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Alternating 17β-Estradiol and Aromatase Inhibitor Therapies Is Efficacious in Postmenopausal Women with Advanced Endocrine-Resistant ER+ Breast Cancer.
Schwartz GN, Kaufman PA, Giridhar KV, Marotti JD, Chamberlin MD, Arrick BA, Makari-Judson G, Goetz MP, Soucy SM, Kolling F, Demidenko E, Miller TW. Schwartz GN, et al. Among authors: arrick ba. Clin Cancer Res. 2023 Aug 1;29(15):2767-2773. doi: 10.1158/1078-0432.CCR-23-0112. Clin Cancer Res. 2023. PMID: 37260292 Free PMC article.
Preclinical data suggest that cycling treatment with 17beta-estradiol followed by estrogen deprivation can control tumor growth long-term. PATIENTS AND METHODS: Postmenopausal women with advanced ER+/HER2- breast cancer with recurrence or progression on 1 antiestrogen or a …
Preclinical data suggest that cycling treatment with 17beta-estradiol followed by estrogen deprivation can control tumor growth long-term …