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Chromosome level genome assembly of the Etruscan shrew Suncus etruscus.
Bukhman YV, Meyer S, Chu LF, Abueg L, Antosiewicz-Bourget J, Balacco J, Brecht M, Dinatale E, Fedrigo O, Formenti G, Fungtammasan A, Giri SJ, Hiller M, Howe K, Kihara D, Mamott D, Mountcastle J, Pelan S, Rabbani K, Sims Y, Tracey A, Wood JMD, Jarvis ED, Thomson JA, Chaisson MJP, Stewart R. Bukhman YV, et al. Among authors: antosiewicz bourget j. Sci Data. 2024 Feb 7;11(1):176. doi: 10.1038/s41597-024-03011-x. Sci Data. 2024. PMID: 38326333 Free PMC article.
The NCBI genome annotation pipeline identified 39,091 genes, 19,819 of them protein-coding. We also identified segmental duplications, inferred GO term annotations, and computed orthologs of human and mouse genes. ...
The NCBI genome annotation pipeline identified 39,091 genes, 19,819 of them protein-coding. We also identified segmental duplications, infer …
NANOG is a direct target of TGFbeta/activin-mediated SMAD signaling in human ESCs.
Xu RH, Sampsell-Barron TL, Gu F, Root S, Peck RM, Pan G, Yu J, Antosiewicz-Bourget J, Tian S, Stewart R, Thomson JA. Xu RH, et al. Among authors: antosiewicz bourget j. Cell Stem Cell. 2008 Aug 7;3(2):196-206. doi: 10.1016/j.stem.2008.07.001. Cell Stem Cell. 2008. PMID: 18682241 Free PMC article.
Using a defined medium, we show here that both TGFbeta and FGF signals synergize to inhibit BMP signaling; sustain expression of pluripotency-associated genes such as NANOG, OCT4, and SOX2; and promote long-term undifferentiated proliferation of human ESCs. We also show th …
Using a defined medium, we show here that both TGFbeta and FGF signals synergize to inhibit BMP signaling; sustain expression of pluripotenc …