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Improving the biophysical properties of anti-ricin single-domain antibodies.
Turner KB, Liu JL, Zabetakis D, Lee AB, Anderson GP, Goldman ER. Turner KB, et al. Among authors: anderson gp. Biotechnol Rep (Amst). 2015 Jan 15;6:27-35. doi: 10.1016/j.btre.2015.01.001. eCollection 2015 Jun. Biotechnol Rep (Amst). 2015. PMID: 28626694 Free PMC article.
It has been observed that some sdAbs, however, exhibit undesirable properties including reduced solubility when subjected to heating or upon long-term storage at production-relevant concentrations, which can limit their usefulness. ...
It has been observed that some sdAbs, however, exhibit undesirable properties including reduced solubility when subjected to heating or upon …
IL-17A and serum amyloid A are elevated in a cigarette smoke cessation model associated with the persistence of pigmented macrophages, neutrophils and activated NK cells.
Hansen MJ, Chan SP, Langenbach SY, Dousha LF, Jones JE, Yatmaz S, Seow HJ, Vlahos R, Anderson GP, Bozinovski S. Hansen MJ, et al. Among authors: anderson gp. PLoS One. 2014 Nov 18;9(11):e113180. doi: 10.1371/journal.pone.0113180. eCollection 2014. PLoS One. 2014. PMID: 25405776 Free PMC article.
In this study, candidate effector mechanisms were assessed in mice exposed to cigarette smoke (CS) for 4 months following cessation from long term CS exposure. BALF neutrophils, CD4+ and CD8+ T cells and lung innate NK cells remained significantly elevated following smokin …
In this study, candidate effector mechanisms were assessed in mice exposed to cigarette smoke (CS) for 4 months following cessation from lon …
Increased net gelatinase but not serine protease activity in bronchiolitis obliterans syndrome.
Riise GC, Ericson P, Bozinovski S, Yoshihara S, Anderson GP, Lindén A. Riise GC, et al. Among authors: anderson gp. J Heart Lung Transplant. 2010 Jul;29(7):800-7. doi: 10.1016/j.healun.2010.02.010. Epub 2010 Apr 22. J Heart Lung Transplant. 2010. PMID: 20417130
BACKGROUND: Bronchiolitis obliterans syndrome (BOS) is the main long-term complication after lung transplantation. Previous studies indicate that neutrophil mobilization causes high protease concentrations in the lung allograft during BOS. ...
BACKGROUND: Bronchiolitis obliterans syndrome (BOS) is the main long-term complication after lung transplantation. Previous studies i …
Thermostable llama single domain antibodies for detection of botulinum A neurotoxin complex.
Goldman ER, Anderson GP, Conway J, Sherwood LJ, Fech M, Vo B, Liu JL, Hayhurst A. Goldman ER, et al. Among authors: anderson gp. Anal Chem. 2008 Nov 15;80(22):8583-91. doi: 10.1021/ac8014774. Epub 2008 Oct 24. Anal Chem. 2008. PMID: 18947189 Free PMC article.
The unique properties of these sdAb may provide advantages for many diagnostic applications where long-term storage and in-line monitoring require very rugged yet highly specific recognition elements....
The unique properties of these sdAb may provide advantages for many diagnostic applications where long-term storage and in-line monit …
Cigarette smoke worsens lung inflammation and impairs resolution of influenza infection in mice.
Gualano RC, Hansen MJ, Vlahos R, Jones JE, Park-Jones RA, Deliyannis G, Turner SJ, Duca KA, Anderson GP. Gualano RC, et al. Among authors: anderson gp. Respir Res. 2008 Jul 15;9(1):53. doi: 10.1186/1465-9921-9-53. Respir Res. 2008. PMID: 18627612 Free PMC article.
We hypothesized, based on prior gene expression profiling studies, that upregulation of pro-inflammatory mediators by short term smoke exposure would be protective against a subsequent influenza infection. ...
We hypothesized, based on prior gene expression profiling studies, that upregulation of pro-inflammatory mediators by short term smok …
Severe asthma in adults: what are the important questions?
Chanez P, Wenzel SE, Anderson GP, Anto JM, Bel EH, Boulet LP, Brightling CE, Busse WW, Castro M, Dahlen B, Dahlen SE, Fabbri LM, Holgate ST, Humbert M, Gaga M, Joos GF, Levy B, Rabe KF, Sterk PJ, Wilson SJ, Vachier I. Chanez P, et al. Among authors: anderson gp. J Allergy Clin Immunol. 2007 Jun;119(6):1337-48. doi: 10.1016/j.jaci.2006.11.702. Epub 2007 Apr 9. J Allergy Clin Immunol. 2007. PMID: 17416409
The term severe refractory asthma (SRA) in adults applies to patients who remain difficult to control despite extensive re-evaluation of diagnosis and management following an observational period of at least 6 months by a specialist. ...
The term severe refractory asthma (SRA) in adults applies to patients who remain difficult to control despite extensive re-evaluation …
Regulation of hypothalamic NPY by diet and smoking.
Chen H, Hansen MJ, Jones JE, Vlahos R, Bozinovski S, Anderson GP, Morris MJ. Chen H, et al. Among authors: anderson gp. Peptides. 2007 Feb;28(2):384-9. doi: 10.1016/j.peptides.2006.07.034. Epub 2007 Jan 17. Peptides. 2007. PMID: 17207894 Review.
We measured hypothalamic NPY in male Sprague-Dawley rats after short or long term exposure to cafeteria-style high fat diet (32% energy as fat) or laboratory chow (12% fat). ...Hypothalamic NPY concentration was only significantly decreased after long term consumpti …
We measured hypothalamic NPY in male Sprague-Dawley rats after short or long term exposure to cafeteria-style high fat diet (32% ener …
Current issues with beta2-adrenoceptor agonists: pharmacology and molecular and cellular mechanisms.
Anderson GP. Anderson GP. Clin Rev Allergy Immunol. 2006 Oct-Dec;31(2-3):119-30. doi: 10.1385/CRIAI:31:2:119. Clin Rev Allergy Immunol. 2006. PMID: 17085788 Review.
Here, the beta2-adrenoceptor is linked by the G protein, Gs, to adenylyl cyclase, which increases cyclic adenosine monophosphate (cAMP), thus activating protein kinase A, which affects calcium levels and reduces the efficiency of myosin light-chain kinase, causing relaxation. Act …
Here, the beta2-adrenoceptor is linked by the G protein, Gs, to adenylyl cyclase, which increases cyclic adenosine monophosphate (cAMP), thu …
12 results