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Atrial Fibrillation In Patients With Stroke Attributed to Large- or Small-Vessel Disease: 3-Year Results From the STROKE AF Randomized Clinical Trial.
Bernstein RA, Kamel H, Granger CB, Piccini JP, Katz JM, Sethi PP, Pouliot E, Franco N, Ziegler PD, Schwamm LH; STROKE AF Investigators. Bernstein RA, et al. JAMA Neurol. 2023 Dec 1;80(12):1277-1283. doi: 10.1001/jamaneurol.2023.3931. JAMA Neurol. 2023. PMID: 37902733 Free PMC article.
INTERVENTIONS: ICM monitoring vs site-specific usual care. MAIN OUTCOMES AND MEASURES: The prespecified long-term outcome of the trial was AF detection through study follow-up (up to 3 years). ...
INTERVENTIONS: ICM monitoring vs site-specific usual care. MAIN OUTCOMES AND MEASURES: The prespecified long-term outcome of the tria …
Determinants and Temporal Trends of Dual Antiplatelet Therapy After Mild Noncardioembolic Stroke.
Del Brutto VJ, Yin R, Gardener H, Ying H, Gutierrez CM, Jameson AM, Rose DZ, Alkhachroum A, Foster D, Dong C, Ancheta S, Sur NB, Gordon Perue G, Rundek T, Asdaghi N, Sacco RL, Romano JG. Del Brutto VJ, et al. Among authors: asdaghi n. Stroke. 2023 Oct;54(10):2552-2561. doi: 10.1161/STROKEAHA.123.043769. Epub 2023 Sep 7. Stroke. 2023. PMID: 37675611
BACKGROUND: Short-term dual antiplatelet therapy (DAPT) reduces early stroke recurrence after mild noncardioembolic ischemic stroke (NCIS). ...
BACKGROUND: Short-term dual antiplatelet therapy (DAPT) reduces early stroke recurrence after mild noncardioembolic ischemic stroke ( …
Direct Bypass Surgery for Moyamoya and Steno-occlusive Vasculopathy: Clinical Outcomes, Intraoperative Blood Flow Analysis, Long-term Follow-up, and Long-term Bypass Patency in a Single Surgeon Case Series of 162 Procedures.
Khan NR, Elarjani T, Jamshidi AM, Lu VM, Silva MA, Richardson A, Harrington T, Valdes T, Campo N, Krementz N, Asdaghi N, Sur N, Londono EM, Malik AM, Koch S, Romano J, Morcos JJ. Khan NR, et al. Among authors: asdaghi n. World Neurosurg. 2022 Dec;168:e500-e517. doi: 10.1016/j.wneu.2022.10.015. Epub 2022 Oct 7. World Neurosurg. 2022. PMID: 36216248 Review.
We sought to determine clinical outcomes, intraoperative blood flow analysis, long term follow up, and long term patency rates from a single surgeon's series of direct cerebral bypass for moyamoya disease, moyamoya syndrome, and steno-occlusive disease. METHODS: We …
We sought to determine clinical outcomes, intraoperative blood flow analysis, long term follow up, and long term patency rates …
Endovascular Treatment and Thrombolysis for Acute Ischemic Stroke in Patients With Premorbid Disability or Dementia: A Scientific Statement From the American Heart Association/American Stroke Association.
Ganesh A, Fraser JF, Gordon Perue GL, Amin-Hanjani S, Leslie-Mazwi TM, Greenberg SM, Couillard P, Asdaghi N, Goyal M; American Heart Association Stroke Council. Ganesh A, et al. Among authors: asdaghi n. Stroke. 2022 May;53(5):e204-e217. doi: 10.1161/STR.0000000000000406. Epub 2022 Mar 28. Stroke. 2022. PMID: 35343235 Free article. Review.
Recent clinical-epidemiological studies have demonstrated challenges in our concept and measurement of premorbid disability or dementia while highlighting the significant proportion of the general stroke population that falls under this umbrella, risking exclusion from therapies. …
Recent clinical-epidemiological studies have demonstrated challenges in our concept and measurement of premorbid disability or dementia whil …
Effect of Long-term Continuous Cardiac Monitoring vs Usual Care on Detection of Atrial Fibrillation in Patients With Stroke Attributed to Large- or Small-Vessel Disease: The STROKE-AF Randomized Clinical Trial.
Bernstein RA, Kamel H, Granger CB, Piccini JP, Sethi PP, Katz JM, Vives CA, Ziegler PD, Franco NC, Schwamm LH; STROKE-AF Investigators. Bernstein RA, et al. JAMA. 2021 Jun 1;325(21):2169-2177. doi: 10.1001/jama.2021.6470. JAMA. 2021. PMID: 34061145 Free PMC article. Clinical Trial.
IMPORTANCE: Patients with ischemic stroke attributed to large- or small-vessel disease are not considered at high risk for atrial fibrillation (AF), and the AF incidence rate in this population is unknown. OBJECTIVES: To determine whether long-term cardiac monitoring is mo …
IMPORTANCE: Patients with ischemic stroke attributed to large- or small-vessel disease are not considered at high risk for atrial fibrillati …
Adherence to Acute Care Measures Affects Mortality in Patients with Ischemic Stroke: The Florida Stroke Registry.
Gardener H, Rundek T, Lichtman J, Leifheit E, Wang K, Asdaghi N, Romano JG, Sacco RL. Gardener H, et al. Among authors: asdaghi n. J Stroke Cerebrovasc Dis. 2021 Mar;30(3):105586. doi: 10.1016/j.jstrokecerebrovasdis.2020.105586. Epub 2021 Jan 5. J Stroke Cerebrovasc Dis. 2021. PMID: 33412397 Free PMC article.
CONCLUSIONS: Acute stroke care measures, particularly antithrombotic use and statin therapy, were associated with reduced odds of long-term mortality. The benefits of these acute care measures were less likely among Hispanic patients. ...
CONCLUSIONS: Acute stroke care measures, particularly antithrombotic use and statin therapy, were associated with reduced odds of long-te …
Dual antiplatelet therapy in acute ischemic stroke.
Asdaghi N, Romano JG. Asdaghi N, et al. Curr Atheroscler Rep. 2015 Jul;17(7):37. doi: 10.1007/s11883-015-0515-8. Curr Atheroscler Rep. 2015. PMID: 25990661 Review.
Randomized controlled trials and meta-analyses suggest that short-term use of dual antiplatelet treatment initiated early after ischemic stroke and TIA reduces the risk of recurrent stroke and major vascular events without significantly increasing the hemorrhagic complicat …
Randomized controlled trials and meta-analyses suggest that short-term use of dual antiplatelet treatment initiated early after ische …
Clinical correlates of infarct shape and volume in lacunar strokes: the Secondary Prevention of Small Subcortical Strokes trial.
Asdaghi N, Pearce LA, Nakajima M, Field TS, Bazan C, Cermeno F, McClure LA, Anderson DC, Hart RG, Benavente OR; SPS3 Investigators. Asdaghi N, et al. Stroke. 2014 Oct;45(10):2952-8. doi: 10.1161/STROKEAHA.114.005211. Epub 2014 Sep 4. Stroke. 2014. PMID: 25190442 Free PMC article. Clinical Trial.
CONCLUSIONS: In patients with recent lacunar stroke, vascular risk factor profile was similar among the different infarct shapes and sizes. Infarct size correlated with worse short-term functional outcome. Neither shape nor volume was predictive of stroke recurrence. ...
CONCLUSIONS: In patients with recent lacunar stroke, vascular risk factor profile was similar among the different infarct shapes and sizes. …
Therapeutic management of acute intracerebral haemorrhage.
Asdaghi N, Manawadu D, Butcher K. Asdaghi N, et al. Expert Opin Pharmacother. 2007 Dec;8(18):3097-116. doi: 10.1517/14656566.8.18.3097. Expert Opin Pharmacother. 2007. PMID: 18035956 Review.
Intracerebral haemorrhage (ICH) is a stroke resulting from spontaneous rupture of an intracranial vessel and is associated with high early mortality and long-term morbidity rates. With the exception of dedicated stroke units or neurocritical care, no surgical or medical in …
Intracerebral haemorrhage (ICH) is a stroke resulting from spontaneous rupture of an intracranial vessel and is associated with high early m …