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Sepsis-associated acute kidney injury.
Alobaidi R, Basu RK, Goldstein SL, Bagshaw SM. Alobaidi R, et al. Semin Nephrol. 2015 Jan;35(1):2-11. doi: 10.1016/j.semnephrol.2015.01.002. Semin Nephrol. 2015. PMID: 25795495 Free PMC article. Review.
Rather, current strategies to alleviate poor outcomes focus on clinical risk identification, early detection of injury, modifying clinician behavior to avoid harm, early appropriate antimicrobial therapy, and surveillance among survivors for the longer-term sequelae of kid …
Rather, current strategies to alleviate poor outcomes focus on clinical risk identification, early detection of injury, modifying clinician …
Consensus-Based Recommendations on Priority Activities to Address Acute Kidney Injury in Children: A Modified Delphi Consensus Statement.
Goldstein SL, Akcan-Arikan A, Alobaidi R, Askenazi DJ, Bagshaw SM, Barhight M, Barreto E, Bayrakci B, Bignall ONR, Bjornstad E, Brophy PD, Chanchlani R, Charlton JR, Conroy AL, Deep A, Devarajan P, Dolan K, Fuhrman DY, Gist KM, Gorga SM, Greenberg JH, Hasson D, Ulrich EH, Iyengar A, Jetton JG, Krawczeski C, Meigs L, Menon S, Morgan J, Morgan CJ, Mottes T, Neumayr TM, Ricci Z, Selewski D, Soranno DE, Starr M, Stanski NL, Sutherland SM, Symons J, Tavares MS, Vega MW, Zappitelli M, Ronco C, Mehta RL, Kellum J, Ostermann M, Basu RK; Pediatric ADQI Collaborative. Goldstein SL, et al. Among authors: alobaidi r. JAMA Netw Open. 2022 Sep 1;5(9):e2229442. doi: 10.1001/jamanetworkopen.2022.29442. JAMA Netw Open. 2022. PMID: 36178697 Free PMC article.
IMPORTANCE: Increasing evidence indicates that acute kidney injury (AKI) occurs frequently in children and young adults and is associated with poor short-term and long-term outcomes. Guidance is required to focus efforts related to expansion of pediatric AKI knowled …
IMPORTANCE: Increasing evidence indicates that acute kidney injury (AKI) occurs frequently in children and young adults and is associated wi …
Acute Kidney Injury in Critically Ill Children Is Not all Acute: Lessons Over the Last 5 Years.
Hessey E, Melhem N, Alobaidi R, Ulrich E, Morgan C, Bagshaw SM, Sinha MD. Hessey E, et al. Among authors: alobaidi r. Front Pediatr. 2021 Mar 15;9:648587. doi: 10.3389/fped.2021.648587. eCollection 2021. Front Pediatr. 2021. PMID: 33791260 Free PMC article. Review.
To date, there are no guidelines for follow-up of surviving children that may be at risk of long-term sequelae following AKI in the PICU. This narrative review aims to describe literature from the last 5 years on the risk of medium and long-term kidney and non-kidne …
To date, there are no guidelines for follow-up of surviving children that may be at risk of long-term sequelae following AKI in the P …
Major Adverse Kidney Events in Pediatric Continuous Kidney Replacement Therapy.
Fuhrman DY, Stenson EK, Alhamoud I, Alobaidi R, Bottari G, Fernandez S, Guzzi F, Haga T, Kaddourah A, Marinari E, Mohamed TH, Morgan CJ, Mottes T, Neumayr TM, Ollberding NJ, Raggi V, Ricci Z, See E, Stanski NL, Zang H, Zangla E, Gist KM; WE-ROCK Investigators. Fuhrman DY, et al. Among authors: alobaidi r. JAMA Netw Open. 2024 Feb 5;7(2):e240243. doi: 10.1001/jamanetworkopen.2024.0243. JAMA Netw Open. 2024. PMID: 38393726 Free PMC article.
IMPORTANCE: Continuous kidney replacement therapy (CKRT) is increasingly used in youths with critical illness, but little is known about longer-term outcomes, such as persistent kidney dysfunction, continued need for dialysis, or death. ...
IMPORTANCE: Continuous kidney replacement therapy (CKRT) is increasingly used in youths with critical illness, but little is known about lon …
Worldwide Exploration of Renal Replacement Outcomes Collaborative in Kidney Disease (WE-ROCK).
Menon S, Krallman KA, Arikan AA, Fuhrman DY, Gorga SM, Mottes T, Ollberding N, Ricci Z, Stanski NL, Selewski DT, Soranno DE, Zappitelli M, Zang H, Gist KM; WE-ROCK Investigators. Menon S, et al. Kidney Int Rep. 2023 Jun 5;8(8):1542-1552. doi: 10.1016/j.ekir.2023.05.026. eCollection 2023 Aug. Kidney Int Rep. 2023. PMID: 37547524 Free PMC article.
METHODS: The Worldwide Exploration of Renal Replacement Outcomes Collaborative in Kidney Disease (WE-ROCK) is an international collaborative of pediatric specialists whose mission is to improve short- and long-term outcomes of children treated with CRRT. The aims of this m …
METHODS: The Worldwide Exploration of Renal Replacement Outcomes Collaborative in Kidney Disease (WE-ROCK) is an international collaborative …
Epidemiology of acute kidney injury in children: a report from the 26th Acute Disease Quality Initiative (ADQI) consensus conference.
Sutherland SM, Alobaidi R, Gorga SM, Iyengar A, Morgan C, Heydari E, Arikan AAA, Basu RK, Goldstein SL, Zappitelli M; ADQI 26 Workgroup. Sutherland SM, et al. Among authors: alobaidi r. Pediatr Nephrol. 2024 Mar;39(3):919-928. doi: 10.1007/s00467-023-06164-w. Epub 2023 Oct 24. Pediatr Nephrol. 2024. PMID: 37874357 Free PMC article.
In particular, the areas of community acquired AKI, AKI in non-critically ill children, and cohorts from low-middle income countries have not been well studied. Longer-term functional outcomes and patient-centric metrics including social determinants of health, quality of …
In particular, the areas of community acquired AKI, AKI in non-critically ill children, and cohorts from low-middle income countries have no …
Fluid assessment, fluid balance, and fluid overload in sick children: a report from the Pediatric Acute Disease Quality Initiative (ADQI) conference.
Selewski DT, Barhight MF, Bjornstad EC, Ricci Z, de Sousa Tavares M, Akcan-Arikan A, Goldstein SL, Basu R, Bagshaw SM; Pediatric the Acute Disease Quality Initiative (ADQI) Consensus Committee Members. Selewski DT, et al. Pediatr Nephrol. 2024 Mar;39(3):955-979. doi: 10.1007/s00467-023-06156-w. Epub 2023 Nov 7. Pediatr Nephrol. 2024. PMID: 37934274 Free PMC article.
Recommendations include that the terms daily fluid balance, cumulative fluid balance, and percent cumulative fluid balance be utilized to describe the fluid status of sick children. The term fluid overload is to be preserved for describing a pathologic state of positive fl …
Recommendations include that the terms daily fluid balance, cumulative fluid balance, and percent cumulative fluid balance be utilized to de …
Weight as a Risk Factor for Mortality in Critically Ill Patients.
Ayalon I, Woo JG, Basu RK, Kaddourah A, Goldstein SL, Kaplan JM; AWARE Investigators. Ayalon I, et al. Pediatrics. 2020 Aug;146(2):e20192829. doi: 10.1542/peds.2019-2829. Epub 2020 Jul 3. Pediatrics. 2020. PMID: 32620676 Free PMC article.
CONCLUSIONS: Patients who are underweight make up a significant proportion of all patients in the PICU, have a higher short-term mortality rate, and have a more complicated ICU course....
CONCLUSIONS: Patients who are underweight make up a significant proportion of all patients in the PICU, have a higher short-term mort …
Outcomes of Prophylactic Peritoneal Dialysis Catheter Insertion in Children Undergoing Cardiac Surgery: A Systematic Review and Meta-Analysis.
Ulrich EH, Bedi PK, Alobaidi R, Morgan CJ, Paulden M, Zappitelli M, Bagshaw SM. Ulrich EH, et al. Among authors: alobaidi r. Pediatr Crit Care Med. 2024 Feb 9. doi: 10.1097/PCC.0000000000003465. Online ahead of print. Pediatr Crit Care Med. 2024. PMID: 38334438
DATA EXTRACTION: The primary outcome was in-hospital mortality, as well as secondary short-term outcomes. Pooled random-effect meta-analysis odds ratio with 95% CI are reported. ...CONCLUSIONS: In this meta-analysis, we have failed to demonstrate an association between pro …
DATA EXTRACTION: The primary outcome was in-hospital mortality, as well as secondary short-term outcomes. Pooled random-effect meta-a …
Programs and processes for advancing pediatric acute kidney support therapy in hospitalized and critically ill children: a report from the 26th Acute Disease Quality Initiative (ADQI) consensus conference.
Neumayr TM, Bayrakci B, Chanchlani R, Deep A, Morgan J, Arikan AA, Basu RK, Goldstein SL, Askenazi DJ; ADQI 26 workgroup. Neumayr TM, et al. Pediatr Nephrol. 2024 Mar;39(3):993-1004. doi: 10.1007/s00467-023-06186-4. Epub 2023 Nov 6. Pediatr Nephrol. 2024. PMID: 37930418 Free PMC article.
Little is known about optimal ways to configure paKST teams and programs, pediatric-specific aspects of delivering high-quality paKST, strategies for transitioning from acute continuous modes of paKST to facilitate rehabilitation, or providing effective short- and long-term …
Little is known about optimal ways to configure paKST teams and programs, pediatric-specific aspects of delivering high-quality paKST, strat …