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Hepatic galectin-3 is associated with lipid droplet area in non-alcoholic steatohepatitis in a new swine model.
Herrera-Marcos LV, Martínez-Beamonte R, Macías-Herranz M, Arnal C, Barranquero C, Puente-Lanzarote JJ, Gascón S, Herrero-Continente T, Gonzalo-Romeo G, Alastrué-Vera V, Gutiérrez-Blázquez D, Lou-Bonafonte JM, Surra JC, Rodríguez-Yoldi MJ, García-Gil A, Güemes A, Osada J. Herrera-Marcos LV, et al. Among authors: arnal c. Sci Rep. 2022 Jan 19;12(1):1024. doi: 10.1038/s41598-022-04971-z. Sci Rep. 2022. PMID: 35046474 Free PMC article.
To date, all swine-based settings have been carried out using rare predisposed breeds or long-term experiments. Herein, we fully describe a new experimental swine model for initial and reversible NASH using cross-bred animals fed on a high saturated fat, fructose, choleste …
To date, all swine-based settings have been carried out using rare predisposed breeds or long-term experiments. Herein, we fully desc …
Dietary Erythrodiol Modifies Hepatic Transcriptome in Mice in a Sex and Dose-Dependent Way.
Abuobeid R, Herrera-Marcos L, Navarro MA, Arnal C, Martínez-Beamonte R, Surra J, Osada J. Abuobeid R, et al. Among authors: arnal c. Int J Mol Sci. 2020 Oct 4;21(19):7331. doi: 10.3390/ijms21197331. Int J Mol Sci. 2020. PMID: 33020388 Free PMC article.
Erythrodiol is a terpenic compound found in a large number of plants. To test the hypotheses that its long-term administration may influence hepatic transcriptome and this could be influenced by the presence of APOA1-containing high-density lipoproteins (HDL), Western diet …
Erythrodiol is a terpenic compound found in a large number of plants. To test the hypotheses that its long-term administration may in …
Long-Term Outcomes Among Participants in the WEGENT Trial of Remission-Maintenance Therapy for Granulomatosis With Polyangiitis (Wegener's) or Microscopic Polyangiitis.
Puéchal X, Pagnoux C, Perrodeau É, Hamidou M, Boffa JJ, Kyndt X, Lifermann F, Papo T, Merrien D, Smail A, Delaval P, Hanrotel-Saliou C, Imbert B, Khouatra C, Lambert M, Leské C, Ly KH, Pertuiset E, Roblot P, Ruivard M, Subra JF, Viallard JF, Terrier B, Cohen P, Mouthon L, Le Jeunne C, Ravaud P, Guillevin L; French Vasculitis Study Group. Puéchal X, et al. Arthritis Rheumatol. 2016 Mar;68(3):690-701. doi: 10.1002/art.39450. Arthritis Rheumatol. 2016. PMID: 26473755 Free article. Clinical Trial.
OBJECTIVE: Findings from the WEGENT trial and other short-term studies have suggested that azathioprine (AZA) or methotrexate (MTX) could effectively maintain remission of granulomatosis with polyangiitis (Wegener's) (GPA) or microscopic polyangiitis (MPA). This study was …
OBJECTIVE: Findings from the WEGENT trial and other short-term studies have suggested that azathioprine (AZA) or methotrexate (MTX) c …
Dietary oleanolic acid mediates circadian clock gene expression in liver independently of diet and animal model but requires apolipoprotein A1.
Gabás-Rivera C, Martínez-Beamonte R, Ríos JL, Navarro MA, Surra JC, Arnal C, Rodríguez-Yoldi MJ, Osada J. Gabás-Rivera C, et al. Among authors: arnal c. J Nutr Biochem. 2013 Dec;24(12):2100-9. doi: 10.1016/j.jnutbio.2013.07.010. J Nutr Biochem. 2013. PMID: 24231102
Oleanolic acid is a triterpene widely distributed throughout the plant kingdom and present in virgin olive oil at a concentration of 57 mg/kg. To test the hypotheses that its long-term administration could modify hepatic gene expression in several animal models and that th …
Oleanolic acid is a triterpene widely distributed throughout the plant kingdom and present in virgin olive oil at a concentration of 57 mg/k …
Long-term follow-up of a randomized trial on 118 patients with polyarteritis nodosa or microscopic polyangiitis without poor-prognosis factors.
Samson M, Puéchal X, Devilliers H, Ribi C, Cohen P, Bienvenu B, Ruivard M, Terrier B, Pagnoux C, Mouthon L, Guillevin L; French Vasculitis Study Group (FVSG). Samson M, et al. Autoimmun Rev. 2014 Feb;13(2):197-205. doi: 10.1016/j.autrev.2013.10.001. Epub 2013 Oct 23. Autoimmun Rev. 2014. PMID: 24161361
The purpose of this study was to assess the long-term outcomes of patients with polyarteritis nodosa (PAN) or microscopic polyangiitis (MPA) without Five-Factor Score (FFS)-defined poor-prognosis factors (FFS=0) and enrolled in a prospective clinical trial. Patients were f …
The purpose of this study was to assess the long-term outcomes of patients with polyarteritis nodosa (PAN) or microscopic polyangiiti …
Microarray analysis of hepatic genes differentially expressed in the presence of the unsaponifiable fraction of olive oil in apolipoprotein E-deficient mice.
Acín S, Navarro MA, Perona JS, Surra JC, Guillen N, Arnal C, Sarría AJ, Arbonés-Mainar JM, Carnicer R, Ruiz-Gutiérrez V, Osada J. Acín S, et al. Among authors: arnal c. Br J Nutr. 2007 Apr;97(4):628-38. doi: 10.1017/S0007114507657912. Br J Nutr. 2007. PMID: 17349074
The results highlight the important biological effects of the unsaponifiable fraction of olive oil. The term 'monounsaturated fatty acid-enriched oil' no longer appears appropriate for describing all the oils to which it is currently applied since it does not adequately re …
The results highlight the important biological effects of the unsaponifiable fraction of olive oil. The term 'monounsaturated fatty a …
Response of ApoA-IV in pigs to long-term increased dietary oil intake and to the degree of unsaturation of the fatty acids.
Navarro MA, Acín S, Carnicer R, Guzmán-García MA, Arbonés-Mainar JM, Surra JC, Cebrián JA, Arnal C, Isabel B, López-Bote CJ, Osada J. Navarro MA, et al. Among authors: arnal c. Br J Nutr. 2004 Nov;92(5):763-9. doi: 10.1079/bjn20041266. Br J Nutr. 2004. PMID: 15533264
To investigate the effects of the quantity and the degree of saturation of dietary lipid on the long-term response of this Apo, and on the hypothetical coordinated regulation of the cluster in vivo, pigs were fed isoenergetic, cholesterol-free, low-lipid or lipid-enriched …
To investigate the effects of the quantity and the degree of saturation of dietary lipid on the long-term response of this Apo, and o …
Nocardia infection of a joint prosthesis complicating systemic lupus erythematosus.
Arnal C, Man H, Delisle F, M'Bappe P, Cocheton JJ. Arnal C, et al. Lupus. 2000;9(4):304-6. doi: 10.1191/096120300680198917. Lupus. 2000. PMID: 10866103
The authors report the case of a 43-year-old woman suffering from severe systemic lupus erythematosus treated with long-term prednisone, who developed Nocardia nova infection on a hip prosthesis. ...
The authors report the case of a 43-year-old woman suffering from severe systemic lupus erythematosus treated with long-term predniso …