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Functional Dysregulations in CA1 Hippocampal Networks of a 3-Hit Mouse Model of Schizophrenia.
Percelay S, Billard JM, Freret T, Andrieux A, Boulouard M, Bouet V. Percelay S, et al. Among authors: andrieux a. Int J Mol Sci. 2021 Mar 5;22(5):2644. doi: 10.3390/ijms22052644. Int J Mol Sci. 2021. PMID: 33807989 Free PMC article.
While basal excitatory transmission remained unaffected, NMDA receptor (NMDAr)-mediated long-term potentiation (LTP) triggered by theta-burst (TBS) but not by high-frequency (HFS) stimulation was impaired in 3-hit mice. ...
While basal excitatory transmission remained unaffected, NMDA receptor (NMDAr)-mediated long-term potentiation (LTP) triggered by the …
Pyr1-Mediated Pharmacological Inhibition of LIM Kinase Restores Synaptic Plasticity and Normal Behavior in a Mouse Model of Schizophrenia.
Gory-Fauré S, Powell R, Jonckheere J, Lanté F, Denarier E, Peris L, Nguyen CH, Buisson A, Lafanechère L, Andrieux A. Gory-Fauré S, et al. Among authors: andrieux a. Front Pharmacol. 2021 Mar 12;12:627995. doi: 10.3389/fphar.2021.627995. eCollection 2021. Front Pharmacol. 2021. PMID: 33790791 Free PMC article.
Our results show that Pyr1 can modulate MT dynamics in neurons. In MAP6 KO mice, chronic LIMK inhibition by long-term treatment with Pyr1 can restore normal dendritic spine density and also improves long-term potentiation, both of which are altered in these mice. .. …
Our results show that Pyr1 can modulate MT dynamics in neurons. In MAP6 KO mice, chronic LIMK inhibition by long-term treatment with …
Evolution of morphological but not aggressiveness-related traits following a major resistance breakdown in the poplar rust fungus, Melampsora larici-populina.
Maupetit A, Fabre B, Pétrowski J, Andrieux A, De Mita S, Frey P, Halkett F, Hayden KJ. Maupetit A, et al. Among authors: andrieux a. Evol Appl. 2020 Oct 16;14(2):513-523. doi: 10.1111/eva.13136. eCollection 2021 Feb. Evol Appl. 2020. PMID: 33664791 Free PMC article.
Hence, this study is one example suggesting that the use of qualitative resistance may be revealed to be less detrimental to long-term sustainable crop production....
Hence, this study is one example suggesting that the use of qualitative resistance may be revealed to be less detrimental to long-term …
Short- and long-term efficacy of electroconvulsive stimulation in animal models of depression: The essential role of neuronal survival.
Jonckheere J, Deloulme JC, Dall'Igna G, Chauliac N, Pelluet A, Nguon AS, Lentini C, Brocard J, Denarier E, Brugière S, Couté Y, Heinrich C, Porcher C, Holtzmann J, Andrieux A, Suaud-Chagny MF, Gory-Fauré S. Jonckheere J, et al. Among authors: andrieux a. Brain Stimul. 2018 Nov-Dec;11(6):1336-1347. doi: 10.1016/j.brs.2018.08.001. Epub 2018 Aug 15. Brain Stimul. 2018. PMID: 30146428 Free article.
CONCLUSION: Altogether, these results reveal that increased synaptic connectivity and extended neuronal survival are key to the short and long-term efficacy of ECS....
CONCLUSION: Altogether, these results reveal that increased synaptic connectivity and extended neuronal survival are key to the short and lo …
3D imaging of the brain morphology and connectivity defects in a model of psychiatric disorders: MAP6-KO mice.
Gimenez U, Boulan B, Mauconduit F, Taurel F, Leclercq M, Denarier E, Brocard J, Gory-Fauré S, Andrieux A, Lahrech H, Deloulme JC. Gimenez U, et al. Among authors: andrieux a. Sci Rep. 2017 Sep 4;7(1):10308. doi: 10.1038/s41598-017-10544-2. Sci Rep. 2017. PMID: 28871106 Free PMC article.
The large spectrum of social and cognitive impairments observed in MAP6-KO mice are reminiscent of the symptoms observed in psychiatric diseases, such as schizophrenia, and respond positively to long-term treatment with antipsychotics. MAP6-KO mice have therefore been prop …
The large spectrum of social and cognitive impairments observed in MAP6-KO mice are reminiscent of the symptoms observed in psychiatric dise …
Both chronic treatments by epothilone D and fluoxetine increase the short-term memory and differentially alter the mood status of STOP/MAP6 KO mice.
Fournet V, de Lavilléon G, Schweitzer A, Giros B, Andrieux A, Martres MP. Fournet V, et al. Among authors: andrieux a. J Neurochem. 2012 Dec;123(6):982-96. doi: 10.1111/jnc.12027. Epub 2012 Oct 25. J Neurochem. 2012. PMID: 23013328 Free article.
Interestingly, both epothilone D and fluoxetine chronic treatments improved the short-term memory of STOP KO mice. Such treatments did not affect the serotonin and norepinephrine transporter densities in cerebral areas of mice. ...
Interestingly, both epothilone D and fluoxetine chronic treatments improved the short-term memory of STOP KO mice. Such treatments di …
The deletion of STOP/MAP6 protein in mice triggers highly altered mood and impaired cognitive performances.
Fournet V, Schweitzer A, Chevarin C, Deloulme JC, Hamon M, Giros B, Andrieux A, Martres MP. Fournet V, et al. Among authors: andrieux a. J Neurochem. 2012 Apr;121(1):99-114. doi: 10.1111/j.1471-4159.2011.07615.x. Epub 2012 Jan 23. J Neurochem. 2012. PMID: 22146001 Free article.
In addition, although STOP KO mice had a preserved very short-term memory, they failed to perform well in all other learning and memory tasks. ...
In addition, although STOP KO mice had a preserved very short-term memory, they failed to perform well in all other learning and memo …
Chronic administration of atypical antipsychotics improves behavioral and synaptic defects of STOP null mice.
Delotterie D, Ruiz G, Brocard J, Schweitzer A, Roucard C, Roche Y, Suaud-Chagny MF, Bressand K, Andrieux A. Delotterie D, et al. Among authors: andrieux a. Psychopharmacology (Berl). 2010 Jan;208(1):131-41. doi: 10.1007/s00213-009-1712-3. Epub 2009 Nov 21. Psychopharmacology (Berl). 2010. PMID: 19936716 Free PMC article.
In STOP null mice, behavioral defects are associated with synaptic plasticity abnormalities including defects in long-term potentiation. In these mice, long-term administration of typical antipsychotics has been shown to partially alleviate behavioral defects but, a …
In STOP null mice, behavioral defects are associated with synaptic plasticity abnormalities including defects in long-term potentiati …
The stop null mice model for schizophrenia displays [corrected] cognitive and social deficits partly alleviated by neuroleptics.
Bégou M, Volle J, Bertrand JB, Brun P, Job D, Schweitzer A, Saoud M, D'Amato T, Andrieux A, Suaud-Chagny MF. Bégou M, et al. Among authors: andrieux a. Neuroscience. 2008 Nov 11;157(1):29-39. doi: 10.1016/j.neuroscience.2008.07.080. Epub 2008 Aug 29. Neuroscience. 2008. PMID: 18804150 Free article.
Compared with wild-type mice, STOP null mice exhibited deficits in the non-aggressive component of social recognition, short term working memory and social and spatial learning. As described in humans, learning deficits in STOP null mice were poorly sensitive to long te …
Compared with wild-type mice, STOP null mice exhibited deficits in the non-aggressive component of social recognition, short term wor …
17 results