricular fibrillation.
Yannopoulos D, Bartos JA, George SA, Sideris G, Voicu S, Oestreich B, Matsuura T, Shekar K, Rees J, Aufderheide TP. Yannopoulos D, et al. Among authors: aufderheide tp. Resuscitation. 2017 Jan;110:6-11. doi: 10.1016/j.resuscitation.2016.09.032. Epub 2016 Oct 19. Resuscitation. 2017. PMID: 27771299 Free PMC article.
We developed a new, coronary occlusion/ischemia model of prolonged resuscitation, mimicking the majority of out-of-hospital cardiac arrests presenting with shockable rhythms. HYPOTHESIS: SNPeCPR will increase short term (4-h) survival compared to standard 2015 Advanced Car …
We developed a new, coronary occlusion/ischemia model of prolonged resuscitation, mimicking the majority of out-of-hospital cardiac arrests …
The association of health status and providing consent to continued participation in an out-of-hospital cardiac arrest trial performed under exception from informed consent.
Salzman JG, Frascone RJ, Burkhart N, Holcomb R, Wewerka SS, Swor RA, Mahoney BD, Wayne MA, Domeier RM, Olinger ML, Aufderheide TP, Lurie KG. Salzman JG, et al. Among authors: aufderheide tp. Acad Emerg Med. 2015 Mar;22(3):347-53. doi: 10.1111/acem.12613. Epub 2015 Feb 25. Acad Emerg Med. 2015. PMID: 25716210 Free article. Clinical Trial.
Although prospective individual consent is not required for studies conducted under this regulation, consent from a legally authorized representative (LAR) or the patient at the earliest feasible opportunity is required to obtain short- and long-term outcome data. The obje …
Although prospective individual consent is not required for studies conducted under this regulation, consent from a legally authorized repre …
One-year outcomes of out-of-hospital administration of intravenous glucose, insulin, and potassium (GIK) in patients with suspected acute coronary syndromes (from the IMMEDIATE [Immediate Myocardial Metabolic Enhancement During Initial Assessment and Treatment in Emergency Care] Trial).
Selker HP, Udelson JE, Massaro JM, Ruthazer R, D'Agostino RB, Griffith JL, Sheehan PR, Desvigne-Nickens P, Rosenberg Y, Tian X, Vickery EM, Atkins JM, Aufderheide TP, Sayah AJ, Pirrallo RG, Levy MK, Richards ME, Braude DA, Doyle DD, Frascone RJ, Kosiak DJ, Leaming JM, Van Gelder CM, Walter GP, Wayne MA, Woolard RH, Beshansky JR. Selker HP, et al. Among authors: aufderheide tp. Am J Cardiol. 2014 May 15;113(10):1599-605. doi: 10.1016/j.amjcard.2014.02.010. Epub 2014 Mar 1. Am J Cardiol. 2014. PMID: 24792735 Free PMC article. Clinical Trial.
The Immediate Myocardial Metabolic Enhancement During Initial Assessment and Treatment in Emergency care Trial of very early intravenous glucose-insulin-potassium (GIK) for acute coronary syndromes (ACS) in out-of-hospital emergency medical service (EMS) settings showed 80% reduc …
The Immediate Myocardial Metabolic Enhancement During Initial Assessment and Treatment in Emergency care Trial of very early intravenous glu …
Primary outcomes for resuscitation science studies: a consensus statement from the American Heart Association.
Becker LB, Aufderheide TP, Geocadin RG, Callaway CW, Lazar RM, Donnino MW, Nadkarni VM, Abella BS, Adrie C, Berg RA, Merchant RM, O'Connor RE, Meltzer DO, Holm MB, Longstreth WT, Halperin HR; American Heart Association Emergency Cardiovascular Care Committee; Council on Cardiopulmonary, Critical Care, Perioperative and Resuscitation. Becker LB, et al. Among authors: aufderheide tp. Circulation. 2011 Nov 8;124(19):2158-77. doi: 10.1161/CIR.0b013e3182340239. Epub 2011 Oct 3. Circulation. 2011. PMID: 21969010 Free PMC article.
For large trials designed to have a major impact on public health policy, longer-term end points such as 90 days coupled with neurocognitive and quality-of-life assessments should be considered, as should the additional costs of this approach. ...
For large trials designed to have a major impact on public health policy, longer-term end points such as 90 days coupled with neuroco …
Standard cardiopulmonary resuscitation versus active compression-decompression cardiopulmonary resuscitation with augmentation of negative intrathoracic pressure for out-of-hospital cardiac arrest: a randomised trial.
Aufderheide TP, Frascone RJ, Wayne MA, Mahoney BD, Swor RA, Domeier RM, Olinger ML, Holcomb RG, Tupper DE, Yannopoulos D, Lurie KG. Aufderheide TP, et al. Lancet. 2011 Jan 22;377(9762):301-11. doi: 10.1016/S0140-6736(10)62103-4. Lancet. 2011. PMID: 21251705 Free PMC article. Clinical Trial.
INTERPRETATION: On the basis of our findings showing increased effectiveness and generalisability of the study intervention, active compression-decompression CPR with augmentation of negative intrathoracic pressure should be considered as an alternative to standard CPR to increas …
INTERPRETATION: On the basis of our findings showing increased effectiveness and generalisability of the study intervention, active compress …
Do emergency department patients with possible acute coronary syndrome have better outcomes when admitted to cardiology versus other services?
Katz DA, Aufderheide TP, Bogner M, Rahko PS, Hillis SL, Selker HP. Katz DA, et al. Among authors: aufderheide tp. Ann Emerg Med. 2008 May;51(5):561-70, 570.e1. doi: 10.1016/j.annemergmed.2007.05.016. Epub 2007 Aug 31. Ann Emerg Med. 2008. PMID: 17764781 Free PMC article.
CONCLUSION: ED patients admitted for evaluation of possible acute coronary syndrome do not experience worsened short-term outcomes if admitted to a noncardiology service bed....
CONCLUSION: ED patients admitted for evaluation of possible acute coronary syndrome do not experience worsened short-term outcomes if …
Does concordance with guideline triage recommendations affect clinical care of patients with possible acute coronary syndrome?
Katz DA, Dawson J, Beshansky JR, Rahko PS, Aufderheide TP, Bogner M, Tighouart H, Selker HP. Katz DA, et al. Among authors: aufderheide tp. Med Decis Making. 2007 Jul-Aug;27(4):423-37. doi: 10.1177/0272989X07302557. Epub 2007 Jul 19. Med Decis Making. 2007. PMID: 17641142
BACKGROUND: The Agency for Health Care Policy and Research (AHCPR) Unstable Angina Practice Guideline recommends outpatient management for patients at low risk and admission to a monitored bed for patients at intermediate-high risk of adverse short-term outcomes, but the c …
BACKGROUND: The Agency for Health Care Policy and Research (AHCPR) Unstable Angina Practice Guideline recommends outpatient management for p …
Retention of CPR skills learned in a traditional AHA Heartsaver course versus 30-min video self-training: a controlled randomized study.
Einspruch EL, Lynch B, Aufderheide TP, Nichol G, Becker L. Einspruch EL, et al. Among authors: aufderheide tp. Resuscitation. 2007 Sep;74(3):476-86. doi: 10.1016/j.resuscitation.2007.01.030. Epub 2007 Apr 17. Resuscitation. 2007. PMID: 17442479 Clinical Trial.
Training with a brief video self-instruction (VSI) program has shown that this type of training can produce short-term skill performance at least as good as that seen with traditional American Heart Association (AHA) Heartsaver training, although it is unclear whether ther …
Training with a brief video self-instruction (VSI) program has shown that this type of training can produce short-term skill performa …
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