A phage nucleus-associated RNA-binding protein is required for jumbo phage infection.
Enustun E, Armbruster EG, Lee J, Zhang S, Yee BA, Malukhina K, Gu Y, Deep A, Naritomi JT, Liang Q, Aigner S, Adler BA, Cress BF, Doudna JA, Chaikeeratisak V, Cleveland DW, Ghassemian M, Bintu B, Yeo GW, Pogliano J, Corbett KD.
Enustun E, et al. Among authors: adler ba.
Nucleic Acids Res. 2024 Mar 30:gkae216. doi: 10.1093/nar/gkae216. Online ahead of print.
Nucleic Acids Res. 2024.
PMID: 38554115
Here, we identify a conserved phage nuclear shell-associated protein that we term Chimallin C (ChmC), which adopts a nucleic acid-binding fold, binds RNA with high affinity in vitro, and binds phage mRNAs in infected cells. ...
Here, we identify a conserved phage nuclear shell-associated protein that we term Chimallin C (ChmC), which adopts a nucleic acid-bin …