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Early diagnosis from newborn screening maximises survival in severe cystic fibrosis.
Tridello G, Castellani C, Meneghelli I, Tamanini A, Assael BM. Tridello G, et al. Among authors: assael bm. ERJ Open Res. 2018 Apr 20;4(2):00109-2017. doi: 10.1183/23120541.00109-2017. eCollection 2018 Apr. ERJ Open Res. 2018. PMID: 29692998 Free PMC article.
Newborn screening (NBS) for cystic fibrosis (CF) has been gradually established in several countries, but scant data are available on its long-term effects on survival. Our objective was to evaluate the long-term effects of CF NBS on survival. 586 patients, diagnose …
Newborn screening (NBS) for cystic fibrosis (CF) has been gradually established in several countries, but scant data are available on its lo …
[Italian Cystic Fibrosis Registry. Report 2011-2014].
Giordani B, Amato A, Majo F, Ferrari G, Quattrucci S, Minicucci L, Padoan R, Floridia G, Puppo Fornaro G, Taruscio D, Salvatore M; Gruppo di lavoro RIFC. Giordani B, et al. Epidemiol Prev. 2018 Jan-Feb;42(1S1):1-32. doi: 10.19191/EP18.1-S1.P001.001. Epidemiol Prev. 2018. PMID: 29506377 Free article. Italian.
In particular, the Report should contribute to the following objectives: - to analyze the medium and long-term clinical and epidemiological trends of the disease; - to identify the main healthcare needs at regional and national level in order to contribute to the healthcar …
In particular, the Report should contribute to the following objectives: - to analyze the medium and long-term clinical and epidemiol …
Hemodynamic predictors of long term survival in end stage cystic fibrosis.
Scarsini R, Prioli MA, Milano EG, Castellani C, Pesarini G, Assael BM, Vassanelli C, Ribichini FL. Scarsini R, et al. Among authors: assael bm. Int J Cardiol. 2016 Jan 1;202:221-5. doi: 10.1016/j.ijcard.2015.09.009. Epub 2015 Sep 12. Int J Cardiol. 2016. PMID: 26397415
The aim of this study is to investigate whether PAC is a predictor of long-term prognosis in a population of CF patients affected by advanced lung disease. ...An impaired PAC (1.95 ml/mmHg) was a strong independent predictor of long-term mortality (HR 3.44: 95% CI 1 …
The aim of this study is to investigate whether PAC is a predictor of long-term prognosis in a population of CF patients affected by …
Treatment of low bone density in young people with cystic fibrosis: a multicentre, prospective, open-label observational study of calcium and calcifediol followed by a randomised placebo-controlled trial of alendronate.
Bianchi ML, Colombo C, Assael BM, Dubini A, Lombardo M, Quattrucci S, Bella S, Collura M, Messore B, Raia V, Poli F, Bini R, Albanese CV, De Rose V, Costantini D, Romano G, Pustorino E, Magazzù G, Bertasi S, Lucidi V, Traverso G, Coruzzo A, Grzejdziak AD. Bianchi ML, et al. Among authors: assael bm. Lancet Respir Med. 2013 Jul;1(5):377-85. doi: 10.1016/S2213-2600(13)70064-X. Epub 2013 Jun 2. Lancet Respir Med. 2013. PMID: 24429202 Clinical Trial.
BACKGROUND: Long-term complications of cystic fibrosis include osteoporosis and fragility fractures, but few data are available about effective treatment strategies, especially in young patients. ...
BACKGROUND: Long-term complications of cystic fibrosis include osteoporosis and fragility fractures, but few data are available about …
Small airway deposition of dornase alfa during exacerbations in cystic fibrosis; a randomized controlled clinical trial.
Bakker EM, Volpi S, Salonini E, Müllinger B, Kroneberg P, Bakker M, Hop WC, Assael BM, Tiddens HA. Bakker EM, et al. Among authors: assael bm. Pediatr Pulmonol. 2014 Feb;49(2):154-61. doi: 10.1002/ppul.22800. Epub 2013 Jul 3. Pediatr Pulmonol. 2014. PMID: 23913868 Clinical Trial.
Additionally, many CF patients lose lung function in the long term as a result of respiratory tract exacerbations (RTEs). No trials have been performed to optimize mucolytic therapy during a RTE. ...
Additionally, many CF patients lose lung function in the long term as a result of respiratory tract exacerbations (RTEs). No trials h …
Hyaluronic acid improves the tolerability of hypertonic saline in the chronic treatment of cystic fibrosis patients: a multicenter, randomized, controlled clinical trial.
Ros M, Casciaro R, Lucca F, Troiani P, Salonini E, Favilli F, Quattrucci S, Sher D, Assael BM. Ros M, et al. Among authors: assael bm. J Aerosol Med Pulm Drug Deliv. 2014 Apr;27(2):133-7. doi: 10.1089/jamp.2012.1034. Epub 2013 Jun 8. J Aerosol Med Pulm Drug Deliv. 2014. PMID: 23745525 Clinical Trial.
The addition of HA to HS reduces the prevalence and severity of cough, throat irritation, and saltiness and may improve compliance in patients who previously did not tolerate HS well on its own. Longer-term studies could further assess the benefit of chronic treatment....
The addition of HA to HS reduces the prevalence and severity of cough, throat irritation, and saltiness and may improve compliance in patien …
Growth and long-term lung function in cystic fibrosis: a longitudinal study of patients diagnosed by neonatal screening.
Assael BM, Casazza G, Iansa P, Volpi S, Milani S. Assael BM, et al. Pediatr Pulmonol. 2009 Mar;44(3):209-15. doi: 10.1002/ppul.21001. Pediatr Pulmonol. 2009. PMID: 19230003
OBJECTIVE: So far there is no long-term analysis relating the achievement of growth milestones (such as prepubertal and pubertal take-off and peak velocity) to the course of respiratory function from childhood to adulthood in cystic fibrosis. ...
OBJECTIVE: So far there is no long-term analysis relating the achievement of growth milestones (such as prepubertal and pubertal take …
Chest physiotherapy with positive airway pressure: a pilot study of short-term effects on sputum clearance in patients with cystic fibrosis and severe airway obstruction.
Placidi G, Cornacchia M, Polese G, Zanolla L, Assael BM, Braggion C. Placidi G, et al. Among authors: assael bm. Respir Care. 2006 Oct;51(10):1145-53. Respir Care. 2006. PMID: 17005060 Free article. Clinical Trial.
BACKGROUND: The periodic administration of positive airway pressure combined with directed cough could aid mucus clearance in patients with cystic fibrosis (CF) and severe airway obstruction. OBJECTIVE: To compare the short-term effect of positive expiratory pressure (PEP) …
BACKGROUND: The periodic administration of positive airway pressure combined with directed cough could aid mucus clearance in patients with …
Liver transplant in cystic fibrosis: a poll among European centers. A study from the European Liver Transplant Registry.
Melzi ML, Kelly DA, Colombo C, Jara P, Manzanares J, Colledan M, Strazzabosco M, DeLorenzo P, Valsecchi MG, Adam R, Gridelli B, Assael BM; EGSLTCF; European Liver Transplant Association (ELTA); European Cystic Fibrosis Society (ECFS). Melzi ML, et al. Among authors: assael bm. Transpl Int. 2006 Sep;19(9):726-31. doi: 10.1111/j.1432-2277.2006.00344.x. Transpl Int. 2006. PMID: 16918533 Free article.
Poor respiratory function was the main risk factor for early death. In the short-term, respiratory function significantly improved after LTx. LTx is the appropriate treatment for patients with advanced CF-related liver disease and preserved pulmonary function (Forced Expir …
Poor respiratory function was the main risk factor for early death. In the short-term, respiratory function significantly improved af …
Early antibiotic treatment of pseudomonas aeruginosa colonisation in cystic fibrosis: a critical review of the literature.
Marchetti F, Giglio L, Candusso M, Faraguna D, Assael BM. Marchetti F, et al. Among authors: assael bm. Eur J Clin Pharmacol. 2004 Apr;60(2):67-74. doi: 10.1007/s00228-004-0735-2. Epub 2004 Mar 5. Eur J Clin Pharmacol. 2004. PMID: 15004732 Review.
The short follow-up did not allow definite conclusions with regard to the long-term progression of respiratory insufficiency or survival. CONCLUSIONS: Evidence was found that antibiotic treatment can reduce the rate of positive cultures and of anti-PA antibody titres in as …
The short follow-up did not allow definite conclusions with regard to the long-term progression of respiratory insufficiency or survi …
17 results