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A longitudinal field study of commercial honey bees shows that non-native probiotics do not rescue antibiotic treatment, and are generally not beneficial.
Anderson KE, Allen NO, Copeland DC, Kortenkamp OL, Erickson R, Mott BM, Oliver R. Anderson KE, et al. Sci Rep. 2024 Jan 23;14(1):1954. doi: 10.1038/s41598-024-52118-z. Sci Rep. 2024. PMID: 38263184 Free PMC article.
A colony-level application of the antibiotics oxytetracycline and tylosin produced an immediate decrease in gut microbiome size, and over the longer-term, very different and persistent dysbiotic effects on the composition and membership of the hindgut microbiome. ...
A colony-level application of the antibiotics oxytetracycline and tylosin produced an immediate decrease in gut microbiome size, and over th …
Using Real-World Data to Inform Value-Based Contracts for Cell and Gene Therapies in Medicaid.
Zemplenyi A, Leonard J, DiStefano MJ, Anderson KE, Wright GC, Mendola ND, Nair K, McQueen RB. Zemplenyi A, et al. Among authors: anderson ke. Pharmacoeconomics. 2024 Mar;42(3):319-328. doi: 10.1007/s40273-023-01335-x. Epub 2023 Nov 21. Pharmacoeconomics. 2024. PMID: 37989969 Free PMC article.
OBJECTIVE: High upfront costs and long-term benefit uncertainties of gene therapies challenge Medicaid budgets, making value-based contracts a potential solution. ...
OBJECTIVE: High upfront costs and long-term benefit uncertainties of gene therapies challenge Medicaid budgets, making value-based co …
Acute hepatic porphyrias: Recommendations for diagnosis and management with real-world examples.
Moghe A, Dickey A, Erwin A, Leaf RK, O'Brien A, Quigley JG, Thapar M, Anderson KE. Moghe A, et al. Among authors: anderson ke. Mol Genet Metab. 2023 Nov;140(3):107670. doi: 10.1016/j.ymgme.2023.107670. Epub 2023 Jul 27. Mol Genet Metab. 2023. PMID: 37542766 Free article.
Here we describe six case studies from our own real-world experience to highlight current recommendations and challenges associated with the diagnosis and long-term management of the disease....
Here we describe six case studies from our own real-world experience to highlight current recommendations and challenges associated with the …
A small-molecule PI3Kα activator for cardioprotection and neuroregeneration.
Gong GQ, Bilanges B, Allsop B, Masson GR, Roberton V, Askwith T, Oxenford S, Madsen RR, Conduit SE, Bellini D, Fitzek M, Collier M, Najam O, He Z, Wahab B, McLaughlin SH, Chan AWE, Feierberg I, Madin A, Morelli D, Bhamra A, Vinciauskaite V, Anderson KE, Surinova S, Pinotsis N, Lopez-Guadamillas E, Wilcox M, Hooper A, Patel C, Whitehead MA, Bunney TD, Stephens LR, Hawkins PT, Katan M, Yellon DM, Davidson SM, Smith DM, Phillips JB, Angell R, Williams RL, Vanhaesebroeck B. Gong GQ, et al. Among authors: anderson ke. Nature. 2023 Jun;618(7963):159-168. doi: 10.1038/s41586-023-05972-2. Epub 2023 May 24. Nature. 2023. PMID: 37225977 Free PMC article.
This study identifies a chemical tool to directly probe the PI3Kalpha signalling pathway and a new approach to modulate PI3K activity, widening the therapeutic potential of targeting these enzymes through short-term activation for tissue protection and regeneration. Our fi …
This study identifies a chemical tool to directly probe the PI3Kalpha signalling pathway and a new approach to modulate PI3K activity, widen …
Long transients and dendritic network structure affect spatial predator-prey dynamics in experimental microcosms.
Green MD, Woodie CA, Whitesell M, Anderson KE. Green MD, et al. Among authors: anderson ke. J Anim Ecol. 2023 Jul;92(7):1416-1430. doi: 10.1111/1365-2656.13943. Epub 2023 May 16. J Anim Ecol. 2023. PMID: 37194203
Few empirical studies have examined the importance of transients in spatial food webs, especially in a network context, due to the difficulty in collecting the large scale and long-term data required. We examined predator-prey dynamics in protist microcosms using three exp …
Few empirical studies have examined the importance of transients in spatial food webs, especially in a network context, due to the difficult …
Long-Term Deutetrabenazine Treatment for Tardive Dyskinesia Is Associated With Sustained Benefits and Safety: A 3-Year, Open-Label Extension Study.
Hauser RA, Barkay H, Fernandez HH, Factor SA, Jimenez-Shahed J, Gross N, Marinelli L, Wilhelm A, Alexander J, Gordon MF, Savola JM, Anderson KE. Hauser RA, et al. Among authors: anderson ke. Front Neurol. 2022 Feb 23;13:773999. doi: 10.3389/fneur.2022.773999. eCollection 2022. Front Neurol. 2022. PMID: 35280262 Free PMC article.
In two 12-week pivotal studies, deutetrabenazine demonstrated statistically significant improvements in Abnormal Involuntary Movement Scale (AIMS) scores, with favorable safety/tolerability in TD patients. This study reports long-term efficacy and safety of deutetrabenazin …
In two 12-week pivotal studies, deutetrabenazine demonstrated statistically significant improvements in Abnormal Involuntary Movement Scale …
Biochemical Diagnosis of Acute Hepatic Porphyria: Updated Expert Recommendations for Primary Care Physicians.
Anderson KE, Lobo R, Salazar D, Schloetter M, Spitzer G, White AL, Young RM, Bonkovsky HL, Frank EL, Mora J, Tortorelli S. Anderson KE, et al. Am J Med Sci. 2021 Aug;362(2):113-121. doi: 10.1016/j.amjms.2021.03.004. Epub 2021 Apr 16. Am J Med Sci. 2021. PMID: 33865828 Free article. Review.
Acute hepatic porphyria (AHP) is a group of rare, metabolic diseases where patients can experience acute neurovisceral attacks, chronic symptoms, and long-term complications. Diagnostic biochemical testing is widely available and effective, but a substantial time from symp …
Acute hepatic porphyria (AHP) is a group of rare, metabolic diseases where patients can experience acute neurovisceral attacks, chronic symp …
Pregnancy outcomes and risk of endometrial cancer: A pooled analysis of individual participant data in the Epidemiology of Endometrial Cancer Consortium.
Jordan SJ, Na R, Weiderpass E, Adami HO, Anderson KE, van den Brandt PA, Brinton LA, Chen C, Cook LS, Doherty JA, Du M, Friedenreich CM, Gierach GL, Goodman MT, Krogh V, Levi F, Lu L, Miller AB, McCann SE, Moysich KB, Negri E, Olson SH, Petruzella S, Palmer JR, Parazzini F, Pike MC, Prizment AE, Rebbeck TR, Reynolds P, Ricceri F, Risch HA, Rohan TE, Sacerdote C, Schouten LJ, Serraino D, Setiawan VW, Shu XO, Sponholtz TR, Spurdle AB, Stolzenberg-Solomon RZ, Trabert B, Wentzensen N, Wilkens LR, Wise LA, Yu H, La Vecchia C, De Vivo I, Xu W, Zeleniuch-Jacquotte A, Webb PM. Jordan SJ, et al. Among authors: anderson ke. Int J Cancer. 2021 May 1;148(9):2068-2078. doi: 10.1002/ijc.33360. Epub 2020 Nov 17. Int J Cancer. 2021. PMID: 33105052 Free PMC article.
The risk reduction appeared the greatest for the first full-term pregnancy (OR = 0.78, 95% CI 0.72-0.84), with a further ~15% reduction per pregnancy up to eight pregnancies (OR = 0.20, 95% CI 0.14-0.28) that was independent of age at last full-term pregnancy. ...Ou …
The risk reduction appeared the greatest for the first full-term pregnancy (OR = 0.78, 95% CI 0.72-0.84), with a further ~15% reducti …
Soy isoflavones interact with calcium and contribute to blood pressure homeostasis in women: a randomized, double-blind, placebo controlled trial.
Lu LW, Chen NW, Nayeem F, Nagamani M, Anderson KE. Lu LW, et al. Among authors: anderson ke. Eur J Nutr. 2020 Sep;59(6):2369-2381. doi: 10.1007/s00394-019-02085-3. Epub 2019 Sep 18. Eur J Nutr. 2020. PMID: 31535213 Free PMC article. Clinical Trial.

Isoflavones inversely moderated calcium effects on systolic blood pressure (SBP) (interaction term beta-estimates: - 3.1 for DE, - 12.86 for GE, all P < 0.05), and decreased diastolic blood pressure (DBP) (beta-estimates: - 0.84 for DE, - 2.82 for GE, all P < 0.05) a

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Isoflavones inversely moderated calcium effects on systolic blood pressure (SBP) (interaction term beta-estimates: - 3.1 for DE, - 12 …
47 results