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Activity of xenobiotic-metabolizing enzymes in the liver of rats with multi-vitamin deficiency.
Tutelyan VA, Kravchenko LV, Aksenov IV, Trusov NV, Guseva GV, Kodentsova VM, Vrzhesinskaya OA, Beketova NA. Tutelyan VA, et al. Among authors: aksenov iv. Int J Vitam Nutr Res. 2013;83(1):5-13. doi: 10.1024/0300-9831/a000140. Int J Vitam Nutr Res. 2013. PMID: 24220160
The study has demonstrated that profound multi-vitamin deficiency is associated with a decrease in the expression of CYP1A2 and CYP3A1 mRNAs to 62 % and 79 %, respectively. These data indicated that a short-term but profound multi-vitamin deficiency in rats leads to a decr …
The study has demonstrated that profound multi-vitamin deficiency is associated with a decrease in the expression of CYP1A2 and CYP3A1 mRNAs …