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The costs and benefits of fast living.
Rose KE, Atkinson RL, Turnbull LA, Rees M. Rose KE, et al. Among authors: atkinson rl. Ecol Lett. 2009 Dec;12(12):1379-84. doi: 10.1111/j.1461-0248.2009.01394.x. Epub 2009 Oct 28. Ecol Lett. 2009. PMID: 19874384
This is because (1) growth rate typically declines with size and yet the most widely used growth measure - relative growth rate or RGR (conventionally measured as the log of the ratio of successive sizes divided by the time interval) - is not size-corrected and so confounds growt …
This is because (1) growth rate typically declines with size and yet the most widely used growth measure - relative growth rate or RGR (conv …
Comparison of combinations of drugs for treatment of obesity: body weight and echocardiographic status.
Whigham LD, Dhurandhar NV, Rahko PS, Atkinson RL. Whigham LD, et al. Among authors: atkinson rl. Int J Obes (Lond). 2007 May;31(5):850-7. doi: 10.1038/sj.ijo.0803498. Epub 2006 Dec 5. Int J Obes (Lond). 2007. PMID: 17146452
CONCLUSIONS: The combination of phentermine and fluoxetine was not as effective as phen-fen, but was not associated with cardiac valve lesions. Longer term, larger scale studies of phen-flu are warranted....
CONCLUSIONS: The combination of phentermine and fluoxetine was not as effective as phen-fen, but was not associated with cardiac valve lesio …
Safety profile of conjugated linoleic acid in a 12-month trial in obese humans.
Whigham LD, O'Shea M, Mohede IC, Walaski HP, Atkinson RL. Whigham LD, et al. Among authors: atkinson rl. Food Chem Toxicol. 2004 Oct;42(10):1701-9. doi: 10.1016/j.fct.2004.06.008. Food Chem Toxicol. 2004. PMID: 15354322 Clinical Trial.
Conjugated linoleic acid (CLA) is marketed in numerous commercially available dietary supplements, but few studies have looked at the long-term safety of this product. The current study evaluated the safety of one CLA product (Clarinol) over a one-year period in obese huma …
Conjugated linoleic acid (CLA) is marketed in numerous commercially available dietary supplements, but few studies have looked at the long- …
Long-term pharmacologic treatment of morbid obesity in a community practice.
Spitz AF, Schumacher D, Blank RC, Dhurandhar NV, Atkinson RL. Spitz AF, et al. Among authors: atkinson rl. Endocr Pract. 1997 Sep-Oct;3(5):269-75. doi: 10.4158/EP.3.5.269. Endocr Pract. 1997. PMID: 15251779
Moreover, statistically significant changes were noted in metabolic variables associated with risk of heart disease. Future efforts must focus on methods to improve long-term compliance....
Moreover, statistically significant changes were noted in metabolic variables associated with risk of heart disease. Future efforts must foc …
Weight loss with self-help compared with a structured commercial program: a randomized trial.
Heshka S, Anderson JW, Atkinson RL, Greenway FL, Hill JO, Phinney SD, Kolotkin RL, Miller-Kovach K, Pi-Sunyer FX. Heshka S, et al. Among authors: atkinson rl. JAMA. 2003 Apr 9;289(14):1792-8. doi: 10.1001/jama.289.14.1792. JAMA. 2003. PMID: 12684357 Clinical Trial.
CONTEXT: Although commercial weight loss programs provide treatment to millions of clients, their efficacy has not been evaluated in rigorous long-term trials. OBJECTIVE: To compare weight loss and health benefits achieved and maintained through self-help weight loss vs wi …
CONTEXT: Although commercial weight loss programs provide treatment to millions of clients, their efficacy has not been evaluated in rigorou …
An association of elevated serum gonadotropin concentrations and Alzheimer disease?
Bowen RL, Isley JP, Atkinson RL. Bowen RL, et al. Among authors: atkinson rl. J Neuroendocrinol. 2000 Apr;12(4):351-4. doi: 10.1046/j.1365-2826.2000.00461.x. J Neuroendocrinol. 2000. PMID: 10718932
Circulating concentrations of follicle stimulating hormone (FSH) and luteinizing hormone (LH) levels in 40 male residents of long-term care facilities with the primary diagnosis of dementia were compared to 29 age-matched controls. ...
Circulating concentrations of follicle stimulating hormone (FSH) and luteinizing hormone (LH) levels in 40 male residents of long-term
Initial weight loss as a predictor of response to obesity drugs.
Dhurandhar NV, Blank RC, Schumacher D, Atkinson RL. Dhurandhar NV, et al. Among authors: atkinson rl. Int J Obes Relat Metab Disord. 1999 Dec;23(12):1333-6. doi: 10.1038/sj.ijo.0801111. Int J Obes Relat Metab Disord. 1999. PMID: 10643693 Clinical Trial.
BACKGROUND: Initial weight loss has been used as a predictor of long-term response to obesity drugs. Discontinuation of drugs has been recommended if weight loss is not > or =1.81 kg (4 lb) in the first month of treatment. ...CONCLUSIONS: Although, the first month weigh …
BACKGROUND: Initial weight loss has been used as a predictor of long-term response to obesity drugs. Discontinuation of drugs has bee …
Evaluation of a rat model of valproate-induced obesity.
Wolden-Hanson T, Gidal BE, Atkinson RL. Wolden-Hanson T, et al. Among authors: atkinson rl. Pharmacotherapy. 1998 Sep-Oct;18(5):1075-81. Pharmacotherapy. 1998. PMID: 9758318
Long-term treatment with the anticonvulsant valproate (VPA) leads to well-documented weight gain and obesity in humans. ...
Long-term treatment with the anticonvulsant valproate (VPA) leads to well-documented weight gain and obesity in humans. ...
Long-term drug treatment of obesity in a private practice setting.
Atkinson RL, Blank RC, Schumacher D, Dhurandhar NV, Ritch DL. Atkinson RL, et al. Obes Res. 1997 Nov;5(6):578-86. doi: 10.1002/j.1550-8528.1997.tb00579.x. Obes Res. 1997. PMID: 9449143 Free article.
This study evaluated the long-term efficacy and safety of the combination of phentermine and fenfluramine for the treatment of obesity in a private practice setting. ...Adverse events were modest. We conclude that, in a private practice setting, long-term treatment …
This study evaluated the long-term efficacy and safety of the combination of phentermine and fenfluramine for the treatment of obesit …
Use of drugs in the treatment of obesity.
Atkinson RL. Atkinson RL. Annu Rev Nutr. 1997;17:383-403. doi: 10.1146/annurev.nutr.17.1.383. Annu Rev Nutr. 1997. PMID: 9240933 Review.
Diet, exercise, and behavioral modification of lifestyle are rarely successful over the long term. Medications have been used sparingly, because of concerns about addiction and ineffectiveness, but used chronically, obesity drugs are effective. ...
Diet, exercise, and behavioral modification of lifestyle are rarely successful over the long term. Medications have been used sparing …
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