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Long-term neurological symptoms after acute COVID-19 illness requiring hospitalization in adult patients: insights from the ISARIC-COVID-19 follow-up study.
Battaglini D, White NM, Premraj L, Wanjiru Citarella B, Merson L, Robba C, Thomson D, Cho SM; ISARIC Clinical Characterization Group. Battaglini D, et al. J Neurol. 2024 Jan;271(1):79-86. doi: 10.1007/s00415-023-12133-y. Epub 2023 Dec 6. J Neurol. 2024. PMID: 38055020 Free PMC article. No abstract available.
Immunoglobulin, glucocorticoid, or combination therapy for multisystem inflammatory syndrome in children: a propensity-weighted cohort study.
Channon-Wells S, Vito O, McArdle AJ, Seaby EG, Patel H, Shah P, Pazukhina E, Wilson C, Broderick C, D'Souza G, Keren I, Nijman RG, Tremoulet A, Munblit D, Ulloa-Gutierrez R, Carter MJ, Ramnarayan P, De T, Hoggart C, Whittaker E, Herberg JA, Kaforou M, Cunnington AJ, Blyuss O, Levin M; Best Available Treatment Study (BATS) consortium. Channon-Wells S, et al. Lancet Rheumatol. 2023 Apr;5(4):e184-e199. doi: 10.1016/S2665-9913(23)00029-2. Epub 2023 Feb 14. Lancet Rheumatol. 2023. PMID: 36855438 Free PMC article.
Long-term kidney function recovery and mortality after COVID-19-associated acute kidney injury: An international multi-centre observational cohort study.
Tan BWL, Tan BWQ, Tan ALM, Schriver ER, Gutiérrez-Sacristán A, Das P, Yuan W, Hutch MR, García Barrio N, Pedrera Jimenez M, Abu-El-Rub N, Morris M, Moal B, Verdy G, Cho K, Ho YL, Patel LP, Dagliati A, Neuraz A, Klann JG, South AM, Visweswaran S, Hanauer DA, Maidlow SE, Liu M, Mowery DL, Batugo A, Makoudjou A, Tippmann P, Zöller D, Brat GA, Luo Y, Avillach P, Bellazzi R, Chiovato L, Malovini A, Tibollo V, Samayamuthu MJ, Serrano Balazote P, Xia Z, Loh NHW, Chiudinelli L, Bonzel CL, Hong C, Zhang HG, Weber GM, Kohane IS, Cai T, Omenn GS, Holmes JH, Ngiam KY; Consortium for Clinical Characterization of COVID-19 by EHR (4CE). Tan BWL, et al. EClinicalMedicine. 2022 Nov 7;55:101724. doi: 10.1016/j.eclinm.2022.101724. eCollection 2023 Jan. EClinicalMedicine. 2022. PMID: 36381999 Free PMC article.
INTERPRETATION: COVID-19-associated AKI was associated with higher mortality, and severe COVID-19-associated AKI was associated with worse long-term post-AKI kidney function recovery. FUNDING: Authors are supported by various funders, with full details stated in the acknow …
INTERPRETATION: COVID-19-associated AKI was associated with higher mortality, and severe COVID-19-associated AKI was associated with worse l …
Potent human broadly SARS-CoV-2-neutralizing IgA and IgG antibodies effective against Omicron BA.1 and BA.2.
Planchais C, Fernández I, Bruel T, de Melo GD, Prot M, Beretta M, Guardado-Calvo P, Dufloo J, Molinos-Albert LM, Backovic M, Chiaravalli J, Giraud E, Vesin B, Conquet L, Grzelak L, Planas D, Staropoli I, Guivel-Benhassine F, Hieu T, Boullé M, Cervantes-Gonzalez M, Ungeheuer MN, Charneau P, van der Werf S, Agou F; French COVID Cohort Study Group; CORSER Study Group; Dimitrov JD, Simon-Lorière E, Bourhy H, Montagutelli X, Rey FA, Schwartz O, Mouquet H. Planchais C, et al. J Exp Med. 2022 Jul 4;219(7):e20220638. doi: 10.1084/jem.20220638. Epub 2022 Jun 15. J Exp Med. 2022. PMID: 35704748 Free PMC article.
Memory B-cell and antibody responses to the SARS-CoV-2 spike protein contribute to long-term immune protection against severe COVID-19, which can also be prevented by antibody-based interventions. ...
Memory B-cell and antibody responses to the SARS-CoV-2 spike protein contribute to long-term immune protection against severe COVID-1 …
Neuroinflammatory Disease following Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Children.
Aubart M, Roux CJ, Durrleman C, Gins C, Hully M, Kossorotoff M, Gitiaux C, Levy R, Moulin F, Debray A, Belhadjer Z, Georget E, Kom T, Blanc P, Wehbi S, Mazeghrane M, Tencer J, Gajdos V, Rouget S, De Pontual L, Basmaci R, Yacouben K, Angoulvant F, Leruez-Ville M, Sterlin D, Rozenberg F, Robert MP, Zhang SY, Boddaert N, Desguerre I. Aubart M, et al. Among authors: angoulvant f. J Pediatr. 2022 Aug;247:22-28.e2. doi: 10.1016/j.jpeds.2022.05.018. Epub 2022 May 14. J Pediatr. 2022. PMID: 35577119 Free PMC article.
Overall, 89% of patients (17/19) received anti-inflammatory treatment, primarily high-pulse methylprednisolone. All patients had a complete long-term recovery and, to date, no patient with autoantibodies presented with a relapse. ...
Overall, 89% of patients (17/19) received anti-inflammatory treatment, primarily high-pulse methylprednisolone. All patients had a complete …
Fall of Community-Acquired Pneumonia in Children following COVID-19 Non-Pharmaceutical Interventions: A Time Series Analysis.
Rybak A, Yang DD, Schrimpf C, Guedj R, Levy C, Cohen R, Gajdos V, Tort J, Skurnik D, Ouldali N, Angoulvant F. Rybak A, et al. Among authors: angoulvant f. Pathogens. 2021 Oct 24;10(11):1375. doi: 10.3390/pathogens10111375. Pathogens. 2021. PMID: 34832531 Free PMC article.
We observed a dramatic decrease of CAP in children following NPIs implementation. Further studies are required to assess the long-term impact of these measures....
We observed a dramatic decrease of CAP in children following NPIs implementation. Further studies are required to assess the long-term …
Pediatric Infectious Disease Group (GPIP) position paper on the immune debt of the COVID-19 pandemic in childhood, how can we fill the immunity gap?
Cohen R, Ashman M, Taha MK, Varon E, Angoulvant F, Levy C, Rybak A, Ouldali N, Guiso N, Grimprel E. Cohen R, et al. Among authors: angoulvant f. Infect Dis Now. 2021 Aug;51(5):418-423. doi: 10.1016/j.idnow.2021.05.004. Epub 2021 May 12. Infect Dis Now. 2021. PMID: 33991720 Free PMC article. Review.
While NPIs limited the transmission of SARS-CoV-2, they also reduced the spread of other pathogens during and after lockdown periods, despite the re-opening of schools since June 2020 in France. This positive collateral effect in the short term is welcome as it prevents ad …
While NPIs limited the transmission of SARS-CoV-2, they also reduced the spread of other pathogens during and after lockdown periods, despit …
Invasive pneumococcal disease incidence in children and adults in France during the pneumococcal conjugate vaccine era: an interrupted time-series analysis of data from a 17-year national prospective surveillance study.
Ouldali N, Varon E, Levy C, Angoulvant F, Georges S, Ploy MC, Kempf M, Cremniter J, Cohen R, Bruhl DL, Danis K. Ouldali N, et al. Among authors: angoulvant f. Lancet Infect Dis. 2021 Jan;21(1):137-147. doi: 10.1016/S1473-3099(20)30165-1. Epub 2020 Jul 20. Lancet Infect Dis. 2021. PMID: 32702302
BACKGROUND: The long-term benefits of pneumococcal conjugate vaccines (PCVs) remain unknown because of serotype replacement. ...However, a rebound in cases among children and adults since 2015, driven by several emerging non-PCV13 serotypes, jeopardises the long-term …
BACKGROUND: The long-term benefits of pneumococcal conjugate vaccines (PCVs) remain unknown because of serotype replacement. ...Howev …
Long-term Association of 13-Valent Pneumococcal Conjugate Vaccine Implementation With Rates of Community-Acquired Pneumonia in Children.
Ouldali N, Levy C, Minodier P, Morin L, Biscardi S, Aurel M, Dubos F, Dommergues MA, Mezgueldi E, Levieux K, Madhi F, Hees L, Craiu I, Gras Le Guen C, Launay E, Zenkhri F, Lorrot M, Gillet Y, Béchet S, Hau I, Martinot A, Varon E, Angoulvant F, Cohen R. Ouldali N, et al. Among authors: angoulvant f. JAMA Pediatr. 2019 Apr 1;173(4):362-370. doi: 10.1001/jamapediatrics.2018.5273. JAMA Pediatr. 2019. PMID: 30715140 Free PMC article.
IMPORTANCE: In several countries, 5 years after 13-valent pneumococcal conjugate vaccine (PCV13) implementation, serotype replacement has been reported for invasive pneumococcal disease, which raises concerns about the long-term outcome of PCV13 implementation. The long- …
IMPORTANCE: In several countries, 5 years after 13-valent pneumococcal conjugate vaccine (PCV13) implementation, serotype replacement has be …
Incidence of paediatric pneumococcal meningitis and emergence of new serotypes: a time-series analysis of a 16-year French national survey.
Ouldali N, Levy C, Varon E, Bonacorsi S, Béchet S, Cohen R, Angoulvant F; French Pediatric Meningitis Network. Ouldali N, et al. Among authors: angoulvant f. Lancet Infect Dis. 2018 Sep;18(9):983-991. doi: 10.1016/S1473-3099(18)30349-9. Epub 2018 Jul 23. Lancet Infect Dis. 2018. PMID: 30049623
BACKGROUND: Successive implementation of seven-valent then 13-valent pneumococcal conjugate vaccines (PCVs) led to a marked decrease in pneumococcal disease burden, including pneumococcal meningitis. We assessed the long-term effect of implementation of PCVs on incidence o …
BACKGROUND: Successive implementation of seven-valent then 13-valent pneumococcal conjugate vaccines (PCVs) led to a marked decrease in pneu …