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Berberine Directly Affects the Gut Microbiota to Promote Intestinal Farnesoid X Receptor Activation.
Tian Y, Cai J, Gui W, Nichols RG, Koo I, Zhang J, Anitha M, Patterson AD. Tian Y, et al. Among authors: anitha m. Drug Metab Dispos. 2019 Feb;47(2):86-93. doi: 10.1124/dmd.118.083691. Epub 2018 Nov 8. Drug Metab Dispos. 2019. PMID: 30409838 Free PMC article.
In vivo, the metabolomic response and changes in mouse intestinal bacterial communities treated with BBR (100 mg/kg) for 5 days were assessed using NMR- and mass spectrometry-based metabolomics coupled with multivariate data analysis. Short-term BBR exposure altered intest …
In vivo, the metabolomic response and changes in mouse intestinal bacterial communities treated with BBR (100 mg/kg) for 5 days were assesse …
Availability and affordability of blood pressure-lowering medicines and the effect on blood pressure control in high-income, middle-income, and low-income countries: an analysis of the PURE study data.
Attaei MW, Khatib R, McKee M, Lear S, Dagenais G, Igumbor EU, AlHabib KF, Kaur M, Kruger L, Teo K, Lanas F, Yusoff K, Oguz A, Gupta R, Yusufali AM, Bahonar A, Kutty R, Rosengren A, Mohan V, Avezum A, Yusuf R, Szuba A, Rangarajan S, Chow C, Yusuf S; PURE study investigators. Attaei MW, et al. Lancet Public Health. 2017 Sep;2(9):e411-e419. doi: 10.1016/S2468-2667(17)30141-X. Epub 2017 Sep 5. Lancet Public Health. 2017. PMID: 29253412 Free article.
FUNDING: Population Health Research Institute, the Canadian Institutes of Health Research, Heart and Stroke Foundation of Ontario, Canadian Institutes of Health Research Strategy for Patient Oriented Research through the Ontario SPOR Support Unit, the Ontario Ministry of Health a …
FUNDING: Population Health Research Institute, the Canadian Institutes of Health Research, Heart and Stroke Foundation of Ontario, Canadian …
Use of secondary prevention drugs for cardiovascular disease in the community in high-income, middle-income, and low-income countries (the PURE Study): a prospective epidemiological survey.
Yusuf S, Islam S, Chow CK, Rangarajan S, Dagenais G, Diaz R, Gupta R, Kelishadi R, Iqbal R, Avezum A, Kruger A, Kutty R, Lanas F, Lisheng L, Wei L, Lopez-Jaramillo P, Oguz A, Rahman O, Swidan H, Yusoff K, Zatonski W, Rosengren A, Teo KK; Prospective Urban Rural Epidemiology (PURE) Study Investigators. Yusuf S, et al. Lancet. 2011 Oct 1;378(9798):1231-43. doi: 10.1016/S0140-6736(11)61215-4. Epub 2011 Aug 26. Lancet. 2011. PMID: 21872920
INTERPRETATION: Because use of secondary prevention medications is low worldwide-especially in low-income countries and rural areas-systematic approaches are needed to improve the long-term use of basic, inexpensive, and effective drugs. FUNDING: Full funding sources liste …
INTERPRETATION: Because use of secondary prevention medications is low worldwide-especially in low-income countries and rural areas-systemat …