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Page 1
Evaluating revefenacin as a therapeutic option for chronic obstructive pulmonary disease.
Antoniu SA, Rajnoveanu R, Ulmeanu R, Mihaltan F, Grigore M. Antoniu SA, et al. Expert Opin Pharmacother. 2020 Jun;21(9):997-1004. doi: 10.1080/14656566.2020.1745185. Epub 2020 Apr 1. Expert Opin Pharmacother. 2020. PMID: 32237914
In phase II and III clinical studies discussed in this review, revefenacin demonstrated its rapid onset of action and sustained effect on lung function on both a short- and long-term basis. EXPERT OPINION: Nebulized revefenacin with once daily use does not require any part …
In phase II and III clinical studies discussed in this review, revefenacin demonstrated its rapid onset of action and sustained effect on lu …
Triple fixed inhaled therapy in frequent chronic obstructive pulmonary disease exacerbators: potential advantages for various degrees of airways obstruction.
Antohe I, Antoniu SA, Gavrilovici C. Antohe I, et al. Among authors: antoniu sa. Expert Opin Pharmacother. 2018 Feb;19(3):287-289. doi: 10.1080/14656566.2017.1419186. Epub 2017 Dec 22. Expert Opin Pharmacother. 2018. PMID: 29271268
Expert opinion: The results discussed in this paper support the use of this combination in advanced COPD but also in earlier stages in patients with frequent exacerbation. However further and more long-term assessments are required....
Expert opinion: The results discussed in this paper support the use of this combination in advanced COPD but also in earlier stages in patie …
Efficacy of budesonide in collagenous colitis Evaluation of: Miehlke S, Madisch A, Kupcinskas L, et al. Budesonide is more effective than mesalamine or placebo in short-term treatment of collagenous colitis. Gastroenterology 2014;146(5):1222-1230 e1222.
Drug VL, Antoniu SA. Drug VL, et al. Among authors: antoniu sa. Expert Opin Pharmacother. 2014 Oct;15(15):2277-9. doi: 10.1517/14656566.2014.955468. Epub 2014 Aug 28. Expert Opin Pharmacother. 2014. PMID: 25164577
Evaluation of inhaled tiotropium in asthma, uncontrolled with standard combination therapy.
Antoniu SA, Antohe I. Antoniu SA, et al. Expert Opin Pharmacother. 2013 May;14(7):967-9. doi: 10.1517/14656566.2013.783015. Epub 2013 Mar 21. Expert Opin Pharmacother. 2013. PMID: 23514606 Review.
Tiotropium is currently under evaluation as a potential such therapy. AREAS COVERED: The long-term efficacy and safety of tiotropium was recently evaluated in two studies in patients with poorly controlled asthma under inhaled corticosteroids + long-acting beta2 agonists. …
Tiotropium is currently under evaluation as a potential such therapy. AREAS COVERED: The long-term efficacy and safety of tiotropium …
Varenicline for smoking cessation intervention in chronic obstructive pulmonary disease.
Antoniu SA, Trofor AC. Antoniu SA, et al. Expert Opin Pharmacother. 2011 Nov;12(16):2595-7. doi: 10.1517/14656566.2011.605786. Epub 2011 Aug 6. Expert Opin Pharmacother. 2011. PMID: 21819275
EXPERT OPINION: Varenicline can be an appropriate aid to maintaining smoking abstinence in patients with COPD and heavier nicotine addiction, and the documentation of the long-term effects of a smoking cessation intervention that includes this pharmacologic therapeutic age …
EXPERT OPINION: Varenicline can be an appropriate aid to maintaining smoking abstinence in patients with COPD and heavier nicotine addiction …
Inhaled gentamicin in non-cystic fibrosis bronchiectasis: effects of long-term therapy.
Antoniu SA, Trofor AC. Antoniu SA, et al. Expert Opin Pharmacother. 2011 May;12(7):1191-4. doi: 10.1517/14656566.2011.563735. Epub 2011 Apr 7. Expert Opin Pharmacother. 2011. PMID: 21470074
Previous studies demonstrated that inhaled gentamicin can reduce bacterial load and local infection in both cystic fibrosis and non-CF bronchiectasis. The study discussed in this paper demonstrates that long-term therapy with inhaled gentamicin can eradicate the infection …
Previous studies demonstrated that inhaled gentamicin can reduce bacterial load and local infection in both cystic fibrosis and non-CF bronc …
Pitrakinra for asthma.
Antoniu SA, Cojocaru I. Antoniu SA, et al. Expert Opin Biol Ther. 2010 Nov;10(11):1609-15. doi: 10.1517/14712598.2010.524203. Epub 2010 Oct 5. Expert Opin Biol Ther. 2010. PMID: 20923253 Review.
WHAT THE READER WILL GAIN: Inhaled pitrakinra demonstrated a good anti-inflammatory potential and a good safety profile on a short-term basis but its place in asthma therapy is still to be found. ...
WHAT THE READER WILL GAIN: Inhaled pitrakinra demonstrated a good anti-inflammatory potential and a good safety profile on a short-term …
Tiotropium therapy and mortality risk in COPD patients: the most severe, the most protected? Evaluation of Celli B, Decramer M, Kesten S, et al. Mortality in the 4-year trial of tiotropium (UPLIFT) in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2009; 180(10): 948-55.
Sampablo I, Carone M, Antoniu SA. Sampablo I, et al. Among authors: antoniu sa. Expert Opin Pharmacother. 2010 Jun;11(8):1439-41. doi: 10.1517/14656561003745916. Expert Opin Pharmacother. 2010. PMID: 20446856
AREAS COVERED IN THIS REVIEW: The results of the UPLIFT (Understanding Potential Long-Term Impacts on Function with Tiotropium) study evaluating the effects of 4 year therapy with tiotropium on above mentioned outcomes including mortality. WHAT THE READER WILL GAIN: Tiotro …
AREAS COVERED IN THIS REVIEW: The results of the UPLIFT (Understanding Potential Long-Term Impacts on Function with Tiotropium) study …
Effects of inhaled therapies on health-related quality of life in stable chronic obstructive pulmonary disease.
Antoniu SA. Antoniu SA. Expert Rev Pharmacoecon Outcomes Res. 2010 Apr;10(2):155-62. doi: 10.1586/erp.10.11. Expert Rev Pharmacoecon Outcomes Res. 2010. PMID: 20384562 Review.
This can be achieved, among other measures, with inhaled therapies, which, in this disease, are used alone or combined in a step-up approach based on disease severity. As COPD is a chronic disease, the long-term effects of inhaled therapies on various disease outcome measu …
This can be achieved, among other measures, with inhaled therapies, which, in this disease, are used alone or combined in a step-up approach …
MEDI-528, an anti-IL-9 humanized antibody for the treatment of asthma.
Antoniu SA. Antoniu SA. Curr Opin Mol Ther. 2010 Apr;12(2):233-9. Curr Opin Mol Ther. 2010. PMID: 20373267
To date, clinical data are modest, although insufficient to judge the efficacy of the drug in humans, and larger and longer-term clinical trials are required. MEDI-528, along with other anticytokine therapies targeting different ILs, remains under investigation in early-ph …
To date, clinical data are modest, although insufficient to judge the efficacy of the drug in humans, and larger and longer-term clin …
21 results