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Short-term toxicity studies of thallium (I) sulfate administered in drinking water to Sprague Dawley rats and B6C3F1/N mice.
Shipkowski KA, Hubbard TD, Ryan K, Waidyanatha S, Cunny H, Shockley KR, Allen JL, Toy H, Levine K, Harrington J, Betz L, Sparrow B, Roberts GK. Shipkowski KA, et al. Among authors: allen jl. Toxicol Rep. 2023 May 11;10:621-632. doi: 10.1016/j.toxrep.2023.05.003. eCollection 2023. Toxicol Rep. 2023. PMID: 37250531 Free PMC article.
To address this data gap, the Division of Translational Toxicology conducted short-term toxicity studies of a monovalent thallium salt, thallium (I) sulfate. ...
To address this data gap, the Division of Translational Toxicology conducted short-term toxicity studies of a monovalent thallium sal …
Computational Design of FastFES Treatment to Improve Propulsive Force Symmetry During Post-stroke Gait: A Feasibility Study.
Sauder NR, Meyer AJ, Allen JL, Ting LH, Kesar TM, Fregly BJ. Sauder NR, et al. Among authors: allen jl. Front Neurorobot. 2019 Oct 1;13:80. doi: 10.3389/fnbot.2019.00080. eCollection 2019. Front Neurorobot. 2019. PMID: 31632261 Free PMC article.
Stroke is a leading cause of long-term disability worldwide and often impairs walking ability. To improve recovery of walking function post-stroke, researchers have investigated the use of treatments such as fast functional electrical stimulation (FastFES). ...
Stroke is a leading cause of long-term disability worldwide and often impairs walking ability. To improve recovery of walking functio …
Somatic evolution and global expansion of an ancient transmissible cancer lineage.
Baez-Ortega A, Gori K, Strakova A, Allen JL, Allum KM, Bansse-Issa L, Bhutia TN, Bisson JL, Briceño C, Castillo Domracheva A, Corrigan AM, Cran HR, Crawford JT, Davis E, de Castro KF, B de Nardi A, de Vos AP, Delgadillo Keenan L, Donelan EM, Espinoza Huerta AR, Faramade IA, Fazil M, Fotopoulou E, Fruean SN, Gallardo-Arrieta F, Glebova O, Gouletsou PG, Häfelin Manrique RF, Henriques JJGP, Horta RS, Ignatenko N, Kane Y, King C, Koenig D, Krupa A, Kruzeniski SJ, Kwon YM, Lanza-Perea M, Lazyan M, Lopez Quintana AM, Losfelt T, Marino G, Martínez Castañeda S, Martínez-López MF, Meyer M, Migneco EJ, Nakanwagi B, Neal KB, Neunzig W, Ní Leathlobhair M, Nixon SJ, Ortega-Pacheco A, Pedraza-Ordoñez F, Peleteiro MC, Polak K, Pye RJ, Reece JF, Rojas Gutierrez J, Sadia H, Schmeling SK, Shamanova O, Sherlock AG, Stammnitz M, Steenland-Smit AE, Svitich A, Tapia Martínez LJ, Thoya Ngoka I, Torres CG, Tudor EM, van der Wel MG, Viţălaru BA, Vural SA, Walkinton O, Wang J, Wehrle-Martinez AS, Widdowson SAE, Stratton MR, Alexandrov LB, Martincorena I, Murchison EP. Baez-Ortega A, et al. Among authors: allen jl. Science. 2019 Aug 2;365(6452):eaau9923. doi: 10.1126/science.aau9923. Science. 2019. PMID: 31371581 Free PMC article.
We illustrate how long-lived clonal organisms capture changing mutagenic environments, and reveal that neutral genetic drift is the dominant feature of long-term cancer evolution....
We illustrate how long-lived clonal organisms capture changing mutagenic environments, and reveal that neutral genetic drift is the dominant …
Machine-learning to stratify diabetic patients using novel cardiac biomarkers and integrative genomics.
Hathaway QA, Roth SM, Pinti MV, Sprando DC, Kunovac A, Durr AJ, Cook CC, Fink GK, Cheuvront TB, Grossman JH, Aljahli GA, Taylor AD, Giromini AP, Allen JL, Hollander JM. Hathaway QA, et al. Among authors: allen jl. Cardiovasc Diabetol. 2019 Jun 11;18(1):78. doi: 10.1186/s12933-019-0879-0. Cardiovasc Diabetol. 2019. PMID: 31185988 Free PMC article.
While HbA1c remains the primary diagnostic for diabetics, its ability to predict long-term, health outcomes across diverse demographics, ethnic groups, and at a personalized level are limited. ...
While HbA1c remains the primary diagnostic for diabetics, its ability to predict long-term, health outcomes across diverse demographi …
Lung-Specific Extracellular Superoxide Dismutase Improves Cognition of Adult Mice Exposed to Neonatal Hyperoxia.
Buczynski BW, Mai N, Yee M, Allen JL, Prifti L, Cory-Slechta DA, Halterman MW, O'Reilly MA. Buczynski BW, et al. Among authors: allen jl. Front Med (Lausanne). 2018 Dec 10;5:334. doi: 10.3389/fmed.2018.00334. eCollection 2018. Front Med (Lausanne). 2018. PMID: 30619855 Free PMC article.
These findings demonstrate pulmonary expression of EC-SOD preserves short-term memory in adult female mice exposed to neonatal hyperoxia, thus suggesting anti-oxidants designed to alleviate oxygen-induced lung disease such as in preterm infants may also be neuroprotective. …
These findings demonstrate pulmonary expression of EC-SOD preserves short-term memory in adult female mice exposed to neonatal hypero …
PRE-surgical Metformin In Uterine Malignancy (PREMIUM): a Multi-Center, Randomized Double-Blind, Placebo-Controlled Phase III Trial.
Kitson SJ, Maskell Z, Sivalingam VN, Allen JL, Ali S, Burns S, Gilmour K, Latheef R, Slade RJ, Pemberton PW, Shaw J, Ryder WD, Kitchener HC, Crosbie EJ. Kitson SJ, et al. Among authors: allen jl. Clin Cancer Res. 2019 Apr 15;25(8):2424-2432. doi: 10.1158/1078-0432.CCR-18-3339. Epub 2018 Dec 18. Clin Cancer Res. 2019. PMID: 30563932 Free PMC article. Clinical Trial.
Metformin did not affect expression of markers of the PI3K-Akt-mTOR or insulin signaling pathways, and did not result in weight loss. CONCLUSIONS: Short-term treatment with standard diabetic doses of metformin does not reduce tumor proliferation in women with endometrioid …
Metformin did not affect expression of markers of the PI3K-Akt-mTOR or insulin signaling pathways, and did not result in weight loss. CONCLU …
Nanoporous Immunoprotective Device for Stem-Cell-Derived β-Cell Replacement Therapy.
Chang R, Faleo G, Russ HA, Parent AV, Elledge SK, Bernards DA, Allen JL, Villanueva K, Hebrok M, Tang Q, Desai TA. Chang R, et al. Among authors: allen jl. ACS Nano. 2017 Aug 22;11(8):7747-7757. doi: 10.1021/acsnano.7b01239. Epub 2017 Aug 7. ACS Nano. 2017. PMID: 28763191 Free PMC article.
The device also successfully prevented teratoma escape into the peritoneal cavity of mice. Long-term animal studies demonstrate evidence of engraftment, viability, and function of cells encapsulated in the device after 6 months. ...
The device also successfully prevented teratoma escape into the peritoneal cavity of mice. Long-term animal studies demonstrate evide …
Cognitive Effects of Air Pollution Exposures and Potential Mechanistic Underpinnings.
Allen JL, Klocke C, Morris-Schaffer K, Conrad K, Sobolewski M, Cory-Slechta DA. Allen JL, et al. Curr Environ Health Rep. 2017 Jun;4(2):180-191. doi: 10.1007/s40572-017-0134-3. Curr Environ Health Rep. 2017. PMID: 28435996 Free PMC article. Review.
Studies in animal models are significantly more limited in number, with somewhat inconsistent findings to date for measures of learning, but show more consistent impairments for short-term memory. Potential contributory mechanisms include oxidative stress/inflammation, alt …
Studies in animal models are significantly more limited in number, with somewhat inconsistent findings to date for measures of learning, but …
Increased neuromuscular consistency in gait and balance after partnered, dance-based rehabilitation in Parkinson's disease.
Allen JL, McKay JL, Sawers A, Hackney ME, Ting LH. Allen JL, et al. J Neurophysiol. 2017 Jul 1;118(1):363-373. doi: 10.1152/jn.00813.2016. Epub 2017 Apr 5. J Neurophysiol. 2017. PMID: 28381488 Free PMC article.
Our work is the first to show that motor module distinctness, consistency, and generalizability are more sensitive to improvements in gait and balance function after short-term rehabilitation than motor module number. Moreover, as similar differences in motor module distin …
Our work is the first to show that motor module distinctness, consistency, and generalizability are more sensitive to improvements in gait a …
Long-term training modifies the modular structure and organization of walking balance control.
Sawers A, Allen JL, Ting LH. Sawers A, et al. Among authors: allen jl. J Neurophysiol. 2015 Dec;114(6):3359-73. doi: 10.1152/jn.00758.2015. Epub 2015 Oct 14. J Neurophysiol. 2015. PMID: 26467521 Free PMC article.
How does long-term training affect the neural control of movements? Here we tested the hypothesis that long-term training leading to skilled motor performance alters muscle coordination during challenging, as well as nominal everyday motor behaviors. ...
How does long-term training affect the neural control of movements? Here we tested the hypothesis that long-term training lead …
18 results