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The trajectory of very old critically ill patients.
Guidet B, Vallet H, Flaatten H, Joynt G, Bagshaw SM, Leaver SK, Beil M, Du B, Forte DN, Angus DC, Sviri S, de Lange D, Herridge MS, Jung C. Guidet B, et al. Among authors: angus dc. Intensive Care Med. 2024 Feb;50(2):181-194. doi: 10.1007/s00134-023-07298-z. Epub 2024 Jan 18. Intensive Care Med. 2024. PMID: 38236292 Review.
This new integrative approach mobilises expertise at each step of the process beginning prior to intensive care unit (ICU) admission and extending to long-term follow-up. In this review, several international experts have contributed to provide recommendations that can be …
This new integrative approach mobilises expertise at each step of the process beginning prior to intensive care unit (ICU) admission and ext …
Long-term (180-Day) Outcomes in Critically Ill Patients With COVID-19 in the REMAP-CAP Randomized Clinical Trial.
Writing Committee for the REMAP-CAP Investigators; Higgins AM, Berry LR, Lorenzi E, Murthy S, McQuilten Z, Mouncey PR, Al-Beidh F, Annane D, Arabi YM, Beane A, van Bentum-Puijk W, Bhimani Z, Bonten MJM, Bradbury CA, Brunkhorst FM, Burrell A, Buzgau A, Buxton M, Charles WN, Cove M, Detry MA, Estcourt LJ, Fagbodun EO, Fitzgerald M, Girard TD, Goligher EC, Goossens H, Haniffa R, Hills T, Horvat CM, Huang DT, Ichihara N, Lamontagne F, Marshall JC, McAuley DF, McGlothlin A, McGuinness SP, McVerry BJ, Neal MD, Nichol AD, Parke RL, Parker JC, Parry-Billings K, Peters SEC, Reyes LF, Rowan KM, Saito H, Santos MS, Saunders CT, Serpa-Neto A, Seymour CW, Shankar-Hari M, Stronach LM, Turgeon AF, Turner AM, van de Veerdonk FL, Zarychanski R, Green C, Lewis RJ, Angus DC, McArthur CJ, Berry S, Derde LPG, Gordon AC, Webb SA, Lawler PR. Writing Committee for the REMAP-CAP Investigators, et al. Among authors: angus dc. JAMA. 2023 Jan 3;329(1):39-51. doi: 10.1001/jama.2022.23257. JAMA. 2023. PMID: 36525245 Free PMC article.
IMPORTANCE: The longer-term effects of therapies for the treatment of critically ill patients with COVID-19 are unknown. OBJECTIVE: To determine the effect of multiple interventions for critically ill adults with COVID-19 on longer-term outcomes. DESIGN, SETTING, AN …
IMPORTANCE: The longer-term effects of therapies for the treatment of critically ill patients with COVID-19 are unknown. OBJECTIVE: T …
The Association of Baseline Plasma SARS-CoV-2 Nucleocapsid Antigen Level and Outcomes in Patients Hospitalized With COVID-19.
ACTIV-3/TICO Study Group; Rogers AJ, Wentworth D, Phillips A, Shaw-Saliba K, Dewar RL, Aggarwal NR, Babiker AG, Chang W, Dharan NJ, Davey VJ, Higgs ES, Gerry N, Ginde AA, Hayanga JWA, Highbarger H, Highbarger JL, Jain MK, Kan V, Kim K, Lallemand P, Leshnower BG, Lutaakome JK, Matthews G, Mourad A, Mylonakis E, Natarajan V, Padilla ML, Pandit LM, Paredes R, Pett S, Ramachandruni S, Rehman MT, Sherman BT, Files DC, Brown SM, Matthay MA, Thompson BT, Neaton JD, Lane HC, Lundgren JD. ACTIV-3/TICO Study Group, et al. Ann Intern Med. 2022 Oct;175(10):1401-1410. doi: 10.7326/M22-0924. Epub 2022 Aug 30. Ann Intern Med. 2022. PMID: 36037469 Free PMC article.
OBJECTIVE: To evaluate whether levels of plasma antigen can predict short-term clinical outcomes and identify clinical and viral factors associated with plasma antigen levels in hospitalized patients with SARS-CoV-2. ...
OBJECTIVE: To evaluate whether levels of plasma antigen can predict short-term clinical outcomes and identify clinical and viral fact …
Comparison of the prognostic performance of the CURB-65 and a modified version of the pneumonia severity index designed to identify high-risk patients using the International Community-Acquired Pneumonia Collaboration Cohort.
Barlas RS, Clark AB, Loke YK, Kwok CS, Angus DC, Uranga A, España PP, Eurich DT, Huang DT, Man SY, Rainer TH, Yealy DM, Myint PK, Mor MK, Fine MJ. Barlas RS, et al. Among authors: angus dc. Respir Med. 2022 Aug-Sep;200:106884. doi: 10.1016/j.rmed.2022.106884. Epub 2022 Jun 13. Respir Med. 2022. PMID: 35767924
We compared the prognostic performance of a modified version of the PSI designed to identify high-risk patients (i.e., PSI-HR) to CURB-65 in predicting short-term mortality. METHODS: Using data from 6 pneumonia cohorts, we designed PSI-HR as a 6-class prediction rule using …
We compared the prognostic performance of a modified version of the PSI designed to identify high-risk patients (i.e., PSI-HR) to CURB-65 in …
"I Didn't Want My Baby to Pass, But I Didn't Want Him Suffering Either": Comparing Bereaved Parents' Narratives With Nursing End-of-Life Assessments in the Pediatric Intensive Care Unit.
Broden EG, Hinds PS, Werner-Lin AV, Curley MAQ; for the RESTORE Study Investigators. Broden EG, et al. J Hosp Palliat Nurs. 2022 Oct 1;24(5):271-280. doi: 10.1097/NJH.0000000000000884. Epub 2022 Jun 6. J Hosp Palliat Nurs. 2022. PMID: 35666188 Free PMC article.
Little is known about how nursing care at the end of a child's life impacts long-term parental bereavement. We aimed to explain, contextualize, and examine comparisons between quantitative trends in children's end-of-life care and parents' qualitative perceptions. ...
Little is known about how nursing care at the end of a child's life impacts long-term parental bereavement. We aimed to explain, cont …
Association of Acute Respiratory Failure in Early Childhood With Long-term Neurocognitive Outcomes.
Watson RS, Beers SR, Asaro LA, Burns C, Koh MJ, Perry MA, Angus DC, Wypij D, Curley MAQ; RESTORE-Cognition Investigators. Watson RS, et al. Among authors: angus dc. JAMA. 2022 Mar 1;327(9):836-845. doi: 10.1001/jama.2022.1480. JAMA. 2022. PMID: 35230393 Free PMC article.
IMPORTANCE: Approximately 23 700 US children undergo invasive mechanical ventilation for acute respiratory failure annually, with unknown long-term effects on neurocognitive function. OBJECTIVE: To evaluate neurocognitive outcomes of children who survive pediatric intensiv …
IMPORTANCE: Approximately 23 700 US children undergo invasive mechanical ventilation for acute respiratory failure annually, with unknown lo …
Recall of clinical trial participation and attrition rates in survivors of acute respiratory distress syndrome.
Carlton EF, Ice E, Barbaro RP, Kampuis L, Moss M, Angus DC, Banner-Goodspeed VM, Ginde AA, Gong MN, Grissom CK, Hou PC, Huang DT, Hough CTL, Talmor DS, Thompson BT, Yealy DM, Couper MP, Iwashyna TJ; NHLBI Prevention and Early Treatment of Acute Lung Injury (PETAL) Network. Carlton EF, et al. Among authors: angus dc. J Crit Care. 2021 Aug;64:160-164. doi: 10.1016/j.jcrc.2021.04.006. Epub 2021 Apr 17. J Crit Care. 2021. PMID: 33906105 Free PMC article.
MATERIALS/METHODS: In this ancillary study of the Re-evaluation of Systemic Early neuromuscular blockade(ROSE) trial, we measured the rate of study participation recall 3 months following discharge and subsequent study attrition at 6 months. We compared patient and hospital chara …
MATERIALS/METHODS: In this ancillary study of the Re-evaluation of Systemic Early neuromuscular blockade(ROSE) trial, we measured the rate o …
US Hospital Capacity Managers' Experiences and Concerns Regarding Preparedness for Seasonal Influenza and Influenza-like Illness.
Harris GH, Rak KJ, Kahn JM, Angus DC, Mancing OR, Driessen J, Wallace DJ. Harris GH, et al. Among authors: angus dc. JAMA Netw Open. 2021 Mar 1;4(3):e212382. doi: 10.1001/jamanetworkopen.2021.2382. JAMA Netw Open. 2021. PMID: 33739431 Free PMC article.
DESIGN, SETTING, AND PARTICIPANTS: In this qualitative study, semistructured telephone interviews were conducted between April 2018 and January 2019 with a random sample of capacity management administrators responsible for throughput and hospital capacity at short-term, a …
DESIGN, SETTING, AND PARTICIPANTS: In this qualitative study, semistructured telephone interviews were conducted between April 2018 and Janu …
Dichloroacetate-induced metabolic reprogramming improves lifespan in a Drosophila model of surviving sepsis.
Bakalov V, Reyes-Uribe L, Deshpande R, Maloy AL, Shapiro SD, Angus DC, Chang CH, Le Moyec L, Wendell SG, Kaynar AM. Bakalov V, et al. Among authors: angus dc. PLoS One. 2020 Nov 5;15(11):e0241122. doi: 10.1371/journal.pone.0241122. eCollection 2020. PLoS One. 2020. PMID: 33151963 Free PMC article.
Sepsis is the leading cause of death in hospitalized patients and beyond the hospital stay and these long-term sequelae are due in part to unresolved inflammation. Metabolic shift from oxidative phosphorylation to aerobic glycolysis links metabolism to inflammation and suc …
Sepsis is the leading cause of death in hospitalized patients and beyond the hospital stay and these long-term sequelae are due in pa …
77 results